Journal of Pharmacology and Experimental Therapeutics: 375 (2)

November 01, 2020; Volume 375,Issue 2

Minireview

You have access
Strategies for Developing κ Opioid Receptor Agonists for the Treatment of Pain with Fewer Side Effects
Kelly F. Paton, Diana V. Atigari, Sophia Kaska, Thomas Prisinzano and Bronwyn M. Kivell

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 332-348; DOI: https://doi.org/10.1124/jpet.120.000134

Behavioral Pharmacology

You have access
Mifepristone Decreases Chronic Voluntary Ethanol Consumption in Rhesus Macaques
Vanessa A. Jimenez, Nicole A.R. Walter, Tatiana A. Shnitko, Natali Newman, Kaya Diem, Lauren Vanderhooft, Hazel Hunt and Kathleen A. Grant

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 258-267; DOI: https://doi.org/10.1124/jpet.120.000169

Cardiovascular

You have access
Protective Mechanism of the Selective Vasopressin V_1A Receptor Agonist Selepressin against Endothelial Barrier Dysfunction
Nektarios Barabutis, Margarita Marinova, Pavel Solopov, Mohammad A. Uddin, Glenn E. Croston, Torsten M. Reinheimer and John D. Catravas

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 286-295; DOI: https://doi.org/10.1124/jpet.120.000146
You have access
Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post–Myocardial Infarction Remodeling
David C. Lobb, Heather Doviak, Gregory L. Brower, Eva Romito, Jason W. O’Neill, Stephen Smith, James A. Shuman, Parker D. Freels, Kia N. Zellars, Lisa A. Freeburg, Aarif Y. Khakoo, TaeWeon Lee and Francis G. Spinale

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 296-307; DOI: https://doi.org/10.1124/jpet.120.000047

Drug Discovery and Translational Medicine

You have access
Celastrol Dilates and Counteracts Ethanol-Induced Constriction of Cerebral Arteries
Kelsey North, Alexandria Slayden, Steven Mysiewicz, Anna Bukiya and Alex Dopico

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 247-257; DOI: https://doi.org/10.1124/jpet.120.000152
You have access
Angiotensin-(1–7) Rescues Chronic Intermittent Hypoxia-Aggravated Transforming Growth Factor-β–Mediated Airway Remodeling in Murine and Cellular Models of Asthma
Jian Ping Zhou, Ying Ni Lin, Ning Li, Xian Wen Sun, Yong Jie Ding, Ya Ru Yan, Liu Zhang and Qing Yun Li

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 268-275; DOI: https://doi.org/10.1124/jpet.120.000150
You have access
Effects of Topical Application of CHF6467, a Mutated Form of Human Nerve Growth Factor, on Skin Wound Healing in Diabetic Mice
A. Giuliani, L. Lorenzini, V.A. Baldassarro, M. Pannella, M. Cescatti, M. Fernandez, G. Alastra, A. Flagelli, G. Villetti, B.P. Imbimbo, L. Giardino and L. Calzà

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 317-331; DOI: https://doi.org/10.1124/jpet.120.000110
Open Access
Utilizing Designed Receptors Exclusively Activated by Designer Drug Chemogenetic Tools to Identify Beneficial G Protein–Coupled Receptor Signaling for Fibrosis
Ji Zhang, Eyal Vardy, Eric S. Muise, Tzu-Ming Wang, Richard Visconti, Ashita Vadlamudi, Shirly Pinto and Andrea M. Peier

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 357-366; DOI: https://doi.org/10.1124/jpet.120.000103
You have access
GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain
Kathryn Braden, Luigino Antonio Giancotti, Zhoumou Chen, Chelsea DeLeon, Nick Latzo, Terri Boehm, Napoleon D’Cunha, Bonne M. Thompson, Timothy M. Doyle, Jeffrey G. McDonald, John K. Walker, Grant R. Kolar, Christopher Kent Arnatt and Daniela Salvemini

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 367-375; DOI: https://doi.org/10.1124/jpet.120.000105

Metabolism, Transport, and Pharmacogenomics

You have access
High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid-β Distribution between Brain and Plasma
Suresh K. Swaminathan, Andrew L. Zhou, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe, Ling Li and Karunya K. Kandimalla

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 308-316; DOI: https://doi.org/10.1124/jpet.120.265876
You have access
Ezetimibe Enhances Macrophage-to-Feces Reverse Cholesterol Transport in Golden Syrian Hamsters Fed a High-Cholesterol Diet
Fatima Kasbi-Chadli, Morgan Treguier, François Briand, Thierry Sulpice and Khadija Ouguerram

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 349-356; DOI: https://doi.org/10.1124/jpet.120.000062
You have access
Physiologically Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats
Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 385-396; DOI: https://doi.org/10.1124/jpet.120.000191

Neuropharmacology

You have access
A Novel Potent and Selective Histamine H₃ Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, and Wake-Promoting and Procognitive Effects in Rodents
Noriko Hino, Toshiyuki Marumo, Makiko Kotani, Toshiharu Shimazaki, Ayaka Kaku-Fukumoto, Hirohiko Hikichi, Jun-ichi Karasawa, Yasumitsu Tomishima, Hiroko Komiyama, Emi Tatsuda, Dai Nozawa, Toshio Nakamura and Shigeyuki Chaki

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 276-285; DOI: https://doi.org/10.1124/jpet.120.000185
You have access
Association Between N-Desmethylclozapine and Clozapine-Induced Sialorrhea: Involvement of Increased Nocturnal Salivary Secretion via Muscarinic Receptors by N-Desmethylclozapine
Shuhei Ishikawa, Masaki Kobayashi, Naoki Hashimoto, Hideaki Mikami, Akihiko Tanimura, Katsuya Narumi, Ayako Furugen, Ichiro Kusumi and Ken Iseki

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 376-384; DOI: https://doi.org/10.1124/jpet.120.000164

Toxicology

You have access
Untargeted Metabolomics Reveals Anaerobic Glycolysis as a Novel Target of the Hepatotoxic Antidepressant Nefazodone
Evelin Krajnc, Michele Visentin, Zhibo Gai, Bruno Stieger, Sophia L. Samodelov, Stephanie Häusler and Gerd A. Kullak-Ublick

Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 239-246; DOI: https://doi.org/10.1124/jpet.120.000120

Notice of Retraction

You have access
Notice of Retraction: Harada S, Yamazaki Y, and Tokuyama S (2013) Orexin-A Suppresses Postischemic Glucose Intolerance and Neuronal Damage through Hypothalamic Brain-Derived Neurotrophic Factor, J Pharmacol Exp Ther, 344: 276-285; DOI: https://doi.org/10.1124/jpet.112.199604
Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 397; DOI: https://doi.org/10.1124/jpet.112.199604retraction

Main menu

User menu

Search

Table of Contents

Minireview

Behavioral Pharmacology

Cardiovascular

Drug Discovery and Translational Medicine

Metabolism, Transport, and Pharmacogenomics

Neuropharmacology

Toxicology

Notice of Retraction

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals