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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

January 01, 2022; Volume 380,Issue 1

Editorial

  • You have access
    A Message from the New Editor-in-Chief
    Beverley Greenwood-Van Meerveld
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 92-93; DOI: https://doi.org/10.1124/jpet.121.000984

Minireview

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    The Role of Ruthenium Compounds in Neurologic Diseases: A Minireview
    Fátima Virgínia Gama Justi, Gabriella Araújo Matos, Juan de Sá Roriz Caminha, Cássia Rodrigues Roque, Edinilton Muniz Carvalho, Márcio Wilker Soares Campelo, Ludmila Belayev, Luiz Gonzaga de França Lopes and Reinaldo Barreto Oriá
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 47-53; DOI: https://doi.org/10.1124/jpet.121.000798

Behavioral Pharmacology

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    The Cannabinoid Receptor Type 1 Positive Allosteric Modulator ZCZ011 Attenuates Naloxone-Precipitated Diarrhea and Weight Loss in Oxycodone-Dependent Mice
    Julien C. Dodu, Rebecca K. Moncayo, M. Imad Damaj, Joel E. Schlosburg, Hamid I. Akbarali, Lesley D. O’Brien, Debra A. Kendall, Zhixing Wu, Dai Lu and Aron H. Lichtman
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 1-14; DOI: https://doi.org/10.1124/jpet.121.000723

Cellular and Molecular

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    A Putative New Melatonin Binding Site in Sheep Brain, MTx: Preliminary Observations and Characteristics
    Preety Shabajee-Alibay, Anne Bonnaud, Benoît Malpaux, Philippe Delagrange, Valérie Audinot, Saïd Yous, Jean A. Boutin, Jean-Philippe Stephan, Jérôme Leprince and Céline Legros
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 76-89; DOI: https://doi.org/10.1124/jpet.121.000785

Chemotherapy, Antibiotics, and Gene Therapy

  • Ixazomib Induces Apoptosis and Suppresses Proliferation in Esophageal Squamous Cell Carcinoma through Activation of the c-Myc/NOXA Pathway
    You have access
    Ixazomib Induces Apoptosis and Suppresses Proliferation in Esophageal Squamous Cell Carcinoma through Activation of the c-Myc/NOXA Pathway
    Tianxiao Wang, Pengying Zhang, Lu Chen, Huijie Qi, Haifei Chen, Yongjun Zhu, Liudi Zhang, Mingkang Zhong, Xiaojin Shi and Qunyi Li
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 15-25; DOI: https://doi.org/10.1124/jpet.121.000837

Drug Discovery and Translational Medicine

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    ASP7266, a Novel Antibody against Human Thymic Stromal Lymphopoietin Receptor for the Treatment of Allergic Diseases
    Mako Numazaki, Masaki Abe, Kaori Hanaoka, Emiko Imamura, Masashi Maeda, Akihiko Kimura, Jun Miyanohara, Tetsu Saito, Kazunori Arai, Hiroshi Suzuki and Yuji Saita
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 26-33; DOI: https://doi.org/10.1124/jpet.121.000686
  • Open Access
    Protein Kinase A–Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer Cells
    Ilari Tarvainen, Rebecca C. Nunn, Raimo K. Tuominen, Maria H. Jäntti and Virpi Talman
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 54-62; DOI: https://doi.org/10.1124/jpet.121.000848

Metabolism, Transport, and Pharmacogenetics

  • Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity
    You have access
    Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity
    Jessica I. Griffith, Minjee Kim, Daniel J. Bruce, Cristina D. Peterson, Kelley F. Kitto, Afroz S. Mohammad, Sneha Rathi, Carolyn A. Fairbanks, George L. Wilcox and William F. Elmquist
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 34-46; DOI: https://doi.org/10.1124/jpet.121.000821

Neuropharmacology

  • Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2
    Open Access
    Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2
    Yaotian Hu, Wenjing Zhou, Zhiyi Xue, Xuemeng Liu, Zichao Feng, Yulin Zhang, Xiaofei Liu, Wenjie Li, Qing Zhang, Anjing Chen, Bin Huang and Jian Wang
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 63-75; DOI: https://doi.org/10.1124/jpet.121.000852

Erratum

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    Correction to “A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor ɣ with Excellent Effect on Insulin Resistance and Type 2 Diabetes”
    Journal of Pharmacology and Experimental Therapeutics January 2022, 380 (1) 90-91; DOI: https://doi.org/10.1124/jpet.115.223107err
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 380 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 380, Issue 1
1 Jan 2022
  • Table of Contents
  • Table of Contents (PDF)
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  • Editorial
  • Minireview
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  • Neuropharmacology
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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