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Research ArticleNeuropharmacology

Tetrabenazine Facilitates Exocytosis by Enhancing Calcium-Induced Calcium Release through Ryanodine Receptors

Ricardo de Pascual, Nuria Álvarez-Ortego, Cristóbal de los Ríos, Gema Jacob-Mazariego and Antonio G. García
Journal of Pharmacology and Experimental Therapeutics October 2019, 371 (1) 219-230; DOI: https://doi.org/10.1124/jpet.119.256560
Ricardo de Pascual
Instituto Teófilo Hernando, Madrid, Spain (R.d.P., N.Á.-O., C.d.l.R., G.J.-M., A.G.G.); and Departamento de Farmacología y Terapéutica (R.d.P., N.Á.-O., G.J.-M., A.G.G.) and Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa (C.d.l.R., A.G.G.), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
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Nuria Álvarez-Ortego
Instituto Teófilo Hernando, Madrid, Spain (R.d.P., N.Á.-O., C.d.l.R., G.J.-M., A.G.G.); and Departamento de Farmacología y Terapéutica (R.d.P., N.Á.-O., G.J.-M., A.G.G.) and Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa (C.d.l.R., A.G.G.), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
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Cristóbal de los Ríos
Instituto Teófilo Hernando, Madrid, Spain (R.d.P., N.Á.-O., C.d.l.R., G.J.-M., A.G.G.); and Departamento de Farmacología y Terapéutica (R.d.P., N.Á.-O., G.J.-M., A.G.G.) and Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa (C.d.l.R., A.G.G.), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
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Gema Jacob-Mazariego
Instituto Teófilo Hernando, Madrid, Spain (R.d.P., N.Á.-O., C.d.l.R., G.J.-M., A.G.G.); and Departamento de Farmacología y Terapéutica (R.d.P., N.Á.-O., G.J.-M., A.G.G.) and Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa (C.d.l.R., A.G.G.), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
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Antonio G. García
Instituto Teófilo Hernando, Madrid, Spain (R.d.P., N.Á.-O., C.d.l.R., G.J.-M., A.G.G.); and Departamento de Farmacología y Terapéutica (R.d.P., N.Á.-O., G.J.-M., A.G.G.) and Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa (C.d.l.R., A.G.G.), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
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Article Information

vol. 371 no. 1 219-230
DOI 
https://doi.org/10.1124/jpet.119.256560
PubMed 
31209099

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received March 11, 2019
  • Accepted June 4, 2019
  • Published online September 20, 2019.

Article Versions

  • Earlier version (June 17, 2019 - 13:01).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ricardo de Pascual,
  2. Nuria Álvarez-Ortego,
  3. Cristóbal de los Ríos,
  4. Gema Jacob-Mazariego, and
  5. Antonio G. García
  1. Instituto Teófilo Hernando, Madrid, Spain (R.d.P., N.Á.-O., C.d.l.R., G.J.-M., A.G.G.); and Departamento de Farmacología y Terapéutica (R.d.P., N.Á.-O., G.J.-M., A.G.G.) and Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa (C.d.l.R., A.G.G.), Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
  1. Address correspondence to:
    Antonio G. García, Instituto Teófilo Hernando, Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad Autónoma de Madrid, Arzobispo Morcillo, 4. 28029 Madrid, Spain. E-mail: agg{at}uam.es
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Journal of Pharmacology and Experimental Therapeutics: 371 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 371, Issue 1
1 Oct 2019
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Research ArticleNeuropharmacology

Tetrabenazine Facilitates Exocytosis through Ryanodine Receptor

Ricardo de Pascual, Nuria Álvarez-Ortego, Cristóbal de los Ríos, Gema Jacob-Mazariego and Antonio G. García
Journal of Pharmacology and Experimental Therapeutics October 1, 2019, 371 (1) 219-230; DOI: https://doi.org/10.1124/jpet.119.256560

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Research ArticleNeuropharmacology

Tetrabenazine Facilitates Exocytosis through Ryanodine Receptor

Ricardo de Pascual, Nuria Álvarez-Ortego, Cristóbal de los Ríos, Gema Jacob-Mazariego and Antonio G. García
Journal of Pharmacology and Experimental Therapeutics October 1, 2019, 371 (1) 219-230; DOI: https://doi.org/10.1124/jpet.119.256560
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