Journal of Pharmacology and Experimental Therapeutics: 380 (1)

January 01, 2022; Volume 380,Issue 1

Editorial

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A Message from the New Editor-in-Chief
Beverley Greenwood-Van Meerveld

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 92-93; DOI: https://doi.org/10.1124/jpet.121.000984

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The Role of Ruthenium Compounds in Neurologic Diseases: A Minireview
Fátima Virgínia Gama Justi, Gabriella Araújo Matos, Juan de Sá Roriz Caminha, Cássia Rodrigues Roque, Edinilton Muniz Carvalho, Márcio Wilker Soares Campelo, Ludmila Belayev, Luiz Gonzaga de França Lopes and Reinaldo Barreto Oriá

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 47-53; DOI: https://doi.org/10.1124/jpet.121.000798

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The Cannabinoid Receptor Type 1 Positive Allosteric Modulator ZCZ011 Attenuates Naloxone-Precipitated Diarrhea and Weight Loss in Oxycodone-Dependent Mice
Julien C. Dodu, Rebecca K. Moncayo, M. Imad Damaj, Joel E. Schlosburg, Hamid I. Akbarali, Lesley D. O’Brien, Debra A. Kendall, Zhixing Wu, Dai Lu and Aron H. Lichtman

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 1-14; DOI: https://doi.org/10.1124/jpet.121.000723

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A Putative New Melatonin Binding Site in Sheep Brain, MTx: Preliminary Observations and Characteristics
Preety Shabajee-Alibay, Anne Bonnaud, Benoît Malpaux, Philippe Delagrange, Valérie Audinot, Saïd Yous, Jean A. Boutin, Jean-Philippe Stephan, Jérôme Leprince and Céline Legros

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 76-89; DOI: https://doi.org/10.1124/jpet.121.000785

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Ixazomib Induces Apoptosis and Suppresses Proliferation in Esophageal Squamous Cell Carcinoma through Activation of the c-Myc/NOXA Pathway
Tianxiao Wang, Pengying Zhang, Lu Chen, Huijie Qi, Haifei Chen, Yongjun Zhu, Liudi Zhang, Mingkang Zhong, Xiaojin Shi and Qunyi Li

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 15-25; DOI: https://doi.org/10.1124/jpet.121.000837

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ASP7266, a Novel Antibody against Human Thymic Stromal Lymphopoietin Receptor for the Treatment of Allergic Diseases
Mako Numazaki, Masaki Abe, Kaori Hanaoka, Emiko Imamura, Masashi Maeda, Akihiko Kimura, Jun Miyanohara, Tetsu Saito, Kazunori Arai, Hiroshi Suzuki and Yuji Saita

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 26-33; DOI: https://doi.org/10.1124/jpet.121.000686
Open Access
Protein Kinase A–Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer Cells
Ilari Tarvainen, Rebecca C. Nunn, Raimo K. Tuominen, Maria H. Jäntti and Virpi Talman

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 54-62; DOI: https://doi.org/10.1124/jpet.121.000848

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Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity
Jessica I. Griffith, Minjee Kim, Daniel J. Bruce, Cristina D. Peterson, Kelley F. Kitto, Afroz S. Mohammad, Sneha Rathi, Carolyn A. Fairbanks, George L. Wilcox and William F. Elmquist

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 34-46; DOI: https://doi.org/10.1124/jpet.121.000821

Open Access
Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2
Yaotian Hu, Wenjing Zhou, Zhiyi Xue, Xuemeng Liu, Zichao Feng, Yulin Zhang, Xiaofei Liu, Wenjie Li, Qing Zhang, Anjing Chen, Bin Huang and Jian Wang

Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 63-75; DOI: https://doi.org/10.1124/jpet.121.000852