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Research ArticleNeuropharmacology

Duloxetine Attenuates Paclitaxel-Induced Peripheral Nerve Injury by Inhibiting p53-Related Pathways

Yuting Lu, Peng Zhang, Qiuyan Zhang, Chao Yang, Yangyan Qian, Jinshuai Suo, Xinxia Tao and Jing Zhu
Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 453-462; DOI: https://doi.org/10.1124/jpet.120.265082
Yuting Lu
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Peng Zhang
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Qiuyan Zhang
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Chao Yang
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Yangyan Qian
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Jinshuai Suo
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Xinxia Tao
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Jing Zhu
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
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Article Information

vol. 373 no. 3 453-462
DOI 
https://doi.org/10.1124/jpet.120.265082
PubMed 
32238452

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received January 9, 2020
  • Accepted March 18, 2020
  • Published online May 18, 2020.

Article Versions

  • Earlier version (April 1, 2020 - 13:16).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2020 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yuting Lu1,
  2. Peng Zhang1,
  3. Qiuyan Zhang,
  4. Chao Yang,
  5. Yangyan Qian,
  6. Jinshuai Suo,
  7. Xinxia Tao, and
  8. Jing Zhu
  1. Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China (Y.L., P.Z., Q.Z., C.Y., Y.Q., J.S., X.T., J.Z.); Departments of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland (J.Z.)
  1. Address correspondence to:
    Jing Zhu, Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. E-mail: 830640{at}njucm.edu.cn
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Journal of Pharmacology and Experimental Therapeutics: 373 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 373, Issue 3
1 Jun 2020
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Research ArticleNeuropharmacology

Duloxetine Improves PIPN by Inhibiting p53-Related Pathways

Yuting Lu, Peng Zhang, Qiuyan Zhang, Chao Yang, Yangyan Qian, Jinshuai Suo, Xinxia Tao and Jing Zhu
Journal of Pharmacology and Experimental Therapeutics June 1, 2020, 373 (3) 453-462; DOI: https://doi.org/10.1124/jpet.120.265082

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Research ArticleNeuropharmacology

Duloxetine Improves PIPN by Inhibiting p53-Related Pathways

Yuting Lu, Peng Zhang, Qiuyan Zhang, Chao Yang, Yangyan Qian, Jinshuai Suo, Xinxia Tao and Jing Zhu
Journal of Pharmacology and Experimental Therapeutics June 1, 2020, 373 (3) 453-462; DOI: https://doi.org/10.1124/jpet.120.265082
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