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Index by author

February 01, 2019; Volume 368,Issue 2

A

  1. Abdel-Rahman, Abdel A.

    1. Estrogen-Dependent Disruption of Adiponectin-Connexin43 Signaling Underlies Exacerbated Myocardial Dysfunction in Diabetic Female Rats
      Korin E. Leffler and Abdel A. Abdel-Rahman
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 208-217; DOI: https://doi.org/10.1124/jpet.118.254029

  2. Ahmad, Ashfaq

    1. Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor
      Zdravka Daneva, Sara K. Dempsey, Ashfaq Ahmad, Ningjun Li, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 187-198; DOI: https://doi.org/10.1124/jpet.118.252320

  3. Allen, Daicia C.

    1. A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
      Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

  4. Alsharif, Walid F.

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

  5. Asprodini, E.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

B

  1. Baruffaldi, Federico

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

  2. Begas, E.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

  3. Bonnen, Mark D.

    1. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes
      Afshin Ebrahimpour, Samana Shrestha, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu and Yohannes T. Ghebre
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 169-178; DOI: https://doi.org/10.1124/jpet.118.252650

  4. Bowen, Wayne D.

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

C

  1. Carlson, Timothy L.

    1. A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
      Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

  2. Chan, Chi-Chung

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  3. Cheung, Mui

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  4. Comeau, Anthony B.

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

  5. Crane, Jasmine

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

  6. Cuzon Carlson, Verginia C.

    1. A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
      Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

D

  1. Daneva, Zdravka

    1. Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor
      Zdravka Daneva, Sara K. Dempsey, Ashfaq Ahmad, Ningjun Li, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 187-198; DOI: https://doi.org/10.1124/jpet.118.252320

  2. Darwich, Adam S.

    1. Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance
      Takanobu Matsuzaki, Daniel Scotcher, Adam S. Darwich, Aleksandra Galetin and Amin Rostami-Hodjegan
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 157-168; DOI: https://doi.org/10.1124/jpet.118.251413

  3. DeMartino, Michael P.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  4. Dempsey, Sara K.

    1. Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor
      Zdravka Daneva, Sara K. Dempsey, Ashfaq Ahmad, Ningjun Li, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 187-198; DOI: https://doi.org/10.1124/jpet.118.252320

  5. Disney, Alex

    1. Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
      Lisa R. Gerak, David R. Maguire, James H. Woods, Stephen M. Husbands, Alex Disney and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 229-236; DOI: https://doi.org/10.1124/jpet.118.253286

  6. Doi, Takefumi

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

E

  1. Ebrahimpour, Afshin

    1. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes
      Afshin Ebrahimpour, Samana Shrestha, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu and Yohannes T. Ghebre
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 169-178; DOI: https://doi.org/10.1124/jpet.118.252650

  2. Eidam, Hilary S.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  3. Eissa, N. Tony

    1. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes
      Afshin Ebrahimpour, Samana Shrestha, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu and Yohannes T. Ghebre
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 169-178; DOI: https://doi.org/10.1124/jpet.118.252650

  4. Ewing, Laura

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

F

  1. Fan, Kai-Jian

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

  2. Fantegrossi, William E.

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

  3. France, Charles P.

    1. Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
      Lisa R. Gerak, David R. Maguire, James H. Woods, Stephen M. Husbands, Alex Disney and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 229-236; DOI: https://doi.org/10.1124/jpet.118.253286

  4. Fujiwara, Ryochi

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

G

  1. Galetin, Aleksandra

    1. Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance
      Takanobu Matsuzaki, Daniel Scotcher, Adam S. Darwich, Aleksandra Galetin and Amin Rostami-Hodjegan
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 157-168; DOI: https://doi.org/10.1124/jpet.118.251413

  2. Gáspár, Róbert

    1. α-Tocopherol Potentiates the Cervical Resistance Decreasing Effects of COX Inhibitors in Pregnant Rats: The Putative Role of Cyclooxygenase-2 Inhibition
      Anna Kothencz, Judit Hajagos-Tóth, Kálmán F. Szűcs, Annamária Schaffer and Róbert Gáspár
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 292-298; DOI: https://doi.org/10.1124/jpet.118.251850

  3. Gerak, Lisa R.

    1. Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
      Lisa R. Gerak, David R. Maguire, James H. Woods, Stephen M. Husbands, Alex Disney and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 229-236; DOI: https://doi.org/10.1124/jpet.118.253286

  4. Gershon, Michael D.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  5. Ghebre, Yohannes T.

    1. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes
      Afshin Ebrahimpour, Samana Shrestha, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu and Yohannes T. Ghebre
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 169-178; DOI: https://doi.org/10.1124/jpet.118.252650

  6. Grant, Kathleen A.

    1. A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
      Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

  7. Greasley, Peter J.

    1. Development of Human Target Validation Classification that Predicts Future Clinical Efficacy
      Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894

  8. Greenwood-Van Meerveld, Beverley

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  9. Gustafsson, David

    1. Development of Human Target Validation Classification that Predicts Future Clinical Efficacy
      Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894

H

  1. Hajagos-Tóth, Judit

    1. α-Tocopherol Potentiates the Cervical Resistance Decreasing Effects of COX Inhibitors in Pregnant Rats: The Putative Role of Cyclooxygenase-2 Inhibition
      Anna Kothencz, Judit Hajagos-Tóth, Kálmán F. Szűcs, Annamária Schaffer and Róbert Gáspár
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 292-298; DOI: https://doi.org/10.1124/jpet.118.251850

  2. Hanenberg, Helmut

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  3. Harmon, Theresa M.

