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Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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  • Information
    • Instructions to Authors
    • Submit a Manuscript
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Index by author

March 01, 2021; Volume 376,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Ahlschwede, Kristen M.

    1. You have access
      Distinct Uptake Kinetics of Alzheimer Disease Amyloid-β 40 and 42 at the Blood-Brain Barrier Endothelium
      Nidhi Sharda, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe and Karunya K. Kandimalla
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 482-490; DOI: https://doi.org/10.1124/jpet.120.000086
  2. Ahmed-Belkacem, Abdelhakim

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
  3. Anderson, Mitchell

    1. Open Access
      Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
      Scott D. Barnett, Hazik Asif, Mitchell Anderson and Iain L. O. Buxton
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 444-453; DOI: https://doi.org/10.1124/jpet.120.000427
  4. Asai, Kuniya

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  5. Asif, Hazik

    1. Open Access
      Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
      Scott D. Barnett, Hazik Asif, Mitchell Anderson and Iain L. O. Buxton
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 444-453; DOI: https://doi.org/10.1124/jpet.120.000427

B

  1. Bai, Dongdong

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  2. Banks, M.L.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  3. Barnett, Scott D.

    1. Open Access
      Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
      Scott D. Barnett, Hazik Asif, Mitchell Anderson and Iain L. O. Buxton
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 444-453; DOI: https://doi.org/10.1124/jpet.120.000427
  4. Behm, David J.

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  5. Bender, Andrew T.

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  6. Borhegyi, Zsolt

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  7. Braun, Tobias

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  8. Buxton, Iain L. O.

    1. Open Access
      Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
      Scott D. Barnett, Hazik Asif, Mitchell Anderson and Iain L. O. Buxton
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 444-453; DOI: https://doi.org/10.1124/jpet.120.000427

C

  1. Cantrill, Carina

    1. You have access
      Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
      Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158
  2. Cao, Pingfeng

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  3. Chen, Dapeng

    1. You have access
      Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
      Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
  4. Chen, Lei

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  5. Costell, Melissa H.

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  6. Crowley, Morgan L.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  7. Curran, Geoffry L.

    1. You have access
      Distinct Uptake Kinetics of Alzheimer Disease Amyloid-β 40 and 42 at the Blood-Brain Barrier Endothelium
      Nidhi Sharda, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe and Karunya K. Kandimalla
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 482-490; DOI: https://doi.org/10.1124/jpet.120.000086

D

  1. Déri, Máté T.

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  2. Deshpande, Aditee

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  3. Diester, C.M.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  4. Ding, Zheng-Ming

    1. You have access
      Self-Administration of Cotinine in Wistar Rats: Comparisons to Nicotine
      Zheng-Ming Ding, Yong Gao, Alena M. Sentir and Xiaoying Tan
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 338-347; DOI: https://doi.org/10.1124/jpet.120.000367

F

  1. Farahanchi, Nazli

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  2. Farzaneh, Ted

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  3. Fischer, Holger

    1. You have access
      Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
      Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158
  4. Fortner, John D.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189

G

  1. Gamez-Jimenez, Lea R.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  2. Gao, Yong

    1. You have access
      Self-Administration of Cotinine in Wistar Rats: Comparisons to Nicotine
      Zheng-Ming Ding, Yong Gao, Alena M. Sentir and Xiaoying Tan
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 338-347; DOI: https://doi.org/10.1124/jpet.120.000367
  3. Ghaleh, Bijan

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
  4. Goodman, Krista

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  5. Goto, Masaki

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  6. Gou, Xiaoli

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  7. Goyal, Navin

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  8. Guichou, Jean-François

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
  9. Gyimesi, Máté

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167

H

  1. Hamada, Hiroki

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096
  2. Hamow, Kamirán Á.

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  3. Haselmayer, Philipp

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  4. Haslett, Patrick A.

