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Research ArticleBehavioral Pharmacology

Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice

Mary K. Piscura, Diana E. Sepulveda, Malabika Maulik, Josée Guindon, Angela N. Henderson-Redmond and Daniel J. Morgan
Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 17-34; DOI: https://doi.org/10.1124/jpet.122.001367
Mary K. Piscura
Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
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Diana E. Sepulveda
Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
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Malabika Maulik
Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
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Josée Guindon
Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
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Angela N. Henderson-Redmond
Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
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Daniel J. Morgan
Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
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Article Information

vol. 385 no. 1 17-34
DOI 
https://doi.org/10.1124/jpet.122.001367
PubMed 
36669876

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received June 29, 2022
  • Accepted January 10, 2023
  • Published online March 16, 2023.

Article Versions

  • Earlier version (January 20, 2023 - 12:08).
  • Earlier version (February 22, 2023 - 11:36).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2023 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mary K. Piscura,
  2. Diana E. Sepulveda,
  3. Malabika Maulik,
  4. Josée Guindon,
  5. Angela N. Henderson-Redmond, and
  6. Daniel J. Morgan
  1. Department of Biomedical Sciences, Marshall University, Huntington, West Virginia (M.K.P., M.M., A.N.H.-R., D.J.M.); Department of Pharmacology (D.E.S.) and Graduate Program in Anatomy (M.K.P.), Penn State University College of Medicine, Hershey, Pennsylvania; and Department of Pharmacology and Neuroscience (J.G.) and Center of Excellence for Translational Neuroscience and Therapeutics (J.G.), Texas Tech University Health Sciences Center, Lubbock, Texas
  1. Address correspondence to:
    Daniel Morgan, Department of Biomedical Sciences, Marshall University, 1700 3rd Ave, Huntington, WV 25703. E-mail: morganda{at}marshall.edu; or Angela N. Henderson-Redmond, Department of Biomedical Sciences, Marshall University, 1700 3rd Ave, Huntington, WV 25703. E-mail: redmonda{at}marshall.edu
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Feb 2023228089
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Apr 20232151731
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Journal of Pharmacology and Experimental Therapeutics: 385 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 385, Issue 1
1 Apr 2023
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Research ArticleBehavioral Pharmacology

Role of Residues S426 and S430 in Cannabinoid Tolerance

Mary K. Piscura, Diana E. Sepulveda, Malabika Maulik, Josée Guindon, Angela N. Henderson-Redmond and Daniel J. Morgan
Journal of Pharmacology and Experimental Therapeutics April 1, 2023, 385 (1) 17-34; DOI: https://doi.org/10.1124/jpet.122.001367

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Research ArticleBehavioral Pharmacology

Role of Residues S426 and S430 in Cannabinoid Tolerance

Mary K. Piscura, Diana E. Sepulveda, Malabika Maulik, Josée Guindon, Angela N. Henderson-Redmond and Daniel J. Morgan
Journal of Pharmacology and Experimental Therapeutics April 1, 2023, 385 (1) 17-34; DOI: https://doi.org/10.1124/jpet.122.001367
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