Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

March 01, 2019; Volume 368,Issue 3

Cardiovascular

  • Open Access
    Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental Hypertension
    Frederic Trensz, Céline Bortolamiol, Markus Kramberg, Daniel Wanner, Hakim Hadana, Markus Rey, Daniel S. Strasser, Stéphane Delahaye, Patrick Hess, Enrico Vezzali, Ulrich Mentzel, Joël Ménard, Martine Clozel and Marc Iglarz
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 462-473; DOI: https://doi.org/10.1124/jpet.118.253864
  • You have access
    Empagliflozin, an SGLT2 Inhibitor, Reduced the Mortality Rate after Acute Myocardial Infarction with Modification of Cardiac Metabolomes and Antioxidants in Diabetic Rats
    Hiroto Oshima, Takayuki Miki, Atsushi Kuno, Masashi Mizuno, Tatsuya Sato, Masaya Tanno, Toshiyuki Yano, Kei Nakata, Yukishige Kimura, Koki Abe, Wataru Ohwada and Tetsuji Miura
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 524-534; DOI: https://doi.org/10.1124/jpet.118.253666

Cellular and Molecular

  • You have access
    Synthetic Cannabinoid Hydroxypentyl Metabolites Retain Efficacy at Human Cannabinoid Receptors
    Thomas F. Gamage, Charlotte E. Farquhar, Ryan J. McKinnie, Richard C. Kevin, Iain S. McGregor, Mark L. Trudell, Jenny L. Wiley and Brian F. Thomas
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 414-422; DOI: https://doi.org/10.1124/jpet.118.254425
  • You have access
    Endothelial Cell–Targeted Deletion of PPARγ Blocks Rosiglitazone-Induced Plasma Volume Expansion and Vascular Remodeling in Adipose Tissue
    Taro E. Akiyama, Graham E. Skelhorne-Gross, Elizabeth D. Lightbody, Rachel E. Rubino, Jia Yue Shi, Lesley A. McNamara, Neelam Sharma, Emanuel I. Zycband, Frank J. Gonzalez, Haiying Liu, John W. Woods, C. H. Chang, Joel P. Berger and Christopher J. B. Nicol
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 514-523; DOI: https://doi.org/10.1124/jpet.118.250985

Drug Discovery and Translational Medicine

  • You have access
    Inhibition of COX-2 and EGFR by Melafolone Improves Anti-PD-1 Therapy through Vascular Normalization and PD-L1 Downregulation in Lung Cancer
    Honglin Tang, Yanzhuo Liu, Chenlong Wang, Hao Zheng, Yaxin Chen, Wen Liu, Xuewei Chen, Jing Zhang, Honglei Chen, Yuqing Yang and Jing Yang
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 401-413; DOI: https://doi.org/10.1124/jpet.118.254359
  • You have access
    LCAT Enzyme Replacement Therapy Reduces LpX and Improves Kidney Function in a Mouse Model of Familial LCAT Deficiency
    Boris L. Vaisman, Edward B. Neufeld, Lita A. Freeman, Scott M. Gordon, Maureen L. Sampson, Milton Pryor, Emily Hillman, Milton J. Axley, Sotirios K. Karathanasis and Alan T. Remaley
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 423-434; DOI: https://doi.org/10.1124/jpet.118.251876
  • Open Access
    Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle
    Roselyne Castonguay, Jennifer Lachey, Samantha Wallner, Jamie Strand, Katia Liharska, Abigail E. Watanabe, Marishka Cannell, Monique V. Davies, Dianne Sako, Megan E. Troy, Lavanya Krishnan, Aaron W. Mulivor, Huiming Li, Sarah Keates, Mark J. Alexander, R. Scott Pearsall and Ravi Kumar
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 435-445; DOI: https://doi.org/10.1124/jpet.118.252304

Inflammation, Immunopharmacology, and Asthma

  • You have access
    Cinobufacini Ameliorates Dextran Sulfate Sodium–Induced Colitis in Mice through Inhibiting M1 Macrophage Polarization
    Si-wei Wang, Yong-feng Bai, Yuan-yuan Weng, Xue-yu Fan, Hui Huang, Fang Zheng, Yi Xu and Feng Zhang
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 391-400; DOI: https://doi.org/10.1124/jpet.118.254516
  • You have access
    Antibody Dependent Enhancement of Acinetobacter baumannii Infection in a Mouse Pneumonia Model
    Shun Xin Wang-Lin, Ruth Olson, Janet M. Beanan, Ulrike MacDonald, Thomas A. Russo and Joseph P. Balthasar
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 475-489; DOI: https://doi.org/10.1124/jpet.118.253617

