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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

January 01, 2020; Volume 372,Issue 1

Commentary

  • You have access
    New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology
    Martin C. Michel, T.J. Murphy and Harvey J. Motulsky
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 136-147; DOI: https://doi.org/10.1124/jpet.119.264143

Minireviews

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    A Compendium of the Biological Effects of Apolipoprotein A-IMilano
    Cinzia Parolini
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 54-62; DOI: https://doi.org/10.1124/jpet.119.261719

Behavioral Pharmacology

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    The Novel CYP2A6 Inhibitor, DLCI-1, Decreases Nicotine Self-Administration in Mice
    Yen-Chu Chen, James P. Fowler, Jing Wang, Christy J. W. Watson, Yasmine Sherafat, Andres Staben, Philip Lazarus, Travis T. Denton and Christie D. Fowler
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 21-29; DOI: https://doi.org/10.1124/jpet.119.260653
  • Open Access
    The Neuropeptide Y Y2 Receptor Is Coexpressed with Nppb in Primary Afferent Neurons and Y2 Activation Reduces Histaminergic and IL-31-Induced Itch
    Haisha Ma, Tianle Gao, Jon E.T. Jakobsson, Hannah M. Weman, Bo Xu, Dan Larhammar and Malin C. Lagerström
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 73-82; DOI: https://doi.org/10.1124/jpet.119.262584
  • You have access
    Cannabinoid Antagonist Drug Discrimination in Nonhuman Primates
    Brian D. Kangas, Ani S. Zakarian, Kiran Vemuri, Shakiru O. Alapafuja, Shan Jiang, Spyros P. Nikas, Alexandros Makriyannis and Jack Bergman
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 119-127; DOI: https://doi.org/10.1124/jpet.119.261818
  • You have access
    Inhibiting MicroRNA-29a Protects Myocardial Ischemia-Reperfusion Injury by Targeting SIRT1 and Suppressing Oxidative Stress and NLRP3-Mediated Pyroptosis Pathway
    Shoukun Ding, Donghai Liu, Lixia Wang, Guanggong Wang and Yaobin Zhu
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 128-135; DOI: https://doi.org/10.1124/jpet.119.256982

Cardiovascular

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    Complex Effects of Putative DRP-1 Inhibitors on Stress Responses in Mouse Heart and Rat Cardiomyoblasts
    Lauren Wendt, Jelena Vider, Louise E. See Hoe, Eugene Du Toit, Jason N. Peart and John P. Headrick
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 95-106; DOI: https://doi.org/10.1124/jpet.119.258897

Drug Discovery and Translational Medicine

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    The Positive Allosteric Modulator of α2/3-Containing GABAA Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury
    Jeffrey M. Witkin, Guanguan Li, Lalit K. Golani, Wenhui Xiong, Jodi L. Smith, Xingjie Ping, Farjana Rashid, Rajwana Jahan, Rok Cerne, James M. Cook and Xiaoming Jin
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 83-94; DOI: https://doi.org/10.1124/jpet.119.260968
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    Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222
    Ashvani K. Singh, Yihong Fan, Corina Balut, Sara Alani, Arlene M. Manelli, Andrew M. Swensen, Ying Jia, Torben R. Neelands, Timothy A. Vortherms, Bo Liu, Xenia B. Searle, Xueqing Wang, Wenqing Gao, Tzyh-Chang Hwang, Hong Y. Ren, Douglas Cyr, Philip R. Kym, Katja Conrath and Chris Tse
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 107-118; DOI: https://doi.org/10.1124/jpet.119.261800

Gastrointestinal, Hepatic, Pulmonary, and Renal

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    Activation of Prejunctional P2x2/3 Heterotrimers by ATP Enhances the Cholinergic Tone in Obstructed Human Urinary Bladders
    M. Silva-Ramos, I. Silva, M. Faria, F. Ferreirinha and P. Correia-de-Sá
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 63-72; DOI: https://doi.org/10.1124/jpet.119.261610

Metabolism, Transport, and Pharmacogenomics

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    Sampling Site Has a Critical Impact on Physiologically Based Pharmacokinetic Modeling
    Weize Huang and Nina Isoherranen
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 30-45; DOI: https://doi.org/10.1124/jpet.119.262154
  • You have access
    Plasma Membrane Cholesterol Regulates the Allosteric Binding of 1-Methyl-4-Phenylpyridinium to Organic Cation Transporter 2 (SLC22A2)
    Severin Hörmann, Zhibo Gai, Gerd A. Kullak-Ublick and Michele Visentin
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 46-53; DOI: https://doi.org/10.1124/jpet.119.260877

Neuropharmacology

  • Open Access
    Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Interactions with Synaptic Vesicle 2 Proteins and the GABAA Receptor
    Martyn Wood, Veronique Daniels, Laurent Provins, Christian Wolff, Rafal M. Kaminski and Michel Gillard
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 1-10; DOI: https://doi.org/10.1124/jpet.119.261149
  • Open Access
    Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Characterization in Rodent Seizure and Epilepsy Models
    Karine Leclercq, Alain Matagne, Laurent Provins, Henrik Klitgaard and Rafal M. Kaminski
    Journal of Pharmacology and Experimental Therapeutics January 2020, 372 (1) 11-20; DOI: https://doi.org/10.1124/jpet.119.261222
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 372 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 372, Issue 1
1 Jan 2020
  • Table of Contents
  • Table of Contents (PDF)
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  • Commentary
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  • Behavioral Pharmacology
  • Cardiovascular
  • Drug Discovery and Translational Medicine
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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