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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

February 01, 2021; Volume 376,Issue 2

Minireview

  • Open Access
    The Pharmacological Case for Cannabigerol
    Rahul Nachnani, Wesley M. Raup-Konsavage and Kent E. Vrana
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 204-212; DOI: https://doi.org/10.1124/jpet.120.000340

Cardiovascular

  • You have access
    Specific Lowering of Asymmetric Dimethylarginine by Pharmacological Dimethylarginine Dimethylaminohydrolase Improves Endothelial Function, Reduces Blood Pressure and Ischemia-Reperfusion Injury
    Young Lee, Purvi Mehrotra, David Basile, Mahbub Ullah, Arshnoor Singh, Nicholas Skill, Subhi Talal Younes, Jennifer Sasser, Anantha Shekhar and Jaipal Singh
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 181-189; DOI: https://doi.org/10.1124/jpet.120.000212
  • You have access
    Mast Cell Degranulation Increases Mouse Mast Cell Protease 4–Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin I
    Laurence Vincent, Catherine Lapointe, Modou Lo, Hugo Gagnon, Gunnar Pejler, Shinji Takai, Robert Day and Pedro D’Orléans-Juste
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 213-221; DOI: https://doi.org/10.1124/jpet.120.000325
  • Predictors of Early or Delayed Diastolic Dysfunction After Anthracycline-Based or Nonanthracycline Chemotherapy: A Pharmacological Appraisal
    You have access
    Predictors of Early or Delayed Diastolic Dysfunction After Anthracycline-Based or Nonanthracycline Chemotherapy: A Pharmacological Appraisal
    Giorgio Minotti, Pierantonio Menna, Massimiliano Camilli, Emanuela Salvatorelli and Giorgio Reggiardo
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 231-239; DOI: https://doi.org/10.1124/jpet.120.000323

Chemotherapy, Antibiotics, and Gene Therapy

  • You have access
    Lysosomal Biogenesis and Implications for Hydroxychloroquine Disposition
    Keagan P. Collins, Sandra Witta, Jonathan W. Coy, Yi Pang and Daniel L. Gustafson
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 294-305; DOI: https://doi.org/10.1124/jpet.120.000309

Endocrine and Diabetes

  • You have access
    The Novel Phosphate and Bile Acid Sequestrant Polymer SAR442357 Delays Disease Progression in a Rat Model of Diabetic Nephropathy
    Tamara R. Castañeda, María Méndez, Ian Davison, Ralf Elvert, Uwe Schwahn, Galina Boldina, Corinne Rocher, Petra Scherer, Kuldeep Singh, Dinesh S. Bangari, Mechthilde Falkenhahn, Aimo Kannt, Anish Konkar, Philip J. Larsen, Cynthia Arbeeny, Pradeep K. Dhal and Thomas Hübschle
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 190-203; DOI: https://doi.org/10.1124/jpet.120.000285

Gastrointestinal, Hepatic, Pulmonary, and Renal

  • You have access
    Increased Levels of Renal Lysophosphatidic Acid in Rodent Models with Renal Disease
    Takashi Hirata, Stanley V. Smith, Teisuke Takahashi, Noriyuki Miyata and Richard J. Roman
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 240-249; DOI: https://doi.org/10.1124/jpet.120.000353
  • You have access
    Downregulation of the αvβ6 Integrin via RGD Engagement Is Affinity and Time Dependent
    James A. Roper, Alex L. Wilkinson, Elaine Gower and Robert J. Slack
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 273-280; DOI: https://doi.org/10.1124/jpet.120.000379
  • Activation of the G Protein–Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell
    Open Access
    Activation of the G Protein–Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell
    Qian Wang, Zhao Li, Kaixuan Liu, Jianbo Liu, Shiquan Chai, Guanyu Chen, Shuyu Wen, Tian Ming, Jiayi Wang, Yuntao Ma, Honghui Zeng, Chuanyong Liu and Bing Xue
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 281-293; DOI: https://doi.org/10.1124/jpet.120.000216

Inflammation, Immunopharmacology, and Asthma

  • You have access
    Prostanoid Receptors of the EP4-Subtype Mediate Gene Expression Changes in Human Airway Epithelial Cells with Potential Anti-Inflammatory Activity
    Radhika Joshi, Omar Hamed, Dong Yan, Aubrey N. Michi, Mahmoud M. Mostafa, Shahina Wiehler, Robert Newton and Mark A. Giembycz
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 161-180; DOI: https://doi.org/10.1124/jpet.120.000196
  • You have access
    Fingolimod Phosphate (FTY720-P) Activates Protein Phosphatase 2A in Human Monocytes and Inhibits Monosodium Urate Crystal–Induced Interleukin-1β Production
    Marwa Qadri, Sandy ElSayed and Khaled A. Elsaid
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 222-230; DOI: https://doi.org/10.1124/jpet.120.000321
  • Open Access
    Sphingosine 1-Phosphate Receptor Modulator ONO-4641 Regulates Trafficking of T Lymphocytes and Hematopoietic Stem Cells and Alleviates Immune-Mediated Aplastic Anemia in a Mouse Model
    Takaki Komiya, Masashi Gohda, Hiroki Shioya and Seishi Katsumata
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 250-260; DOI: https://doi.org/10.1124/jpet.120.000277

Metabolism, Transport, and Pharmacogenetics

  • You have access
    Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor-β Signaling in Human Endothelial Cells
    Patrick T. Ronaldson, Hrvoje Brzica, Wazir Abdullahi, Bianca G. Reilly and Thomas P. Davis
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 148-160; DOI: https://doi.org/10.1124/jpet.120.000267
  • You have access
    Physiologically Based Pharmacokinetics of Lysosomotropic Chloroquine in Rat and Human
    Xin Liu and William J. Jusko
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 261-272; DOI: https://doi.org/10.1124/jpet.120.000385

Neuropharmacology

  • Pharmacological Actions of Carbamate Insecticides at Mammalian Melatonin Receptors
    You have access
    Pharmacological Actions of Carbamate Insecticides at Mammalian Melatonin Receptors
    Grant C. Glatfelter, Anthony J. Jones, Rajendram V. Rajnarayanan and Margarita L. Dubocovich
    Journal of Pharmacology and Experimental Therapeutics February 2021, 376 (2) 306-321; DOI: https://doi.org/10.1124/jpet.120.000065
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Journal of Pharmacology and Experimental Therapeutics: 376 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 2
1 Feb 2021
  • Table of Contents
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