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Index by author

November 01, 2019; Volume 371,Issue 2

A

  1. Adham, Nika

    1. The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
      Mei Huang, Wenqi He, Béla Kiss, Bence Farkas, Nika Adham and Herbert Y. Meltzer
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 517-525; DOI: https://doi.org/10.1124/jpet.119.259879

  2. Ando, Ayumi

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  3. Andrews, Paul S.

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  4. Arman, Tarana

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

  5. Aubé, Jeffrey

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

B

  1. Balakrishna, Deepika

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  2. Banerjee, Urmi

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  3. Bardo, Michael T.

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  4. Barr, Jeffrey L.

    1. Differential Roles of Accumbal GSK3β in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory
      Xiangdang Shi, Jeffrey L. Barr, Eva von Weltin, Cassandra Wolsh and Ellen M. Unterwald
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 339-347; DOI: https://doi.org/10.1124/jpet.119.259283

  5. Bartkowski, Darian

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  6. Beebe, Jenny

    1. CC-115, a Dual Mammalian Target of Rapamycin/DNA-Dependent Protein Kinase Inhibitor in Clinical Trial, Is a Substrate of ATP-Binding Cassette G2, a Risk Factor for CC-115 Resistance
      Jenny Beebe and Jian-Ting Zhang
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 320-326; DOI: https://doi.org/10.1124/jpet.119.258392

  7. Bergeria, Cecilia L.

    1. Non-Opioid Neurotransmitter Systems that Contribute to the Opioid Withdrawal Syndrome: A Review of Preclinical and Human Evidence
      Kelly E. Dunn, Andrew S. Huhn, Cecilia L. Bergeria, Cassandra D. Gipson and Elise M. Weerts
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 422-452; DOI: https://doi.org/10.1124/jpet.119.258004

  8. Bergman, Jack

    1. Behavioral Effects of Opioid Full and Partial Agonists During Chronic Buprenorphine Treatment
      Sarah L. Withey, Roger D. Spealman, Jack Bergman and Carol A. Paronis
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 544-554; DOI: https://doi.org/10.1124/jpet.119.259010

  9. Bilakovics, James

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  10. Bobardt, Michael

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

  11. Bowman, Melodi A.

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  12. Broens, Suzanne

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  13. Bunce, Matthew

    1. Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
      Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R. Lacy and Madhu Chintala
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 375-384; DOI: https://doi.org/10.1124/jpet.119.261032

C

  1. Cai, Zhulan

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

  2. Carpéné, Christian

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  3. Chaplin, Alice

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  4. Chatterji, Udayan

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

  5. Chen, Hao

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  6. Chen, Hong

    1. Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord
      Shao-Rui Chen, Jixiang Zhang, Hong Chen and Hui-Lin Pan
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 242-249; DOI: https://doi.org/10.1124/jpet.119.261339

  7. Chen, Shao-Rui

    1. Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord
      Shao-Rui Chen, Jixiang Zhang, Hong Chen and Hui-Lin Pan
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 242-249; DOI: https://doi.org/10.1124/jpet.119.261339

  8. Chern, Yijuang

    1. Novel Adenosine Analog, N6-(4-Hydroxybenzyl)-Adenosine, Dampens Alcohol Drinking and Seeking Behaviors
      Sa-Ik Hong, Lee Peyton, Yijuang Chern and Doo-Sup Choi
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 260-267; DOI: https://doi.org/10.1124/jpet.119.261529

  9. Cheruvallath, Zacharia S.

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  10. Chhonker, Yashpal S.

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

  11. Chintala, Madhu

    1. Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
      Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R. Lacy and Madhu Chintala
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 375-384; DOI: https://doi.org/10.1124/jpet.119.261032

  12. Choi, Doo-Sup

    1. Novel Adenosine Analog, N6-(4-Hydroxybenzyl)-Adenosine, Dampens Alcohol Drinking and Seeking Behaviors
      Sa-Ik Hong, Lee Peyton, Yijuang Chern and Doo-Sup Choi
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 260-267; DOI: https://doi.org/10.1124/jpet.119.261529

  13. Clarke, John D.

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

  14. Cote, Thomas E.

    1. Addressing the Opioid Crisis: Medical Student Instruction in Opioid Drug Pharmacology, Pain Management, and Substance Use Disorders
      Brian M. Cox, Thomas E. Cote and Irwin Lucki
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 500-506; DOI: https://doi.org/10.1124/jpet.119.257329

