| Mean Arterial Blood Pressure (mm Hg) |
Vehicle (n = 6) | 112 ± 4 | 108 ± 3 | 107 ± 3 | NS |
8-Aminoguanine (n = 5) | 102 ± 5 | 103 ± 4 | 103 ± 4 | NS |
8-Aminoinosine (n = 9) | 108 ± 3 | 114 ± 4 | 109 ± 2 | NS |
8-Aminohypoxanthine (n = 6) | 110 ± 3 | 120 ± 8 | 117 ± 6 | NS |
| Heart Rate (beats/min) |
Vehicle (n = 6) | 404 ± 12 | 390 ± 16 | 384 ± 20 | NS |
8-Aminoguanine (n = 5) | 377 ± 13 | 372 ± 14 | 372 ± 13 | NS |
8-Aminoinosine (n = 9) | 398 ± 16 | 395 ± 14 | 389 ± 14 | NS |
8-Aminohypoxanthine (n = 6) | 393 ± 7 | 380a ± 4 | 372a ± 6 | 0.0005 |
| Renal Blood Flow (ml/min) |
Vehicle (n = 6) | 7.8 ± 1.2 | 7.8 ± 1.1 | 8.2 ± 1.0 | NS |
8-Aminoguanine (n = 5) | 5.9 ± 0.7 | 5.2 ± 0.6 | 5.5 ± 0.8 | NS |
8-Aminoinosine (n = 9) | 7.4 ± 0.5 | 6.6 ± 0.5 | 6.8 ± 0.4 | NS |
8-Aminohypoxanthine (n = 6) | 8.2 ± 0.9 | 6.7a ± 0.5 | 6.8a ± 0.6 | 0.0244 |
| Mesenteric Blood Flow (ml/min) |
Vehicle (n = 6) | 13.3 ± 2.4 | 13.0 ± 2.0 | 12.7 ± 1.8 | NS |
8-Aminoguanine (n = 5) | 9.8 ± 2.2 | 10.8 ± 2.4 | 13.1 ± 2.6 | NS |
8-Aminoinosine (n = 9) | 11.8 ± 1.0 | 11.9 ± 1.1 | 11.3 ± 1.1 | NS |
8-Aminohypoxanthine (n = 6) | 14.5 ± 3.1 | 16.1b ± 3.6 | 12.8 ± 2.3 | 0.0400 |