Research ArticleSpecial Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine
A Mathematical Model to Investigate the Effects of Ceralasertib and Olaparib in Targeting the Cellular DNA Damage Response Pathway
Kira Pugh, Michael Davies and Gibin Powathil
Journal of Pharmacology and Experimental Therapeutics October 2023, 387 (1) 55-65; DOI: https://doi.org/10.1124/jpet.122.001558
Kira Pugh
Department of Mathematics, Faculty of Science and Engineering, Swansea University, Swansea, United Kingdom (K.P., G.P.) and Oncology R&D, AstraZeneca, Cambridge, United Kingdom (M.D.)
Michael Davies
Department of Mathematics, Faculty of Science and Engineering, Swansea University, Swansea, United Kingdom (K.P., G.P.) and Oncology R&D, AstraZeneca, Cambridge, United Kingdom (M.D.)
Gibin Powathil
Department of Mathematics, Faculty of Science and Engineering, Swansea University, Swansea, United Kingdom (K.P., G.P.) and Oncology R&D, AstraZeneca, Cambridge, United Kingdom (M.D.)

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Research ArticleSpecial Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine
Modelling the Effects of DNA Damage Response Inhibitor Drugs
Kira Pugh, Michael Davies and Gibin Powathil
Journal of Pharmacology and Experimental Therapeutics October 1, 2023, 387 (1) 55-65; DOI: https://doi.org/10.1124/jpet.122.001558
Research ArticleSpecial Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine
Modelling the Effects of DNA Damage Response Inhibitor Drugs
Kira Pugh, Michael Davies and Gibin Powathil
Journal of Pharmacology and Experimental Therapeutics October 1, 2023, 387 (1) 55-65; DOI: https://doi.org/10.1124/jpet.122.001558
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