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Research ArticleCardiovascular
Open Access

KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema

Brittney R. Garner, Amanda J. Stolarz, Daniel Stuckey, Mustafa Sarimollaoglu, Yunmeng Liu, Philip T. Palade, Nancy J. Rusch and Shengyu Mu
Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 40-50; DOI: https://doi.org/10.1124/jpet.120.000121
Brittney R. Garner
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Amanda J. Stolarz
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Daniel Stuckey
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Mustafa Sarimollaoglu
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Yunmeng Liu
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Philip T. Palade
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Nancy J. Rusch
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Shengyu Mu
Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Article Information

vol. 376 no. 1 40-50
DOI 
https://doi.org/10.1124/jpet.120.000121
PubMed 
33100270

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 21, 2020
  • Accepted October 8, 2020
  • Published online December 11, 2020.

Article Versions

  • Earlier version (October 25, 2020 - 01:05).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2020 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license.

Author Information

  1. Brittney R. Garner,
  2. Amanda J. Stolarz,
  3. Daniel Stuckey,
  4. Mustafa Sarimollaoglu,
  5. Yunmeng Liu,
  6. Philip T. Palade,
  7. Nancy J. Rusch, and
  8. Shengyu Mu
  1. Department of Pharmacology and Toxicology (B.R.G., A.J.S., D.S., Y.L., P.T.P., N.J.R., S.M.) and Arkansas Nanomedicine Center (M.S.), College of Medicine and Department of Pharmaceutical Sciences, College of Pharmacy (A.J.S.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
  1. Address correspondence to:
    Dr. Shengyu Mu, Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, 4301 W. Markham St., #611, Little Rock, AR 72205-7199. E-mail: smu{at}uams.edu
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Dec 20203618360
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Feb 2021186036

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Journal of Pharmacology and Experimental Therapeutics: 376 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 1
1 Jan 2021
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Research ArticleCardiovascular

KATP Channel Openers Inhibit Lymphatic Contractions and Flow

Brittney R. Garner, Amanda J. Stolarz, Daniel Stuckey, Mustafa Sarimollaoglu, Yunmeng Liu, Philip T. Palade, Nancy J. Rusch and Shengyu Mu
Journal of Pharmacology and Experimental Therapeutics January 1, 2021, 376 (1) 40-50; DOI: https://doi.org/10.1124/jpet.120.000121

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Research ArticleCardiovascular

KATP Channel Openers Inhibit Lymphatic Contractions and Flow

Brittney R. Garner, Amanda J. Stolarz, Daniel Stuckey, Mustafa Sarimollaoglu, Yunmeng Liu, Philip T. Palade, Nancy J. Rusch and Shengyu Mu
Journal of Pharmacology and Experimental Therapeutics January 1, 2021, 376 (1) 40-50; DOI: https://doi.org/10.1124/jpet.120.000121
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