Journal of Pharmacology and Experimental Therapeutics: 372 (3)

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About the cover: Summary of approaches to obtain human tissue for the support of drug-metabolizing enzyme and transporter profiling. See the article by Rodrigues and Rowland (dx.doi.org/10.1124/jpet.119.262972).

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Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

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