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Research ArticleDrug Discovery and Translational Medicine
Open Access

Pharmacokinetics and Pharmacodynamic Effects of Nemvaleukin Alfa, a Selective Agonist of the Intermediate-Affinity IL-2 Receptor, in Cynomolgus Monkeys

Jared E. Lopes, Lei Sun, Heather L. Flick, Erin A. Murphy and Heather C. Losey
Journal of Pharmacology and Experimental Therapeutics November 2021, 379 (2) 203-210; DOI: https://doi.org/10.1124/jpet.121.000612
Jared E. Lopes
Alkermes, Inc., Waltham, Massachusetts
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Lei Sun
Alkermes, Inc., Waltham, Massachusetts
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Heather L. Flick
Alkermes, Inc., Waltham, Massachusetts
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Erin A. Murphy
Alkermes, Inc., Waltham, Massachusetts
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Heather C. Losey
Alkermes, Inc., Waltham, Massachusetts
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Article Information

vol. 379 no. 2 203-210
DOI 
https://doi.org/10.1124/jpet.121.000612
PubMed 
34362793

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received March 12, 2021
  • Accepted August 4, 2021
  • Published online November 12, 2021.

Article Versions

  • Earlier version (August 6, 2021 - 08:05).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license.

Author Information

  1. Jared E. Lopes,
  2. Lei Sun,
  3. Heather L. Flick,
  4. Erin A. Murphy, and
  5. Heather C. Losey
  1. Alkermes, Inc., Waltham, Massachusetts
  1. Address correspondence to:
    Heather C. Losey, Alkermes, Inc. 852 Winter St. Waltham, MA 02451. E-mail: heather.losey{at}alkermes.com
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Journal of Pharmacology and Experimental Therapeutics: 379 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 379, Issue 2
1 Nov 2021
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Research ArticleDrug Discovery and Translational Medicine

Pharmacology of Nemvaleukin Alfa in Cynomolgus Monkeys

Jared E. Lopes, Lei Sun, Heather L. Flick, Erin A. Murphy and Heather C. Losey
Journal of Pharmacology and Experimental Therapeutics November 1, 2021, 379 (2) 203-210; DOI: https://doi.org/10.1124/jpet.121.000612

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Research ArticleDrug Discovery and Translational Medicine

Pharmacology of Nemvaleukin Alfa in Cynomolgus Monkeys

Jared E. Lopes, Lei Sun, Heather L. Flick, Erin A. Murphy and Heather C. Losey
Journal of Pharmacology and Experimental Therapeutics November 1, 2021, 379 (2) 203-210; DOI: https://doi.org/10.1124/jpet.121.000612
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