  15. Coussens, Nathan P.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  16. Cox, Brian M.

    1. Addressing the Opioid Crisis: Medical Student Instruction in Opioid Drug Pharmacology, Pain Management, and Substance Use Disorders
      Brian M. Cox, Thomas E. Cote and Irwin Lucki
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 500-506; DOI: https://doi.org/10.1124/jpet.119.257329

  17. Crooks, Peter A.

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  18. Crystal, Roger

    1. Fighting Fire with Fire: Development of Intranasal Nalmefene to Treat Synthetic Opioid Overdose
      Philip Krieter, Shwe Gyaw, Roger Crystal and Phil Skolnick
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 409-415; DOI: https://doi.org/10.1124/jpet.118.256115

  19. Cui, Su-Ying

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  20. Cunningham, Kathryn A.

    1. Translating Pharmacology into Therapeutics to Fight the Opioid Crisis
      Gerard J. Marek, Kathryn A. Cunningham and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 394-395; DOI: https://doi.org/10.1124/jpet.119.262477

D

  1. Dahan, Albert

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  2. Daws, Lynette C.

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  3. Decaunes, Pauline

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  4. Dias, Henrique B.

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  5. Disney, Alex

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  6. Drewes, Asbjørn M.

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  7. Du, Fuyong

    1. Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
      Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R. Lacy and Madhu Chintala
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 375-384; DOI: https://doi.org/10.1124/jpet.119.261032

  8. Duan, MingXia

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

  9. Dunn, Kelly E.

    1. Non-Opioid Neurotransmitter Systems that Contribute to the Opioid Withdrawal Syndrome: A Review of Preclinical and Human Evidence
      Kelly E. Dunn, Andrew S. Huhn, Cecilia L. Bergeria, Cassandra D. Gipson and Elise M. Weerts
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 422-452; DOI: https://doi.org/10.1124/jpet.119.258004

  10. Dwoskin, Linda P.

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

E

  1. Ermolieff, Jacques

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

F

  1. Fanjul, Andrea

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  2. Farkas, Bence

    1. The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
      Mei Huang, Wenqi He, Béla Kiss, Bence Farkas, Nika Adham and Herbert Y. Meltzer
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 517-525; DOI: https://doi.org/10.1124/jpet.119.259879

  3. Farrell, Pamela J.

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  4. Felder, Christian C.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  5. Ferreira, Livia

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  6. Fletcher, Terry W.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  7. Foster, Robert T.

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

  8. France, Charles P.

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  9. Fujimoto, Takuya

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

G

  1. Galanzha, Ekaterina I.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  2. Gallay, Philippe

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

  3. George, Christina M.

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  4. Gerak, Lisa R.

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  5. Ghodrati, Saba

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  6. Gilman, T. Lee

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  7. Gipson, Cassandra D.

    1. Non-Opioid Neurotransmitter Systems that Contribute to the Opioid Withdrawal Syndrome: A Review of Preclinical and Human Evidence
      Kelly E. Dunn, Andrew S. Huhn, Cecilia L. Bergeria, Cassandra D. Gipson and Elise M. Weerts
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 422-452; DOI: https://doi.org/10.1124/jpet.119.258004

  8. Gómez-Zorita, Saioa

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  9. Gonzalez, Frank J.

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  10. Gorby, Heather E.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  11. Gould, Georgianna G.

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  12. Gross, Joshua D.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  13. Gurney, Mark E.

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  14. Gyaw, Shwe

    1. Fighting Fire with Fire: Development of Intranasal Nalmefene to Treat Synthetic Opioid Overdose
      Philip Krieter, Shwe Gyaw, Roger Crystal and Phil Skolnick
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 409-415; DOI: https://doi.org/10.1124/jpet.118.256115

H

  1. Hagenbuch, Bruno

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

  2. Hall, Matthew D.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  3. Haney, Staci L.

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

  4. Harland, Aubrie A.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  5. He, Wenqi

    1. The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
      Mei Huang, Wenqi He, Béla Kiss, Bence Farkas, Nika Adham and Herbert Y. Meltzer
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 517-525; DOI: https://doi.org/10.1124/jpet.119.259879

  6. Holstein, Sarah A.

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

  7. Holub, Corine

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  8. Hong, Sa-Ik

    1. Novel Adenosine Analog, N6-(4-Hydroxybenzyl)-Adenosine, Dampens Alcohol Drinking and Seeking Behaviors
      Sa-Ik Hong, Lee Peyton, Yijuang Chern and Doo-Sup Choi
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 260-267; DOI: https://doi.org/10.1124/jpet.119.261529