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  5. Hibi, Chihiro

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  6. Hiranita, Takato

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  7. Ho, Nicholas P.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  8. Horio, Yoshiyuki

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096
  9. Hosoda, Ryusuke

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096

I

  1. Iseki, Yuzo

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  2. Iwahara, Naotoshi

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096

J

  1. Jali, A.M.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  2. James, Christian H.

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  3. Johnson, Theresa L.

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275

K

  1. Kamiya, Masataka

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  2. Kandimalla, Karunya K.

    1. You have access
      Distinct Uptake Kinetics of Alzheimer Disease Amyloid-β 40 and 42 at the Blood-Brain Barrier Endothelium
      Nidhi Sharda, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe and Karunya K. Kandimalla
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 482-490; DOI: https://doi.org/10.1124/jpet.120.000086
  3. Khanifar, Elham

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  4. Khazaeli, Mahyar

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  5. Kiss, Ádám F.

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  6. Komiyama, Hidenori

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  7. Kornya, László

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  8. Kovács, Mihály

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  9. Krans, Jacob

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  10. Kuno, Atsushi

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096
  11. Kurokawa, Junko

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290

L

  1. Legakis, L.P.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  2. León, Francisco

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  3. Li, Yao

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  4. Liang, Yong

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  5. Liu, Han

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  6. Lopera-Londoño, Carolina

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  7. Lőrincz, István

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  8. Lowe, Val J.

    1. You have access
      Distinct Uptake Kinetics of Alzheimer Disease Amyloid-β 40 and 42 at the Blood-Brain Barrier Endothelium
      Nidhi Sharda, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe and Karunya K. Kandimalla
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 482-490; DOI: https://doi.org/10.1124/jpet.120.000086

M

  1. Maejima, Yasuhiro

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  2. Maejima, Yuko

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  3. Málnási-Csizmadia, András

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  4. McCurdy, Christopher R.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  5. McMahon, Lance R.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  6. Mizuno, Kyoichi

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  7. Monostory, Katalin

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  8. Moradi, Hamid

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  9. Morin, Didier

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
  10. Morse, Noune Tahmassian

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  11. Mottinelli, Marco

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  12. Murai, Koji

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  13. Murakawa, Masahiro

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  14. Musil, Djordje

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275

N

  1. Nag, Suman

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  2. Negus, S.S.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  3. Ni, Jia

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  4. Nojima, Iyori

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096
  5. Noma, Satsuki

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140

O

  1. Obeng, Samuel

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  2. Okitsu, Shinji L.

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  3. Ono, Yuko

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  4. Oravecz, Kinga

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167

P

  1. Pallares, Victoria L.C.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  2. Panel, Mathieu

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
  3. Patel, Avi

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  4. Patterson, Jaclyn

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  5. Pawlotsky, Jean-Michel

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359
  6. Pennington, Anna E.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  7. Pereira, Albertina

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  8. Przetak, Melinda

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275

Q

  1. Qian, Meilin

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315

R

  1. Rauscher, Anna Á.

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  2. Reeves, Morgan E.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  3. Reissig, Sonja

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  4. Restrepo, Luis F.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  5. Roethke, Theresa

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  6. Ruiz, Isaac

    1. You have access
      A Phenyl-Pyrrolidine Derivative Reveals a Dual Inhibition Mechanism of Myocardial Mitochondrial Permeability Transition Pore, Which Is Limited by Its Myocardial Distribution
      Mathieu Panel, Abdelhakim Ahmed-Belkacem, Isaac Ruiz, Jean-François Guichou, Jean-Michel Pawlotsky, Bijan Ghaleh and Didier Morin
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 348-357; DOI: https://doi.org/10.1124/jpet.120.000359

S

  1. Sakamoto, Kazuho

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  2. Santos, E.J.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  3. Sato, Naoki

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  4. Schuler, Franz

    1. You have access
      Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
      Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158
  5. Selley, D.E.

