Journal of Pharmacology and Experimental Therapeutics: 385 (2)

May 01, 2023; Volume 385,Issue 2

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Alterations in Brain Neural Network and Stress System in Atopic Dermatitis: Novel Therapeutic Interventions
Yutaka Nakagawa and Shizuo Yamada

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 78-87; DOI: https://doi.org/10.1124/jpet.122.001482

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The Anti-Inflammatory Effects and Clinical Potential of Dexmedetomidine in Pulmonary Arterial Hypertension
Yohei Yamaguchi, Susumu Hosokawa, Go Haraguchi, Yusuke Kajikawa, Makito Sakurai, Taku Ishii, Noboru Ando, Tomohiro Morio, Shozaburo Doi and Tetsushi Furukawa

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 88-94; DOI: https://doi.org/10.1124/jpet.122.001399

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Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer
Clara Wong, Maria Carmen Mulero, Erika I. Barth, Katherine Wang, Xiying Shang, Sanika Tikle, Catherine Rice, Dennis Gately and Stephen B. Howell

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 95-105; DOI: https://doi.org/10.1124/jpet.122.001495

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Combining SOS1 and MEK Inhibitors in a Murine Model of Plexiform Neurofibroma Results in Tumor Shrinkage
Mark Jackson, Niousha Ahmari, Jianqiang Wu, Tilat A. Rizvi, Elizabeth Fugate, Mi-OK Kim, Eva Dombi, Heribert Arnhof, Guido Boehmelt, Matthias J. Düchs, Clive J. Long, Udo Maier, Francesca Trapani, Marco H. Hofmann and Nancy Ratner

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 106-116; DOI: https://doi.org/10.1124/jpet.122.001431
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Heroin- and Fentanyl-Induced Respiratory Depression in a Rat Plethysmography Model: Potency, Tolerance, and Sex Differences
Renata C.N. Marchette, Erika R. Carlson, Emma V. Frye, Lyndsay E. Hastings, Janaina C.M. Vendruscolo, Gustavo Mejias-Torres, Stephen J. Lewis, Aidan Hampson, Nora D. Volkow, Leandro F. Vendruscolo and George F. Koob

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 117-134; DOI: https://doi.org/10.1124/jpet.122.001476

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Effects of Volatile Anesthetics versus Ketamine on Blood-Brain Barrier Permeability via Lipid-Mediated Alterations of Endothelial Cell Membranes
Behnam Noorani, Ekram Ahmed Chowdhury, Faleh Alqahtani, Yeseul Ahn, Ehsan Nozohouri, Sumaih Zoubi, Dhavalkumar Patel, Laurence Wood, Juyang Huang, Muhammad Bilal Siddique, Abraham Al-Ahmad, Reza Mehvar and Ulrich Bickel

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 135-145; DOI: https://doi.org/10.1124/jpet.122.001281

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Ventral Tegmental Area M5 Muscarinic Receptors Mediate Effort-Choice Responding and Nucleus Accumbens Dopamine in a Sex-Specific Manner
Eric J. Nunes, Nardos Kebede, Joshua L. Haight, Daniel J. Foster, Craig W. Lindsley, P. Jeffrey Conn and Nii A. Addy

Journal of Pharmacology and Experimental Therapeutics May 2023, 385 (2) 146-156; DOI: https://doi.org/10.1124/jpet.122.001438