  9. Hu, Tongtong

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

  10. Huang, Huey-Jing

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  11. Huang, Mei

    1. The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
      Mei Huang, Wenqi He, Béla Kiss, Bence Farkas, Nika Adham and Herbert Y. Meltzer
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 517-525; DOI: https://doi.org/10.1124/jpet.119.259879

  12. Huang Devine, Zheng

    1. Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
      Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R. Lacy and Madhu Chintala
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 375-384; DOI: https://doi.org/10.1124/jpet.119.261032

  13. Huhn, Andrew S.

    1. Non-Opioid Neurotransmitter Systems that Contribute to the Opioid Withdrawal Syndrome: A Review of Preclinical and Human Evidence
      Kelly E. Dunn, Andrew S. Huhn, Cecilia L. Bergeria, Cassandra D. Gipson and Elise M. Weerts
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 422-452; DOI: https://doi.org/10.1124/jpet.119.258004

  14. Husbands, Stephen M.

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

I

  1. Ikeda, Shota

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  2. Itokawa, Shigekazu

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

J

  1. Janganati, Venumadhav

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  2. Janowsky, Aaron

    1. Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis
      Randy Torralva and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 453-475; DOI: https://doi.org/10.1124/jpet.119.258566

  3. Jonson, Samantha G.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

K

  1. Kaski, Shane W.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  2. Kenakin, Terry

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  3. Kim, Donghwan

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  4. Kimura, Shioko

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  5. Kinsey, Steven G.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  6. Kiss, Béla

    1. The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
      Mei Huang, Wenqi He, Béla Kiss, Bence Farkas, Nika Adham and Herbert Y. Meltzer
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 517-525; DOI: https://doi.org/10.1124/jpet.119.259879

  7. Klimberg, V. Suzanne

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  8. Knutson, Charles G.

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  9. Kornecook, Thomas

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  10. Krausz, Kristopher W.

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  11. Krieter, Philip

    1. Fighting Fire with Fire: Development of Intranasal Nalmefene to Treat Synthetic Opioid Overdose
      Philip Krieter, Shwe Gyaw, Roger Crystal and Phil Skolnick
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 409-415; DOI: https://doi.org/10.1124/jpet.118.256115

  12. Kubo, Kazuki

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  13. Kuo, Joseph

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

L

  1. Lacy, Eilyn R.

    1. Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
      Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R. Lacy and Madhu Chintala
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 375-384; DOI: https://doi.org/10.1124/jpet.119.261032

  2. Larson, Christopher J.

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  3. Latham, Elizabeth

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  4. Lee, Na-Ra

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  5. Leggas, Markos

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  6. Le Gonidec, Sophie

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  7. Li, Qiu

    1. Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
      Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R. Lacy and Madhu Chintala
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 375-384; DOI: https://doi.org/10.1124/jpet.119.261032

  8. Lillis, Katherine V.

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  9. Liu, Chen

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

  10. Lucki, Irwin

    1. Addressing the Opioid Crisis: Medical Student Instruction in Opioid Drug Pharmacology, Pain Management, and Substance Use Disorders
      Brian M. Cox, Thomas E. Cote and Irwin Lucki
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 500-506; DOI: https://doi.org/10.1124/jpet.119.257329

  11. Lynch, Katherine D.

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

M

  1. Marecki, John C.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  2. Marek, Gerard J.

    1. Translating Pharmacology into Therapeutics to Fight the Opioid Crisis
      Gerard J. Marek, Kathryn A. Cunningham and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 394-395; DOI: https://doi.org/10.1124/jpet.119.262477

  3. Matuszkiewicz, Jennifer

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  4. Mayo, Patrick R.

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

  5. Mazur, Crystal

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  6. McBride, Christopher

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  7. McCarty, William J.

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  8. McManus, Owen B.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  9. Meltzer, Herbert Y.

    1. The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens
      Mei Huang, Wenqi He, Béla Kiss, Bence Farkas, Nika Adham and Herbert Y. Meltzer
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 517-525; DOI: https://doi.org/10.1124/jpet.119.259879

  10. Mercader, Josep

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  11. Metzel, Lauren

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  12. Meyer, James T.

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  13. Milagro, Fermín I.

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  14. Minervini, Vanessa

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  15. Montonye, Michelle L.

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

  16. Murry, Daryl J.

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

N

  1. Nickell, Justin R.

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  2. Niesters, Marieke

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

O

  1. O’Donnell, James M.

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  2. Olesen, Anne E.

