Inhibiting Sialidase-Induced TGF-β1 Activation Attenuates Pulmonary Fibrosis in Mice

Tejas R. Karhadkar; Thomas D. Meek; Richard H. Gomer

doi:10.1124/jpet.120.000258

Research ArticleDrug Discovery and Translational Medicine

Inhibiting Sialidase-Induced TGF-β1 Activation Attenuates Pulmonary Fibrosis in Mice

Tejas R. Karhadkar, Thomas D. Meek and Richard H. Gomer

Journal of Pharmacology and Experimental Therapeutics January 2021, 376 (1) 106-117; DOI: https://doi.org/10.1124/jpet.120.000258

Tejas R. Karhadkar

Departments of Biology (T.R.K., R.H.G.) and Biochemistry and Biophysics (T.D.M.), Texas A&M University, College Station, Texas

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Thomas D. Meek

Departments of Biology (T.R.K., R.H.G.) and Biochemistry and Biophysics (T.D.M.), Texas A&M University, College Station, Texas

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Richard H. Gomer

Departments of Biology (T.R.K., R.H.G.) and Biochemistry and Biophysics (T.D.M.), Texas A&M University, College Station, Texas

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Journal of Pharmacology and Experimental Therapeutics

Vol. 376, Issue 1

1 Jan 2021

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Research ArticleDrug Discovery and Translational Medicine