Research ArticleDrug Discovery and Translational Medicine
In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624
Staci L. Haney
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
Yashpal S. Chhonker
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
Michelle L. Varney
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
Geoffrey Talmon
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
Lynette M. Smith
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
Daryl J. Murry
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
Sarah A. Holstein
Department of Internal Medicine (S.L.H., M.L.V., S.A.H.), Clinical Pharmacology Laboratory, Department of Pharmacy Practice (Y.S.C., D.J.M.), Department of Pathology and Microbiology (G.T.), Fred and Pamela Buffett Cancer Center (D.J.M., S.A.H.), and College of Public Health (L.M.S.), University of Nebraska Medical Center, Omaha, Nebraska
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Research ArticleDrug Discovery and Translational Medicine
Pharmacological Properties of Novel Rab Inhibitors
Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
Journal of Pharmacology and Experimental Therapeutics November 1, 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624
Research ArticleDrug Discovery and Translational Medicine
Pharmacological Properties of Novel Rab Inhibitors
Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
Journal of Pharmacology and Experimental Therapeutics November 1, 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624
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