Journal of Pharmacology and Experimental Therapeutics: 385 (1)

April 01, 2023; Volume 385,Issue 1

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Complexity in Hepatic Insulin Resistance – Unraveling the Role of Ubiquitin-Specific Protease 14 in Protein Homeostasis of Metabolic Transcription Factors
Nadya M. Morrow and Erin E. Mulvihill

Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 1-4; DOI: https://doi.org/10.1124/jpet.122.001517
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Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes
Kyoko Kamoshita, Kiyo-aki Ishii, Yumiko Tahira, Akihiro Kikuchi, Halimulati Abuduwaili, Natsumi Tajima-Shirasaki, Qifang Li, Hiroaki Takayama, Kunio Matsumoto and Toshinari Takamura

Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 5-16; DOI: https://doi.org/10.1124/jpet.122.001088

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Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice
Mary K. Piscura, Diana E. Sepulveda, Malabika Maulik, Josée Guindon, Angela N. Henderson-Redmond and Daniel J. Morgan

Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 17-34; DOI: https://doi.org/10.1124/jpet.122.001367

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Endothelial-Specific Targeting of RhoA Signaling via CD31 Antibody-Conjugated Nanoparticles
Behnaz Lahooti, Racheal G. Akwii, Dhavalkumar Patel, Siavash ShahbaziNia, Margarita Lamprou, Mahboubeh Madadi, Thomas J. Abbruscato, Aristotelis Astrinidis, Ulrich Bickel, Abraham Al-Ahmad, Nadezhda A. German, George Mattheolabakis and Constantinos M. Mikelis

Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 35-49; DOI: https://doi.org/10.1124/jpet.122.001384

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Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation
Kamal P. Pandey, Branka Divović, Farjana Rashid, Lalit K. Golani, Rok Cerne, Nicolas M. Zahn, Michelle Jean Meyer, Leggy A. Arnold, Dishary Sharmin, Md Yeunus Mian, Jodi L. Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, V.V.N. Phani Babu Tiruveedhula, James M. Cook, Miroslav M. Savić and Jeffrey M. Witkin

Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 50-61; DOI: https://doi.org/10.1124/jpet.122.001362
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Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)_2A Receptor (5-HT_2AR), 5-HT_2CR, 5-HT_1AR, and Serotonin Transporter
Laura B. Kozell, Amy J. Eshleman, Tracy L. Swanson, Shelley H. Bloom, Katherine M. Wolfrum, Jennifer L. Schmachtenberg, Randall J. Olson, Aaron Janowsky and Atheir I. Abbas

Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 62-75; DOI: https://doi.org/10.1124/jpet.122.001454

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Correction to “Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice”
Journal of Pharmacology and Experimental Therapeutics April 2023, 385 (1) 76-77; DOI: https://doi.org/10.1124/jpet.115.231100err