Metabolism, Transport, and Pharmacogenomics

  • You have access
    The HNF1α-Regulated LncRNA HNF1α-AS1 Is Involved in the Regulation of Cytochrome P450 Expression in Human Liver Tissues and Huh7 Cells
    Yiting Wang, Liang Yan, Jingyang Liu, Shitong Chen, Guangming Liu, Yali Nie, Pei Wang, Weihong Yang, Liming Chen, Xiaobo Zhong, Shengna Han and Lirong Zhang
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 353-362; DOI: https://doi.org/10.1124/jpet.118.252940
  • You have access
    Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma
    Dong Gui Hu, Shashikanth Marri, Ross A. McKinnon, Peter I. Mackenzie and Robyn Meech
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 363-381; DOI: https://doi.org/10.1124/jpet.118.255018
  • You have access
    Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases
    Gautham Gampa, Minjee Kim, Afroz S. Mohammad, Karen E. Parrish, Ann C. Mladek, Jann N. Sarkaria and William F. Elmquist
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 446-461; DOI: https://doi.org/10.1124/jpet.118.253708
  • Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice
    You have access
    Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice
    Antari Khot, Satoko Matsueda, Veena A. Thomas, Richard C. Koya and Dhaval K. Shah
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 503-513; DOI: https://doi.org/10.1124/jpet.118.252858

Neuropharmacology

  • You have access
    Intravenously Administered Ganaxolone Blocks Diazepam-Resistant Lithium-Pilocarpine–Induced Status Epilepticus in Rats: Comparison with Allopregnanolone
    Michael S. Saporito, John A. Gruner, Amy DiCamillo, Richard Hinchliffe, Melissa Barker-Haliski and H. Steven White
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 326-337; DOI: https://doi.org/10.1124/jpet.118.252155
  • You have access
    Neutral Sphingomyelinase Inhibition Alleviates LPS-Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury
    Asit Kumar, Rebecca J. Henry, Bogdan A. Stoica, David J. Loane, Gelareh Abulwerdi, Shahnawaz A. Bhat and Alan I. Faden
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 338-352; DOI: https://doi.org/10.1124/jpet.118.253955
  • Open Access
    In Vivo Preclinical Molecular Imaging of Repeated Exposure to an N-methyl-d-aspartate Antagonist and a Glutaminase Inhibitor as Potential Glutamatergic Modulators
    Stijn Servaes, Firat Kara, Dorien Glorie, Sigrid Stroobants, Annemie Van Der Linden and Steven Staelens
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 382-390; DOI: https://doi.org/10.1124/jpet.118.252635
  • You have access
    Synergistic Effects of Acetyl-l-Carnitine and Adipose-Derived Stromal Cells on Improving Regenerative Capacity of Acellular Nerve Allograft in Sciatic Nerve Defect
    Ghayour Mohammad-Bagher, Abdolmaleki Arash, Behnam-Rassouli Morteza, Mahdavi-Shahri Naser and Moghimi Ali
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 490-502; DOI: https://doi.org/10.1124/jpet.118.254540
  • You have access
    Inflammatory Macrophages in the Sciatic Nerves Facilitate Neuropathic Pain Associated with Type 2 Diabetes Mellitus
    Fumihiro Saika, Norikazu Kiguchi, Shinsuke Matsuzaki, Daichi Kobayashi and Shiroh Kishioka
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 535-544; DOI: https://doi.org/10.1124/jpet.118.252668

Erratum

  • You have access
    Correction to “Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance”
    Journal of Pharmacology and Experimental Therapeutics March 2019, 368 (3) 474; DOI: https://doi.org/10.1124/jpet.117.251413err
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 368 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 368, Issue 3
1 Mar 2019
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Cardiovascular
  • Cellular and Molecular
  • Drug Discovery and Translational Medicine
  • Inflammation, Immunopharmacology, and Asthma
  • Metabolism, Transport, and Pharmacogenomics
  • Neuropharmacology
  • Erratum
  • Most Cited
  • Most Read
Loading
  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics