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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

November 01, 2020; Volume 375,Issue 2

Minireview

  • You have access
    Strategies for Developing κ Opioid Receptor Agonists for the Treatment of Pain with Fewer Side Effects
    Kelly F. Paton, Diana V. Atigari, Sophia Kaska, Thomas Prisinzano and Bronwyn M. Kivell
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 332-348; DOI: https://doi.org/10.1124/jpet.120.000134

Behavioral Pharmacology

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    Mifepristone Decreases Chronic Voluntary Ethanol Consumption in Rhesus Macaques
    Vanessa A. Jimenez, Nicole A.R. Walter, Tatiana A. Shnitko, Natali Newman, Kaya Diem, Lauren Vanderhooft, Hazel Hunt and Kathleen A. Grant
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 258-267; DOI: https://doi.org/10.1124/jpet.120.000169

Cardiovascular

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    Protective Mechanism of the Selective Vasopressin V1A Receptor Agonist Selepressin against Endothelial Barrier Dysfunction
    Nektarios Barabutis, Margarita Marinova, Pavel Solopov, Mohammad A. Uddin, Glenn E. Croston, Torsten M. Reinheimer and John D. Catravas
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 286-295; DOI: https://doi.org/10.1124/jpet.120.000146
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    Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post–Myocardial Infarction Remodeling
    David C. Lobb, Heather Doviak, Gregory L. Brower, Eva Romito, Jason W. O’Neill, Stephen Smith, James A. Shuman, Parker D. Freels, Kia N. Zellars, Lisa A. Freeburg, Aarif Y. Khakoo, TaeWeon Lee and Francis G. Spinale
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 296-307; DOI: https://doi.org/10.1124/jpet.120.000047

Drug Discovery and Translational Medicine

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    Celastrol Dilates and Counteracts Ethanol-Induced Constriction of Cerebral Arteries
    Kelsey North, Alexandria Slayden, Steven Mysiewicz, Anna Bukiya and Alex Dopico
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 247-257; DOI: https://doi.org/10.1124/jpet.120.000152
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    Angiotensin-(1–7) Rescues Chronic Intermittent Hypoxia-Aggravated Transforming Growth Factor-β–Mediated Airway Remodeling in Murine and Cellular Models of Asthma
    Jian Ping Zhou, Ying Ni Lin, Ning Li, Xian Wen Sun, Yong Jie Ding, Ya Ru Yan, Liu Zhang and Qing Yun Li
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 268-275; DOI: https://doi.org/10.1124/jpet.120.000150
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    Effects of Topical Application of CHF6467, a Mutated Form of Human Nerve Growth Factor, on Skin Wound Healing in Diabetic Mice
    A. Giuliani, L. Lorenzini, V.A. Baldassarro, M. Pannella, M. Cescatti, M. Fernandez, G. Alastra, A. Flagelli, G. Villetti, B.P. Imbimbo, L. Giardino and L. Calzà
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 317-331; DOI: https://doi.org/10.1124/jpet.120.000110
  • Open Access
    Utilizing Designed Receptors Exclusively Activated by Designer Drug Chemogenetic Tools to Identify Beneficial G Protein–Coupled Receptor Signaling for Fibrosis
    Ji Zhang, Eyal Vardy, Eric S. Muise, Tzu-Ming Wang, Richard Visconti, Ashita Vadlamudi, Shirly Pinto and Andrea M. Peier
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 357-366; DOI: https://doi.org/10.1124/jpet.120.000103
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    GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain
    Kathryn Braden, Luigino Antonio Giancotti, Zhoumou Chen, Chelsea DeLeon, Nick Latzo, Terri Boehm, Napoleon D’Cunha, Bonne M. Thompson, Timothy M. Doyle, Jeffrey G. McDonald, John K. Walker, Grant R. Kolar, Christopher Kent Arnatt and Daniela Salvemini
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 367-375; DOI: https://doi.org/10.1124/jpet.120.000105

Metabolism, Transport, and Pharmacogenomics

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    High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid-β Distribution between Brain and Plasma
    Suresh K. Swaminathan, Andrew L. Zhou, Kristen M. Ahlschwede, Geoffry L. Curran, Val J. Lowe, Ling Li and Karunya K. Kandimalla
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 308-316; DOI: https://doi.org/10.1124/jpet.120.265876
  • Ezetimibe Enhances Macrophage-to-Feces Reverse Cholesterol Transport in Golden Syrian Hamsters Fed a High-Cholesterol Diet
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    Ezetimibe Enhances Macrophage-to-Feces Reverse Cholesterol Transport in Golden Syrian Hamsters Fed a High-Cholesterol Diet
    Fatima Kasbi-Chadli, Morgan Treguier, François Briand, Thierry Sulpice and Khadija Ouguerram
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 349-356; DOI: https://doi.org/10.1124/jpet.120.000062
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    Physiologically Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats
    Xiaonan Li, Debra C. DuBois, Richard R. Almon and William J. Jusko
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 385-396; DOI: https://doi.org/10.1124/jpet.120.000191

Neuropharmacology

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    A Novel Potent and Selective Histamine H3 Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, and Wake-Promoting and Procognitive Effects in Rodents
    Noriko Hino, Toshiyuki Marumo, Makiko Kotani, Toshiharu Shimazaki, Ayaka Kaku-Fukumoto, Hirohiko Hikichi, Jun-ichi Karasawa, Yasumitsu Tomishima, Hiroko Komiyama, Emi Tatsuda, Dai Nozawa, Toshio Nakamura and Shigeyuki Chaki
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 276-285; DOI: https://doi.org/10.1124/jpet.120.000185
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    Association Between N-Desmethylclozapine and Clozapine-Induced Sialorrhea: Involvement of Increased Nocturnal Salivary Secretion via Muscarinic Receptors by N-Desmethylclozapine
    Shuhei Ishikawa, Masaki Kobayashi, Naoki Hashimoto, Hideaki Mikami, Akihiko Tanimura, Katsuya Narumi, Ayako Furugen, Ichiro Kusumi and Ken Iseki
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 376-384; DOI: https://doi.org/10.1124/jpet.120.000164

Toxicology

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    Untargeted Metabolomics Reveals Anaerobic Glycolysis as a Novel Target of the Hepatotoxic Antidepressant Nefazodone
    Evelin Krajnc, Michele Visentin, Zhibo Gai, Bruno Stieger, Sophia L. Samodelov, Stephanie Häusler and Gerd A. Kullak-Ublick
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 239-246; DOI: https://doi.org/10.1124/jpet.120.000120

Notice of Retraction

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    Notice of Retraction: Harada S, Yamazaki Y, and Tokuyama S (2013) Orexin-A Suppresses Postischemic Glucose Intolerance and Neuronal Damage through Hypothalamic Brain-Derived Neurotrophic Factor, J Pharmacol Exp Ther, 344: 276-285; DOI: https://doi.org/10.1124/jpet.112.199604
    Journal of Pharmacology and Experimental Therapeutics November 2020, 375 (2) 397; DOI: https://doi.org/10.1124/jpet.112.199604retraction
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 375 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 375, Issue 2
1 Nov 2020
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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Jump to

  • Minireview
  • Behavioral Pharmacology
  • Cardiovascular
  • Drug Discovery and Translational Medicine
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
  • Toxicology
  • Notice of Retraction
  • Most Cited
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.
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