Circadian Rhythm Parameters for CST |
T (h) | Biorhythmic period | 24a,b,c |
a0 | Fourier coefficient | 115.7a,b/254.4b |
a1 | −120.9a,b/−168.7b |
a2 | 38.8a,b/56.9b |
b1 | −41.1a,b/−95.6b |
b2 | 1.6a,b/29.1b |
Pharmacodynamic Parameters |
kdeg,CST (h−1) | Loss rate constant for CST | 1.38 (12.6)a,b,c |
τ (h) | Time to CSTstress | 0.34 (12.8)a,b,c |
CSTstress (ng/ml) | Maximal CST due to stress | 535 (18.0)a/1292 (13.3)b/1397 (12.9)c |
IC50,CST (ng/ml) | Half-maximal inhibition concentration | 3.4 (47.6)a/41.6 (48.0)b/12.9 (45.6)c |