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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Lysosomal Biogenesis and Implications for Hydroxychloroquine Disposition

Keagan P. Collins, Sandra Witta, Jonathan W. Coy, Yi Pang and Daniel L. Gustafson
Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 294-305; DOI: https://doi.org/10.1124/jpet.120.000309
Keagan P. Collins
Colorado State University, School of Biomedical Engineering (K.P.C., S.W., D.L.G.) and Department of Clinical Sciences (D.L.G., J.W.C.), Colorado State University, Fort Collins, Colorado; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado (D.L.G.); and University of Akron, Department of Chemistry, Akron, Ohio (Y.P.)
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Sandra Witta
Colorado State University, School of Biomedical Engineering (K.P.C., S.W., D.L.G.) and Department of Clinical Sciences (D.L.G., J.W.C.), Colorado State University, Fort Collins, Colorado; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado (D.L.G.); and University of Akron, Department of Chemistry, Akron, Ohio (Y.P.)
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Jonathan W. Coy
Colorado State University, School of Biomedical Engineering (K.P.C., S.W., D.L.G.) and Department of Clinical Sciences (D.L.G., J.W.C.), Colorado State University, Fort Collins, Colorado; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado (D.L.G.); and University of Akron, Department of Chemistry, Akron, Ohio (Y.P.)
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Yi Pang
Colorado State University, School of Biomedical Engineering (K.P.C., S.W., D.L.G.) and Department of Clinical Sciences (D.L.G., J.W.C.), Colorado State University, Fort Collins, Colorado; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado (D.L.G.); and University of Akron, Department of Chemistry, Akron, Ohio (Y.P.)
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Daniel L. Gustafson
Colorado State University, School of Biomedical Engineering (K.P.C., S.W., D.L.G.) and Department of Clinical Sciences (D.L.G., J.W.C.), Colorado State University, Fort Collins, Colorado; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado (D.L.G.); and University of Akron, Department of Chemistry, Akron, Ohio (Y.P.)
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Article Information

vol. 376 no. 2 294-305
DOI 
https://doi.org/10.1124/jpet.120.000309
PubMed 
33172973

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 28, 2020
  • Accepted October 26, 2020
  • Published online January 26, 2021.

Article Versions

  • Earlier version (November 10, 2020 - 11:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Keagan P. Collins,
  2. Sandra Witta,
  3. Jonathan W. Coy,
  4. Yi Pang, and
  5. Daniel L. Gustafson
  1. Colorado State University, School of Biomedical Engineering (K.P.C., S.W., D.L.G.) and Department of Clinical Sciences (D.L.G., J.W.C.), Colorado State University, Fort Collins, Colorado; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado (D.L.G.); and University of Akron, Department of Chemistry, Akron, Ohio (Y.P.)
  1. Address correspondence to:
    Dr. Daniel L. Gustafson, Flint Animal Cancer Center, 300 West Drake Rd., FACC246, Fort Collins, CO 80523. E-mail: daniel.gustafson{at}colostate.edu
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Article usage: November 2020 to April 2021

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Dec 202082074
Jan 202121015079
Feb 202114027027
Mar 2021851429
Apr 20212917

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Journal of Pharmacology and Experimental Therapeutics: 376 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 2
1 Feb 2021
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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Lysosomal Biogenesis and Hydroxychloroquine Disposition

Keagan P. Collins, Sandra Witta, Jonathan W. Coy, Yi Pang and Daniel L. Gustafson
Journal of Pharmacology and Experimental Therapeutics February 1, 2021, 376 (2) 294-305; DOI: https://doi.org/10.1124/jpet.120.000309

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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Lysosomal Biogenesis and Hydroxychloroquine Disposition

Keagan P. Collins, Sandra Witta, Jonathan W. Coy, Yi Pang and Daniel L. Gustafson
Journal of Pharmacology and Experimental Therapeutics February 1, 2021, 376 (2) 294-305; DOI: https://doi.org/10.1124/jpet.120.000309
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