Research ArticleDrug Discovery and Translational Medicine
Development of Human Target Validation Classification that Predicts Future Clinical Efficacy
Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894
Cecilia Karlsson
Cardiovascular, Renal and Metabolism Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (C.K., P.J.G.); Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (C.K.); Emeriti Pharma, AZ Bioventure Hub, Gothenburg, Sweden (D.G.); and KW Translational Medicine AB, Västra Frölunda, Sweden (K.W.)
Peter J. Greasley
Cardiovascular, Renal and Metabolism Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (C.K., P.J.G.); Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (C.K.); Emeriti Pharma, AZ Bioventure Hub, Gothenburg, Sweden (D.G.); and KW Translational Medicine AB, Västra Frölunda, Sweden (K.W.)
David Gustafsson
Cardiovascular, Renal and Metabolism Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (C.K., P.J.G.); Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (C.K.); Emeriti Pharma, AZ Bioventure Hub, Gothenburg, Sweden (D.G.); and KW Translational Medicine AB, Västra Frölunda, Sweden (K.W.)
Karin Wåhlander
Cardiovascular, Renal and Metabolism Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden (C.K., P.J.G.); Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (C.K.); Emeriti Pharma, AZ Bioventure Hub, Gothenburg, Sweden (D.G.); and KW Translational Medicine AB, Västra Frölunda, Sweden (K.W.)

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Research ArticleDrug Discovery and Translational Medicine
Human Target Validation Classification Predicts Efficacy
Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
Journal of Pharmacology and Experimental Therapeutics February 1, 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894
Research ArticleDrug Discovery and Translational Medicine
Human Target Validation Classification Predicts Efficacy
Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
Journal of Pharmacology and Experimental Therapeutics February 1, 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894
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