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Research ArticleMetabolism, Transport, and Pharmacogenomics

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat

Vivaswath S. Ayyar, Dawei Song, Debra C. DuBois, Richard R. Almon and William J. Jusko
Journal of Pharmacology and Experimental Therapeutics August 2019, 370 (2) 318-326; DOI: https://doi.org/10.1124/jpet.119.257519
Vivaswath S. Ayyar
Departments of Pharmaceutical Sciences (V.S.A., D.S., D.C.D., R.R.A., W.J.J.) and Biological Sciences (D.C.D., R.R.A.), State University of New York at Buffalo, Buffalo, New York
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Dawei Song
Departments of Pharmaceutical Sciences (V.S.A., D.S., D.C.D., R.R.A., W.J.J.) and Biological Sciences (D.C.D., R.R.A.), State University of New York at Buffalo, Buffalo, New York
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Debra C. DuBois
Departments of Pharmaceutical Sciences (V.S.A., D.S., D.C.D., R.R.A., W.J.J.) and Biological Sciences (D.C.D., R.R.A.), State University of New York at Buffalo, Buffalo, New York
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Richard R. Almon
Departments of Pharmaceutical Sciences (V.S.A., D.S., D.C.D., R.R.A., W.J.J.) and Biological Sciences (D.C.D., R.R.A.), State University of New York at Buffalo, Buffalo, New York
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William J. Jusko
Departments of Pharmaceutical Sciences (V.S.A., D.S., D.C.D., R.R.A., W.J.J.) and Biological Sciences (D.C.D., R.R.A.), State University of New York at Buffalo, Buffalo, New York
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Article Information

vol. 370 no. 2 318-326
DOI 
https://doi.org/10.1124/jpet.119.257519
PubMed 
31197020

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 15, 2019
  • Accepted June 10, 2019
  • Published online July 24, 2019.

Article Versions

  • Earlier version (June 13, 2019 - 08:26).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Vivaswath S. Ayyar,
  2. Dawei Song,
  3. Debra C. DuBois,
  4. Richard R. Almon, and
  5. William J. Jusko
  1. Departments of Pharmaceutical Sciences (V.S.A., D.S., D.C.D., R.R.A., W.J.J.) and Biological Sciences (D.C.D., R.R.A.), State University of New York at Buffalo, Buffalo, New York
  1. Address correspondence to:
    Dr. William J. Jusko, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, NY 14214. E-mail: wjjusko{at}buffalo.edu
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Journal of Pharmacology and Experimental Therapeutics: 370 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 370, Issue 2
1 Aug 2019
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Research ArticleMetabolism, Transport, and Pharmacogenomics

Determination and Prediction of Steroid Tissue Binding

Vivaswath S. Ayyar, Dawei Song, Debra C. DuBois, Richard R. Almon and William J. Jusko
Journal of Pharmacology and Experimental Therapeutics August 1, 2019, 370 (2) 318-326; DOI: https://doi.org/10.1124/jpet.119.257519

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Determination and Prediction of Steroid Tissue Binding

Vivaswath S. Ayyar, Dawei Song, Debra C. DuBois, Richard R. Almon and William J. Jusko
Journal of Pharmacology and Experimental Therapeutics August 1, 2019, 370 (2) 318-326; DOI: https://doi.org/10.1124/jpet.119.257519
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