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  3. Olesen, Søren S.

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  4. Olofsen, Erik

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  5. Owens, W. Anthony

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

P

  1. Pachori, Alok

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  2. Paine, Mary F.

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

  3. Pan, Hui-Lin

    1. Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord
      Shao-Rui Chen, Jixiang Zhang, Hong Chen and Hui-Lin Pan
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 242-249; DOI: https://doi.org/10.1124/jpet.119.261339

  4. Paronis, Carol A.

    1. Behavioral Effects of Opioid Full and Partial Agonists During Chronic Buprenorphine Treatment
      Sarah L. Withey, Roger D. Spealman, Jack Bergman and Carol A. Paronis
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 544-554; DOI: https://doi.org/10.1124/jpet.119.259010

  5. Patel, Daxesh P.

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  6. Peyton, Lee

    1. Novel Adenosine Analog, N6-(4-Hydroxybenzyl)-Adenosine, Dampens Alcohol Drinking and Seeking Behaviors
      Sa-Ik Hong, Lee Peyton, Yijuang Chern and Doo-Sup Choi
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 260-267; DOI: https://doi.org/10.1124/jpet.119.261529

  7. Plonowski, Artur

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  8. Prisinzano, Thomas E.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  9. Pulaski, Lukasz

    1. Direct Measurement of Kinetic Parameters of ABCG2-Dependent Transport of Natural Flavonoids Using a Fluorogenic Substrate
      Michal Rozanski, Maciej Studzian and Lukasz Pulaski
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 309-319; DOI: https://doi.org/10.1124/jpet.119.261347

R

  1. Rasmussen, Kurt

    1. Translating Pharmacology into Therapeutics to Fight the Opioid Crisis
      Gerard J. Marek, Kathryn A. Cunningham and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 394-395; DOI: https://doi.org/10.1124/jpet.119.262477
    2. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  2. Rhee, Sung W.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  3. Roberts, Jonathan

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  4. Rolzin, Paul

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028

  5. Rozanski, Michal

    1. Direct Measurement of Kinetic Parameters of ABCG2-Dependent Transport of Natural Flavonoids Using a Fluorogenic Substrate
      Michal Rozanski, Maciej Studzian and Lukasz Pulaski
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 309-319; DOI: https://doi.org/10.1124/jpet.119.261347

  6. Rusch, Nancy J.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

S

  1. Sabater, Agustín G.

    1. Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet
      Josep Mercader, Agustín G. Sabater, Sophie Le Gonidec, Pauline Decaunes, Alice Chaplin, Saioa Gómez-Zorita, Fermín I. Milagro and Christian Carpéné
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 555-566; DOI: https://doi.org/10.1124/jpet.119.259895

  2. Sarimollaoglu, Mustafa

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  3. Satomi, Yoshinori

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  4. Schneider, Stephen

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  5. Setola, Vincent

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  6. Shi, Xiangdang

    1. Differential Roles of Accumbal GSK3β in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory
      Xiangdang Shi, Jeffrey L. Barr, Eva von Weltin, Cassandra Wolsh and Ellen M. Unterwald
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 339-347; DOI: https://doi.org/10.1124/jpet.119.259283

  7. Shinohara, Hiromi

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  8. Siderovski, David P.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  9. Sittampalam, G. Sitta

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  10. Skolnick, Phil

    1. Fighting Fire with Fire: Development of Intranasal Nalmefene to Treat Synthetic Opioid Overdose
      Philip Krieter, Shwe Gyaw, Roger Crystal and Phil Skolnick
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 409-415; DOI: https://doi.org/10.1124/jpet.118.256115

  11. Smith, Lynette M.

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

  12. Soto, Marcus

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  13. Sparling, Brian A.

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  14. Spealman, Roger D.

    1. Behavioral Effects of Opioid Full and Partial Agonists During Chronic Buprenorphine Treatment
      Sarah L. Withey, Roger D. Spealman, Jack Bergman and Carol A. Paronis
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 544-554; DOI: https://doi.org/10.1124/jpet.119.259010

  15. Stolarz, Amanda J.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  16. Studzian, Maciej

    1. Direct Measurement of Kinetic Parameters of ABCG2-Dependent Transport of Natural Flavonoids Using a Fluorogenic Substrate
      Michal Rozanski, Maciej Studzian and Lukasz Pulaski
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 309-319; DOI: https://doi.org/10.1124/jpet.119.261347