    1. You have access
      Manipulating Pharmacodynamic Efficacy with Agonist + Antagonist Mixtures: In Vitro and In Vivo Studies with Opioids and Cannabinoids
      D.E. Selley, M.L. Banks, C.M. Diester, A.M. Jali, L.P. Legakis, E.J. Santos and S.S. Negus
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 374-384; DOI: https://doi.org/10.1124/jpet.120.000349
  6. Senn, Claudia

    1. You have access
      Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
      Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158
  7. Sentir, Alena M.

    1. You have access
      Self-Administration of Cotinine in Wistar Rats: Comparisons to Nicotine
      Zheng-Ming Ding, Yong Gao, Alena M. Sentir and Xiaoying Tan
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 338-347; DOI: https://doi.org/10.1124/jpet.120.000367
  8. Sharda, Nidhi

    1. You have access
      Distinct Uptake Kinetics of Alzheimer Disease Amyloid-β 40 and 42 at the Blood-Brain Barrier Endothelium
      Nidhi Sharda, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe and Karunya K. Kandimalla
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 482-490; DOI: https://doi.org/10.1124/jpet.120.000086
  9. Sherer, Brian

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  10. Shi, Zongjun

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  11. Shimizu, Wataru

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  12. Shimomura, Kenju

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  13. Shirakabe, Akihiro

    1. You have access
      β3-Adrenergic Receptor Agonist Prevents Diastolic Dysfunction in an Angiotensin II–Induced Cardiomyopathy Mouse Model
      Masataka Kamiya, Kuniya Asai, Yasuhiro Maejima, Akihiro Shirakabe, Koji Murai, Satsuki Noma, Hidenori Komiyama, Naoki Sato, Kyoichi Mizuno and Wataru Shimizu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 473-481; DOI: https://doi.org/10.1124/jpet.120.000140
  14. Soundarapandian, Mangala M.

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  15. Sprecher, Dennis L.

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  16. Stoy, Patrick

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  17. Sun, Jia’ao

    1. You have access
      Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
      Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
  18. Suthar, Sharad Kumar

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  19. Szabó, Pál Tamás

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167

T

  1. Takeshita, Shunya

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  2. Tan, Bowei

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  3. Tan, Xiaoying

    1. You have access
      Self-Administration of Cotinine in Wistar Rats: Comparisons to Nicotine
      Zheng-Ming Ding, Yong Gao, Alena M. Sentir and Xiaoying Tan
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 338-347; DOI: https://doi.org/10.1124/jpet.120.000367
  4. Tanaka, Shoko

    1. Opening of Intermediate Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      You have access
      Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway
      Yuzo Iseki, Yuko Ono, Chihiro Hibi, Shoko Tanaka, Shunya Takeshita, Yuko Maejima, Junko Kurokawa, Masahiro Murakawa, Kenju Shimomura and Kazuho Sakamoto
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 454-462; DOI: https://doi.org/10.1124/jpet.120.000290
  5. Taylor, Victoria A.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  6. Thorneloe, Kevin S.

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307
  7. Tierney, Patrick J.

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  8. Tomasic, Ivan

    1. Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Open Access
      Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2
      Máté Gyimesi, Anna Á. Rauscher, Sharad Kumar Suthar, Kamirán Á. Hamow, Kinga Oravecz, István Lőrincz, Zsolt Borhegyi, Máté T. Déri, Ádám F. Kiss, Katalin Monostory, Pál Tamás Szabó, Suman Nag, Ivan Tomasic, Jacob Krans, Patrick J. Tierney, Mihály Kovács, László Kornya and András Málnási-Csizmadia
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 358-373; DOI: https://doi.org/10.1124/jpet.120.000167
  9. Tzvetkov, Evgeni

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275

U

  1. Uesugi, Daisuke

    1. You have access
      Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol
      Ryusuke Hosoda, Hiroki Hamada, Daisuke Uesugi, Naotoshi Iwahara, Iyori Nojima, Yoshiyuki Horio and Atsushi Kuno
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 385-396; DOI: https://doi.org/10.1124/jpet.120.000096
  2. Ullah, Mohammed

    1. You have access
      Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
      Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158

V

  1. Vaziri, Nosratola D.

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  2. Vlach, Jaromir

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275

W

  1. Walsky, Robert L.

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
  2. Wang, Liang

    1. You have access
      Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
      Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
  3. Wilkerson, Jenny L.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189
  4. Williamson, Morgan R.

