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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

June 01, 2023; Volume 385,Issue 3

Viewpoint

  • You have access
    Bath Salts to Therapies: Can Separation of Adverse and Therapeutic Effects of Substituted Cathinones Lead to a Medication for Psychostimulant Use Disorder?
    Ellen M. Unterwald and Scott M. Rawls
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 159-161; DOI: https://doi.org/10.1124/jpet.123.001650
  • You have access
    Neurochemical and Cardiovascular Effects of 4-Chloro Ring-Substituted Synthetic Cathinones in Rats
    Michael R. Chojnacki, Eric B. Thorndike, John S. Partilla, Kenner C. Rice, Charles W. Schindler and Michael H. Baumann
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 162-170; DOI: https://doi.org/10.1124/jpet.122.001478

Behavioral Pharmacology

  • You have access
    Assessment of Abuse-Related Discriminative Stimulus Effects of Nicotine Aerosol in Rodents
    Yasmin Alkhlaif and Keith L. Shelton
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 171-179; DOI: https://doi.org/10.1124/jpet.122.001520
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    Pharmacokinetic and Pharmacodynamic Consequences of Cytochrome P450 3A Inhibition on Mitragynine Metabolism in Rats
    Shyam H. Kamble, Samuel Obeng, Francisco León, Luis F. Restrepo, Tamara I. King, Erin C. Berthold, Siva Rama Raju Kanumuri, Lea R. Gamez-Jimenez, Victoria L.C. Pallares, Avi Patel, Nicholas P. Ho, Aidan Hampson, Christopher R. McCurdy, Lance R. McMahon, Jenny L. Wilkerson, Abhisheak Sharma and Takato Hiranita
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 180-192; DOI: https://doi.org/10.1124/jpet.122.001525

Drug Discovery and Translational Medicine

  • Open Access
    TAK-994, a Novel Orally Available Brain-Penetrant Orexin 2 Receptor-Selective Agonist, Suppresses Fragmentation of Wakefulness and Cataplexy-Like Episodes in Mouse Models of Narcolepsy
    Takashi Ishikawa, Hiroe Hara, Ayumi Kawano, Kimio Tohyama, Yuichi Kajita, Yuhei Miyanohana, Tatsuki Koike and Haruhide Kimura
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 193-204; DOI: https://doi.org/10.1124/jpet.122.001449
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    In Vivo Pharmacokinetic and Pharmacodynamic Properties of the Antiarrhythmic Molecule ent-Verticilide
    Daniel J. Blackwell, Abigail N. Smith, Tri Do, Aaron Gochman, Jeffrey Schmeckpeper, Corey R. Hopkins, Wendell S. Akers, Jeffrey N. Johnston and Bjorn C. Knollmann
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 205-213; DOI: https://doi.org/10.1124/jpet.122.001455

Endocrine and Diabetes

  • BI-Y, an Neuropilin-1 Antagonist, Enhances Revascularization and Prevents Vascular Endothelial Growth Factor-A Induced Retinal Hyperpermeability in Rodent Models of Retinopathies
    Open Access
    BI-Y, an Neuropilin-1 Antagonist, Enhances Revascularization and Prevents Vascular Endothelial Growth Factor-A Induced Retinal Hyperpermeability in Rodent Models of Retinopathies
    Leo Thomas, Sarah Low, Gale Hansen, Remko A. Bakker and Nina Zippel
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 214-221; DOI: https://doi.org/10.1124/jpet.122.001473

Erratum

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    Correction to “Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice”
    Journal of Pharmacology and Experimental Therapeutics June 2023, 385 (3) 222; DOI: https://doi.org/10.1124/jpet.122.001367err
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Journal of Pharmacology and Experimental Therapeutics: 385 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 385, Issue 3
1 Jun 2023
  • Table of Contents
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  • Behavioral Pharmacology
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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