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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Combining Multiscale Experimental and Computational Systems Pharmacological Approaches to Overcome Resistance to HER2-targeted Therapy in Breast Cancer

Tanaya R. Vaidya, Anusha Ande and Sihem Ait-Oudhia
Journal of Pharmacology and Experimental Therapeutics June 2019, 369 (3) 531-545; DOI: https://doi.org/10.1124/jpet.118.255752
Tanaya R. Vaidya
Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida
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Anusha Ande
Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida
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Sihem Ait-Oudhia
Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida
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Article Information

vol. 369 no. 3 531-545
DOI 
https://doi.org/10.1124/jpet.118.255752
PubMed 
30898866

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received December 10, 2018
  • Accepted March 15, 2019
  • Published online May 17, 2019.

Article Versions

  • Earlier version (March 21, 2019 - 06:40).
  • Earlier version (March 27, 2019 - 10:45).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Tanaya R. Vaidya1,
  2. Anusha Ande1, and
  3. Sihem Ait-Oudhia
  1. Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida
  1. Address correspondence to:
    Dr. Sihem Ait-Oudhia, Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, 6550 Sanger Road, Office #469, Orlando, FL 32827. E-mail: sihem.bihorel{at}cop.ufl.edu
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Journal of Pharmacology and Experimental Therapeutics: 369 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 369, Issue 3
1 Jun 2019
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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Triple Combination Therapy in Resistant HER2+ Breast Cancer

Tanaya R. Vaidya, Anusha Ande and Sihem Ait-Oudhia
Journal of Pharmacology and Experimental Therapeutics June 1, 2019, 369 (3) 531-545; DOI: https://doi.org/10.1124/jpet.118.255752

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Research ArticleChemotherapy, Antibiotics, and Gene Therapy

Triple Combination Therapy in Resistant HER2+ Breast Cancer

Tanaya R. Vaidya, Anusha Ande and Sihem Ait-Oudhia
Journal of Pharmacology and Experimental Therapeutics June 1, 2019, 369 (3) 531-545; DOI: https://doi.org/10.1124/jpet.118.255752
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