  17. Suzuki, Hideo

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

T

  1. Takagahara, Shuichi

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  2. Talmon, Geoffrey

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

  3. Tamiz, Amir P.

    1. The Opioid Crisis and the Future of Addiction and Pain Therapeutics
      Nathan P. Coussens, G. Sitta Sittampalam, Samantha G. Jonson, Matthew D. Hall, Heather E. Gorby, Amir P. Tamiz, Owen B. McManus, Christian C. Felder and Kurt Rasmussen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 396-408; DOI: https://doi.org/10.1124/jpet.119.259408

  4. Tan, Helming

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  5. Tang, Qizhu

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

  6. Tian, Dan-Dan

    1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
      Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Katherine D. Lynch, Bruno Hagenbuch, Mary F. Paine and John D. Clarke
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 385-393; DOI: https://doi.org/10.1124/jpet.119.260489

  7. Toney, Glenn M.

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  8. Torralva, Randy

    1. Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis
      Randy Torralva and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 453-475; DOI: https://doi.org/10.1124/jpet.119.258566

  9. Trepanier, Daniel J.

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

  10. Trexler, Kristen R.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

U

  1. Unterwald, Ellen M.

    1. Differential Roles of Accumbal GSK3β in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory
      Xiangdang Shi, Jeffrey L. Barr, Eva von Weltin, Cassandra Wolsh and Ellen M. Unterwald
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 339-347; DOI: https://doi.org/10.1124/jpet.119.259283

  2. Ure, Daren R.

    1. Open Access
      A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
      Joseph Kuo, Michael Bobardt, Udayan Chatterji, Patrick R. Mayo, Daniel J. Trepanier, Robert T. Foster, Philippe Gallay and Daren R. Ure
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 231-241; DOI: https://doi.org/10.1124/jpet.119.261099

V

  1. van Velzen, Monique

    1. A Pragmatic Utility Function to Describe the Risk-Benefit Composite of Opioid and Nonopioid Analgesic Medication
      Anne E. Olesen, Suzanne Broens, Søren S. Olesen, Marieke Niesters, Monique van Velzen, Asbjørn M. Drewes, Albert Dahan and Erik Olofsen
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 416-421; DOI: https://doi.org/10.1124/jpet.118.253716

  2. Varney, Michelle L.

    1. In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution
      Staci L. Haney, Yashpal S. Chhonker, Michelle L. Varney, Geoffrey Talmon, Lynette M. Smith, Daryl J. Murry and Sarah A. Holstein
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 327-338; DOI: https://doi.org/10.1124/jpet.119.258624

  3. Vitela, Melissa

    1. Open Access
      Age- and Sex-Specific Plasticity in Dopamine Transporter Function Revealed by Food Restriction and Exercise in a Rat Activity-Based Anorexia Paradigm
      T. Lee Gilman, W. Anthony Owens, Christina M. George, Lauren Metzel, Melissa Vitela, Livia Ferreira, Melodi A. Bowman, Georgianna G. Gould, Glenn M. Toney and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 268-277; DOI: https://doi.org/10.1124/jpet.119.260794

  4. von Weltin, Eva

    1. Differential Roles of Accumbal GSK3β in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory
      Xiangdang Shi, Jeffrey L. Barr, Eva von Weltin, Cassandra Wolsh and Ellen M. Unterwald
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 339-347; DOI: https://doi.org/10.1124/jpet.119.259283

W

  1. Weerts, Elise M.

    1. Non-Opioid Neurotransmitter Systems that Contribute to the Opioid Withdrawal Syndrome: A Review of Preclinical and Human Evidence
      Kelly E. Dunn, Andrew S. Huhn, Cecilia L. Bergeria, Cassandra D. Gipson and Elise M. Weerts
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 422-452; DOI: https://doi.org/10.1124/jpet.119.258004

  2. White, Allison N.

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  3. Withey, Sarah L.