    1. You have access
      Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
      Samuel Obeng, Jenny L. Wilkerson, Francisco León, Morgan E. Reeves, Luis F. Restrepo, Lea R. Gamez-Jimenez, Avi Patel, Anna E. Pennington, Victoria A. Taylor, Nicholas P. Ho, Tobias Braun, John D. Fortner, Morgan L. Crowley, Morgan R. Williamson, Victoria L.C. Pallares, Marco Mottinelli, Carolina Lopera-Londoño, Christopher R. McCurdy, Lance R. McMahon and Takato Hiranita
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 410-427; DOI: https://doi.org/10.1124/jpet.120.000189

X

  1. Xiong, Yongjian

    1. You have access
      Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
      Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
  2. Xu, Xiaoping

    1. You have access
      Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
      Xiaoping Xu, Navin Goyal, Melissa H. Costell, Theresa Roethke, Christian H. James, Kevin S. Thorneloe, Jaclyn Patterson, Patrick Stoy, Krista Goodman, Dennis L. Sprecher and David J. Behm
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 436-443; DOI: https://doi.org/10.1124/jpet.120.000307

Y

  1. Ye, Fei

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  2. Yu, Li

    1. You have access
      Calculation of an Apical Efflux Ratio from P-Glycoprotein (P-gp) In Vitro Transport Experiments Shows an Improved Correlation with In Vivo Cerebrospinal Fluid Measurements in Rats: Impact on P-gp Screening and Compound Optimization
      Holger Fischer, Claudia Senn, Mohammed Ullah, Carina Cantrill, Franz Schuler and Li Yu
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 322-329; DOI: https://doi.org/10.1124/jpet.120.000158
  3. Yu, Xiaojuan

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315

Z

  1. Zhang, Chi

    1. You have access
      Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
      Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
  2. Zhang, Guolin

    1. You have access
      Phytochemical Regulation of RNA in Treating Inflammatory Bowel Disease and Colon Cancer: Inspirations from Cell and Animal Studies
      Guolin Zhang, Chi Zhang, Jia’ao Sun, Yongjian Xiong, Liang Wang and Dapeng Chen
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 464-472; DOI: https://doi.org/10.1124/jpet.120.000354
  3. Zhao, Yitong

    1. You have access
      RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia
      Yitong Zhao, Masaki Goto, Nosratola D. Vaziri, Mahyar Khazaeli, Han Liu, Nazli Farahanchi, Elham Khanifar, Ted Farzaneh, Patrick A. Haslett, Hamid Moradi and Mangala M. Soundarapandian
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 428-435; DOI: https://doi.org/10.1124/jpet.120.000257
  4. Zheng, Xiaoxiao

    1. You have access
      Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
      Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang and Jia Ni
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 330-337; DOI: https://doi.org/10.1124/jpet.120.000315
  5. Zimmerli, Simone C.

    1. Open Access
      Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
      Jaromir Vlach, Andrew T. Bender, Melinda Przetak, Albertina Pereira, Aditee Deshpande, Theresa L. Johnson, Sonja Reissig, Evgeni Tzvetkov, Djordje Musil, Noune Tahmassian Morse, Philipp Haselmayer, Simone C. Zimmerli, Shinji L. Okitsu, Robert L. Walsky and Brian Sherer
      Journal of Pharmacology and Experimental Therapeutics March 2021, 376 (3) 397-409; DOI: https://doi.org/10.1124/jpet.120.000275
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Journal of Pharmacology and Experimental Therapeutics: 376 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 3
1 Mar 2021
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