Research ArticleDrug Discovery and Translational Medicine
Open Access
Mechanistic Analysis of an Extracellular Signal–Regulated Kinase 2–Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress
Ramon Martinez III, Weiliang Huang, Ramin Samadani, Bryan Mackowiak, Garrick Centola, Lijia Chen, Ivie L. Conlon, Kellie Hom, Maureen A. Kane, Steven Fletcher and Paul Shapiro
Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 84-97; DOI: https://doi.org/10.1124/jpet.120.000266
Ramon Martinez III
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Weiliang Huang
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Ramin Samadani
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Bryan Mackowiak
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Garrick Centola
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Lijia Chen
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Ivie L. Conlon
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Kellie Hom
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Maureen A. Kane
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Steven Fletcher
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland
Paul Shapiro
Department of Pharmaceutical Sciences, University of Maryland, Baltimore- School of Pharmacy, Baltimore, Maryland

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Mechanisms of a Novel Inhibitor of Active ERK1/2 Signaling
Ramon Martinez, Weiliang Huang, Ramin Samadani, Bryan Mackowiak, Garrick Centola, Lijia Chen, Ivie L. Conlon, Kellie Hom, Maureen A. Kane, Steven Fletcher and Paul Shapiro
Journal of Pharmacology and Experimental Therapeutics January 1, 2021, 376 (1) 84-97; DOI: https://doi.org/10.1124/jpet.120.000266
Research ArticleDrug Discovery and Translational Medicine
Mechanisms of a Novel Inhibitor of Active ERK1/2 Signaling
Ramon Martinez, Weiliang Huang, Ramin Samadani, Bryan Mackowiak, Garrick Centola, Lijia Chen, Ivie L. Conlon, Kellie Hom, Maureen A. Kane, Steven Fletcher and Paul Shapiro
Journal of Pharmacology and Experimental Therapeutics January 1, 2021, 376 (1) 84-97; DOI: https://doi.org/10.1124/jpet.120.000266