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Research ArticleNeuropharmacology
Open Access

Icariin Delays Brain Aging in Senescence-Accelerated Mouse Prone 8 (SAMP8) Model via Inhibiting Autophagy

Fa-Ju Chen, Bo Liu, Qin Wu, Jie Liu, Yun-Yan Xu, Shao-Yu Zhou and Jing-Shan Shi
Journal of Pharmacology and Experimental Therapeutics April 2019, 369 (1) 121-128; DOI: https://doi.org/10.1124/jpet.118.253310
Fa-Ju Chen
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Bo Liu
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Qin Wu
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Jie Liu
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Yun-Yan Xu
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Shao-Yu Zhou
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Jing-Shan Shi
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
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Article Information

vol. 369 no. 1 121-128
DOI 
https://doi.org/10.1124/jpet.118.253310
PubMed 
30837279

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 30, 2018
  • Accepted February 6, 2019
  • Published online March 15, 2019.

Article Versions

  • Earlier version (March 5, 2019 - 07:58).
  • Earlier version (March 7, 2019 - 10:19).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license.

Author Information

  1. Fa-Ju Chen1,
  2. Bo Liu1,
  3. Qin Wu,
  4. Jie Liu,
  5. Yun-Yan Xu,
  6. Shao-Yu Zhou, and
  7. Jing-Shan Shi
  1. Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, People’s Republic of China
  1. Address correspondence to:
    Dr. Jing-Shan Shi, Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi 563000, People’s Republic of China. E-mail: shijingshan2018{at}163.com
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Journal of Pharmacology and Experimental Therapeutics: 369 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 369, Issue 1
1 Apr 2019
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Research ArticleNeuropharmacology

Icariin Delays Brain Aging

Fa-Ju Chen, Bo Liu, Qin Wu, Jie Liu, Yun-Yan Xu, Shao-Yu Zhou and Jing-Shan Shi
Journal of Pharmacology and Experimental Therapeutics April 1, 2019, 369 (1) 121-128; DOI: https://doi.org/10.1124/jpet.118.253310

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Research ArticleNeuropharmacology

Icariin Delays Brain Aging

Fa-Ju Chen, Bo Liu, Qin Wu, Jie Liu, Yun-Yan Xu, Shao-Yu Zhou and Jing-Shan Shi
Journal of Pharmacology and Experimental Therapeutics April 1, 2019, 369 (1) 121-128; DOI: https://doi.org/10.1124/jpet.118.253310
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