    1. Behavioral Effects of Opioid Full and Partial Agonists During Chronic Buprenorphine Treatment
      Sarah L. Withey, Roger D. Spealman, Jack Bergman and Carol A. Paronis
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 544-554; DOI: https://doi.org/10.1124/jpet.119.259010

  4. Wix, Kim

    1. Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine
      Shane W. Kaski, Allison N. White, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas E. Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David P. Siderovski and Vincent Setola
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 487-499; DOI: https://doi.org/10.1124/jpet.118.255661

  5. Wolsh, Cassandra

    1. Differential Roles of Accumbal GSK3β in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory
      Xiangdang Shi, Jeffrey L. Barr, Eva von Weltin, Cassandra Wolsh and Ellen M. Unterwald
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 339-347; DOI: https://doi.org/10.1124/jpet.119.259283

  6. Wooden, Jessica

    1. Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
      Lisa R. Gerak, Vanessa Minervini, Elizabeth Latham, Saba Ghodrati, Katherine V. Lillis, Jessica Wooden, Alex Disney, Stephen M. Husbands and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 507-516; DOI: https://doi.org/10.1124/jpet.119.260331

  7. Wu, QingQing

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

X

  1. Xie, Qingwen

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

  2. Xu, Ying

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

Y

  1. Yamamoto, Takeshi

    1. A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice
      Shuichi Takagahara, Hiromi Shinohara, Shigekazu Itokawa, Yoshinori Satomi, Ayumi Ando, Takeshi Yamamoto, Hideo Suzuki, Takuya Fujimoto, Kazuki Kubo and Shota Ikeda
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 290-298; DOI: https://doi.org/10.1124/jpet.119.259846

  2. Yan, Tingting

    1. Withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      Daxesh P. Patel, Tingting Yan, Donghwan Kim, Henrique B. Dias, Kristopher W. Krausz, Shioko Kimura and Frank J. Gonzalez
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 360-374; DOI: https://doi.org/10.1124/jpet.119.256792

  3. Yang, Ming-Xin

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  4. Yuan, Yuan

    1. Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice
      MingXia Duan, Yuan Yuan, Chen Liu, Zhulan Cai, Qingwen Xie, Tongtong Hu, Qizhu Tang and QingQing Wu
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 348-359; DOI: https://doi.org/10.1124/jpet.119.259069

Z

  1. Zhang, Han-Ting

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  2. Zhang, Jian-Ting

    1. CC-115, a Dual Mammalian Target of Rapamycin/DNA-Dependent Protein Kinase Inhibitor in Clinical Trial, Is a Substrate of ATP-Binding Cassette G2, a Risk Factor for CC-115 Resistance
      Jenny Beebe and Jian-Ting Zhang
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 320-326; DOI: https://doi.org/10.1124/jpet.119.258392

  3. Zhang, Jixiang

    1. Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord
      Shao-Rui Chen, Jixiang Zhang, Hong Chen and Hui-Lin Pan
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 242-249; DOI: https://doi.org/10.1124/jpet.119.261339

  4. Zhang, Maosheng

    1. Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat
      James T. Meyer, Brian A. Sparling, William J. McCarty, Maosheng Zhang, Marcus Soto, Stephen Schneider, Hao Chen, Jonathan Roberts, Helming Tan, Thomas Kornecook, Paul S. Andrews and Charles G. Knutson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 476-486; DOI: https://doi.org/10.1124/jpet.119.257105

  5. Zhang, Yong-He

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  6. Zharov, Vladimir P.

    1. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow
      Amanda J. Stolarz, Mustafa Sarimollaoglu, John C. Marecki, Terry W. Fletcher, Ekaterina I. Galanzha, Sung W. Rhee, Vladimir P. Zharov, V. Suzanne Klimberg and Nancy J. Rusch
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 278-289; DOI: https://doi.org/10.1124/jpet.119.257592

  7. Zheng, Guangrong

    1. GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine
      Na-Ra Lee, Guangrong Zheng, Markos Leggas, Venumadhav Janganati, Justin R. Nickell, Peter A. Crooks, Michael T. Bardo and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 526-543; DOI: https://doi.org/10.1124/jpet.119.258699

  8. Zheng, Victor

    1. Open Access
      Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
      Su-Ying Cui, Ming-Xin Yang, Yong-He Zhang, Victor Zheng, Han-Ting Zhang, Mark E. Gurney, Ying Xu and James M. O’Donnell
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 250-259; DOI: https://doi.org/10.1124/jpet.119.259986

  9. Zopf, Christopher J.

    1. Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors
      Pamela J. Farrell, Christopher J. Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub, James Bilakovics, Andrea Fanjul, Jennifer Matuszkiewicz, Artur Plonowski, Paul Rolzin, Urmi Banerjee, Jacques Ermolieff, Zacharia S. Cheruvallath, Christopher McBride, Darian Bartkowski, Crystal Mazur, Alok Pachori and Christopher J. Larson
      Journal of Pharmacology and Experimental Therapeutics November 2019, 371 (2) 299-308; DOI: https://doi.org/10.1124/jpet.119.259028
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