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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

February 01, 2022; Volume 380,Issue 2

Gastrointestinal, Hepatic, Pulmonary, and Renal

  • You have access
    Evidence for Alpha7 Nicotinic Receptor Activation During the Cough Suppressing Effects Induced by Nicotine and Identification of ATA-101 as a Potential Novel Therapy for the Treatment of Chronic Cough
    Brendan J. Canning, Qi Liu, Mayuko Tao, Robert DeVita, Michael Perelman, Douglas W. Hay, Peter V. Dicpinigaitis and Jing Liang
    Journal of Pharmacology and Experimental Therapeutics February 2022, 380 (2) 94-103; DOI: https://doi.org/10.1124/jpet.121.000641

Metabolism, Transport, and Pharmacogenetics

  • Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors
    You have access
    Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors
    Chitra Saran, Louise Sundqvist, Henry Ho, Jonna Niskanen, Paavo Honkakoski and Kim L. R. Brouwer
    Journal of Pharmacology and Experimental Therapeutics February 2022, 380 (2) 114-125; DOI: https://doi.org/10.1124/jpet.121.000828

Neuropharmacology

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    Intravenous and Intramuscular Allopregnanolone for Early Treatment of Status Epilepticus: Pharmacokinetics, Pharmacodynamics, and Safety in Dogs
    Irene Vuu, Edward E. Patterson, Chun-Yi Wu, Dorota Zolkowska, Ilo E. Leppik, Michael A. Rogawski, Gregory A. Worrell, Vaclav Kremen, James C. Cloyd and Lisa D. Coles
    Journal of Pharmacology and Experimental Therapeutics February 2022, 380 (2) 104-113; DOI: https://doi.org/10.1124/jpet.121.000736
  • Open Access
    Post-Stroke Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Attenuates Chronic Changes in Brain Metabolism, Increases Neurotransmitter Levels, and Improves Recovery
    Thuy-Vi V. Nguyen, Rachel H. Crumpacker, Kylie E. Calderon, Frankie G. Garcia, Jacob C. Zbesko, Jennifer B. Frye, Selena Gonzalez, Danielle A. Becktel, Tao Yang, Marco A. Tavera-Garcia, Helena W. Morrison, Rick G. Schnellmann, Frank M. Longo and Kristian P. Doyle
    Journal of Pharmacology and Experimental Therapeutics February 2022, 380 (2) 126-141; DOI: https://doi.org/10.1124/jpet.121.000711

Erratum

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    Correction to “Antinociceptive and Discriminative Stimulus Effects of Six Novel Psychoactive Opioid Substances in Male Rats”
    Journal of Pharmacology and Experimental Therapeutics February 2022, 380 (2) 142; DOI: https://doi.org/10.1124/jpet.121.000689err
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 380 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 380, Issue 2
1 Feb 2022
  • Table of Contents
  • Table of Contents (PDF)
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  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Metabolism, Transport, and Pharmacogenetics
  • Neuropharmacology
  • Erratum
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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