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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

June 01, 2020; Volume 373,Issue 3

Minireviews

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    Cytokines and Growth Factors as Predictors of Response to Medical Treatment in Diabetic Macular Edema
    Sónia Torres-Costa, Maria Carolina Alves Valente, Fernando Falcão-Reis and Manuel Falcão
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 445-452; DOI: https://doi.org/10.1124/jpet.119.262956

Behavioral Pharmacology

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    Antinociceptive and Immune Effects of Delta-9-Tetrahydrocannabinol or Cannabidiol in Male Versus Female Rats with Persistent Inflammatory Pain
    Stevie C. Britch, Alan G. Goodman, Jenny L. Wiley, Abby M. Pondelick and Rebecca M. Craft
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 416-428; DOI: https://doi.org/10.1124/jpet.119.263319

Cardiovascular

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    Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase IIβ Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
    Petra Kollárová-Brázdová, Anna Jirkovská, Galina Karabanovich, Zuzana Pokorná, Hana Bavlovič Piskáčková, Eduard Jirkovský, Jan Kubeš, Olga Lenčová-Popelová, Yvona Mazurová, Michaela Adamcová, Veronika Skalická, Petra Štěrbová-Kovaříková, Jaroslav Roh, Tomáš Šimůnek and Martin Štěrba
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 402-415; DOI: https://doi.org/10.1124/jpet.119.264580
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    Adrenoceptor Responses in Human Embryonic Stem Cell–Derived Cardiomyocytes: a Special Focus on Electrophysiological Property
    Weiwei Jiang, Xingjian Hu, Fei Li, Geng Li and Yin Wang
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 429-437; DOI: https://doi.org/10.1124/jpet.120.265686
  • eNOS-Nitric Oxide System Contributes to a Novel Antiatherogenic Effect of Leonurine via Inflammation Inhibition and Plaque Stabilization
    You have access
    eNOS-Nitric Oxide System Contributes to a Novel Antiatherogenic Effect of Leonurine via Inflammation Inhibition and Plaque Stabilization
    Ke Ning, Ming-Jie Wang, Ge Lin, Yi-Lin Zhang, Meng-Yao Li, Bao-Feng Yang, Ying Chen, Yong Huang, Zhi-Ming Li, Yi-Jun Huang, Lei Zhu, Kun Liang, Bo Yu, Yi-Zhun Zhu and Yi-Chun Zhu
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 463-475; DOI: https://doi.org/10.1124/jpet.119.264887

Cellular and Molecular

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    Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine
    Rían W. Manville and Geoffrey W. Abbott
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 391-401; DOI: https://doi.org/10.1124/jpet.119.264507

Drug Discovery and Translational Medicine

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    Pharmacokinetic-Pharmacodynamic-Efficacy Modeling of ONO-7579, a Novel Pan–Tropomyosin Receptor Kinase Inhibitor, in a Murine Xenograft Tumor Model
    Hiroyuki Iida, Ryu Fujikawa, Ryohei Kozaki, Ryuichi Harada, Yuya Hosokawa, Ken-ichi Ogawara and Tomoya Ohno
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 361-369; DOI: https://doi.org/10.1124/jpet.119.264499
  • Distribution and Function of Prostaglandin E<sub>2</sub> Receptors in Mouse Uterus: Translational Value for Human Reproduction
    Open Access
    Distribution and Function of Prostaglandin E2 Receptors in Mouse Uterus: Translational Value for Human Reproduction
    Deborah P. Fischer, Anna L. Griffiths, Sylvia Lui, Uzmah J. Sabar, Diane Farrar, Peter J. O’Donovan, David F. Woodward and Kay M. Marshall
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 381-390; DOI: https://doi.org/10.1124/jpet.119.263509

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Site-Specific and Temporal Effects of Apraglutide, a Novel Long-Acting Glucagon-Like Peptide-2 Receptor Agonist, on Intestinal Growth in Mice
    S.E. Martchenko, M.E. Sweeney, V. Dimitriadou, J.A. Murray and P.L. Brubaker
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 347-352; DOI: https://doi.org/10.1124/jpet.119.263947
  • Open Access
    Pharmacological Profile of Naldemedine, a Peripherally Acting μ-Opioid Receptor Antagonist: Comparison with Naloxone and Naloxegol
    Toshiyuki Kanemasa, Katsumi Koike, Kenji Takase, Tohko Arai, Atsushi Nakamura, Yasuhide Morioka and Minoru Hasegawa
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 438-444; DOI: https://doi.org/10.1124/jpet.119.264515

Inflammation, Immunopharmacology, and Asthma

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    Treatment of Allergic Asthma with Fenretinide Formulation (LAU-7b) Downregulates ORMDL Sphingolipid Biosynthesis Regulator 3 (Ormdl3) Expression and Normalizes Ceramide Imbalance
    Mina Youssef, Juan B. De Sanctis, Juhi Shah, Daciana Catalina Dumut, Marian Hajduch, Anna K. Naumova and Danuta Radzioch
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 476-487; DOI: https://doi.org/10.1124/jpet.119.263715

Metabolism, Transport, and Pharmacogenomics

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    Mechanistic PBPK Modeling of Urine pH Effect on Renal and Systemic Disposition of Methamphetamine and Amphetamine
    Weize Huang, Lindsay C. Czuba and Nina Isoherranen
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 488-501; DOI: https://doi.org/10.1124/jpet.120.264994

Neuropharmacology

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    Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC
    Tomoteru Yamasaki, Tomoyuki Ohya, Wakana Mori, Yiding Zhang, Hidekatsu Wakizaka, Nobuki Nengaki, Masayuki Fujinaga, Tatsuya Kikuchi and Ming-Rong Zhang
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 353-360; DOI: https://doi.org/10.1124/jpet.119.263772
  • Duloxetine Attenuates Paclitaxel-Induced Peripheral Nerve Injury by Inhibiting p53-Related Pathways
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    Duloxetine Attenuates Paclitaxel-Induced Peripheral Nerve Injury by Inhibiting p53-Related Pathways
    Yuting Lu, Peng Zhang, Qiuyan Zhang, Chao Yang, Yangyan Qian, Jinshuai Suo, Xinxia Tao and Jing Zhu
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 453-462; DOI: https://doi.org/10.1124/jpet.120.265082

Toxicology

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    Chronic Ethanol Feeding in Mice Decreases Expression of Genes for Major Structural Bone Proteins in a Nox4-Independent Manner
    Kim B. Pedersen, Michelle L. Osborn, Alex C. Robertson, Ashlee E. Williams, James Watt, Alexandra Denys, Katrin Schröder and Martin J. Ronis
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 337-346; DOI: https://doi.org/10.1124/jpet.119.264374
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    Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor
    Wenqi Cui, Xunan Shen, Emre Agbas, Brandon Tompkins, Hadley Cameron-Carter and Jeff L. Staudinger
    Journal of Pharmacology and Experimental Therapeutics June 2020, 373 (3) 370-380; DOI: https://doi.org/10.1124/jpet.119.264762
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Journal of Pharmacology and Experimental Therapeutics: 373 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 373, Issue 3
1 Jun 2020
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