Table of Contents

Drug Discovery and Translational Medicine

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  Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs

  Scott J. Weir, Robyn Wood, Karl Schorno, Amanda E. Brinker, Prabhu Ramamoorthy, Kathy Heppert, Lian Rajewski, Mehmet Tanol, Tammy Ham, Michael J. McKenna, William McCulloch, Michael Dalton, Gregory A. Reed, Roy A. Jensen, Michael J. Baltezor, Shrikant Anant and John A. Taylor

  Journal of Pharmacology and Experimental Therapeutics August 2019, 370 (2) 148-159; DOI: https://doi.org/10.1124/jpet.119.257972
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  A Reduction in B, T, and Natural Killer Cells Expressing CD38 by TAK-079 Inhibits the Induction and Progression of Collagen-Induced Arthritis in Cynomolgus Monkeys

  Wouter Korver, Mary Carsillo, Josh Yuan, Neeraja Idamakanti, Matthew Wagoner, Pu Shi, Cindy Q. Xia, Glennda Smithson, Lachy McLean, Jonathan Zalevsky and Eric R. Fedyk

  Journal of Pharmacology and Experimental Therapeutics August 2019, 370 (2) 182-196; DOI: https://doi.org/10.1124/jpet.119.256602
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  Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy

  Jonathan Oliva, Scott Galasinski, Amelia Richey, Amy E. Campbell, Marvin J. Meyers, Neal Modi, Jun Wen Zhong, Rabi Tawil, Stephen J. Tapscott and Francis M. Sverdrup

  Journal of Pharmacology and Experimental Therapeutics August 2019, 370 (2) 219-230; DOI: https://doi.org/10.1124/jpet.119.259663
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  Blood Pharmacokinetics Imaging by Noninvasive Heart Fluorescence Tomography and Application to Kidney Glomerular Filtration Rate Assessment

  Bagna Bao, Kristine O. Vasquez, Guojie Ho, Jun Zhang, Jeannine Delaney, Milind Rajopadhye and Jeffrey D. Peterson

  Journal of Pharmacology and Experimental Therapeutics August 2019, 370 (2) 288-298; DOI: https://doi.org/10.1124/jpet.119.257071