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

  4. Hashimoto, Yosuke

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  5. Hong, Yanguo

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

  6. Huang, Jianzhong

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

  7. Husbands, Stephen M.

    1. Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
      Lisa R. Gerak, David R. Maguire, James H. Woods, Stephen M. Husbands, Alex Disney and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 229-236; DOI: https://doi.org/10.1124/jpet.118.253286

I

  1. Intagliata, Sebastiano

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

J

  1. Jin, Jian

    1. A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
      Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

  2. Johnson, Anthony C.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

K

  1. Karlsson, Cecilia

    1. Development of Human Target Validation Classification that Predicts Future Clinical Efficacy
      Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894

  2. Kilindris, T.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

  3. Komori, Hisakazu

    1. Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport
      Takeo Nakanishi, Hiroki Takashima, Yuka Uetoko, Hisakazu Komori and Ikumi Tamai
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 317-325; DOI: https://doi.org/10.1124/jpet.118.249789

  4. Kondoh, Masuo

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  5. Kothencz, Anna

    1. α-Tocopherol Potentiates the Cervical Resistance Decreasing Effects of COX Inhibitors in Pregnant Rats: The Putative Role of Cyclooxygenase-2 Inhibition
      Anna Kothencz, Judit Hajagos-Tóth, Kálmán F. Szűcs, Annamária Schaffer and Róbert Gáspár
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 292-298; DOI: https://doi.org/10.1124/jpet.118.251850

  6. Kouvaras, E.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

  7. Kowalski, John P.

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  8. Kumar, Sanjay

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

L

  1. Leffler, Korin E.

    1. Estrogen-Dependent Disruption of Adiponectin-Connexin43 Signaling Underlies Exacerbated Myocardial Dysfunction in Diabetic Female Rats
      Korin E. Leffler and Abdel A. Abdel-Rahman
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 208-217; DOI: https://doi.org/10.1124/jpet.118.254029

  2. Le Naour, Morgan

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

  3. Li, Ningjun

    1. Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor
      Zdravka Daneva, Sara K. Dempsey, Ashfaq Ahmad, Ningjun Li, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 187-198; DOI: https://doi.org/10.1124/jpet.118.252320

  4. Li, Pin-Lan

    1. Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor
      Zdravka Daneva, Sara K. Dempsey, Ashfaq Ahmad, Ningjun Li, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 187-198; DOI: https://doi.org/10.1124/jpet.118.252320

  5. Li, Qi

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

  6. Ligon, Casey O.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  7. Lin, Mingyan

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

  8. Lockhart, Taylor

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

  9. Lu, Qiuhua

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

M

  1. Maguire, David R.

    1. Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
      Lisa R. Gerak, David R. Maguire, James H. Woods, Stephen M. Husbands, Alex Disney and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 229-236; DOI: https://doi.org/10.1124/jpet.118.253286

  2. Matsuzaki, Takanobu

    1. Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance
      Takanobu Matsuzaki, Daniel Scotcher, Adam S. Darwich, Aleksandra Galetin and Amin Rostami-Hodjegan
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 157-168; DOI: https://doi.org/10.1124/jpet.118.251413

  3. McCurdy, Christopher R.

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

  4. McDonald, Matthew G.

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  5. Mesangeau, Christophe

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

  6. Messinis, I.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

  7. Mohammadi, Ehsan

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  8. Mori, Yasuo

    1. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
      Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori and Shunichi Shimizu
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 246-254; DOI: https://doi.org/10.1124/jpet.118.253922

  9. Mottinelli, Marco

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

N

  1. Nakanishi, Takeo

    1. Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport
      Takeo Nakanishi, Hiroki Takashima, Yuka Uetoko, Hisakazu Komori and Ikumi Tamai
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 317-325; DOI: https://doi.org/10.1124/jpet.118.249789

  2. Nicholson, Hilary E.

    1. Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives
      Hilary E. Nicholson, Walid F. Alsharif, Anthony B. Comeau, Christophe Mesangeau, Sebastiano Intagliata, Marco Mottinelli, Christopher R. McCurdy and Wayne D. Bowen
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 272-281; DOI: https://doi.org/10.1124/jpet.118.253484

O

  1. Okada, Yoshiaki

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  2. Oliff, Allen I.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

P

  1. Parkinson, Oliver T.

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  2. Pentel, Paul R.

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

  3. Peterson, Samantha J.

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

  4. Pravetoni, Marco

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

R

  1. Radominska-Pandya, Anna

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

  2. Raghu, Ganesh

    1. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes
      Afshin Ebrahimpour, Samana Shrestha, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu and Yohannes T. Ghebre
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 169-178; DOI: https://doi.org/10.1124/jpet.118.252650

  3. Raleigh, Michael D.

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

  4. Rao, Meenakshi

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  5. Rettie, Allan E.

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  6. Ritter, Joseph K.

    1. Diuretic, Natriuretic, and Vasodepressor Activity of a Lipid Fraction Enhanced in Medium of Cultured Mouse Medullary Interstitial Cells by a Selective Fatty Acid Amide Hydrolase Inhibitor
      Zdravka Daneva, Sara K. Dempsey, Ashfaq Ahmad, Ningjun Li, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 187-198; DOI: https://doi.org/10.1124/jpet.118.252320

  7. Roellecke, Katharina

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  8. Rostami-Hodjegan, Amin

    1. Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance
      Takanobu Matsuzaki, Daniel Scotcher, Adam S. Darwich, Aleksandra Galetin and Amin Rostami-Hodjegan
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 157-168; DOI: https://doi.org/10.1124/jpet.118.251413

  9. Russell, John P.

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

S

  1. Samara, M.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

  2. Sawada, Makoto

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  3. Schaffer, Annamária

    1. α-Tocopherol Potentiates the Cervical Resistance Decreasing Effects of COX Inhibitors in Pregnant Rats: The Putative Role of Cyclooxygenase-2 Inhibition
      Anna Kothencz, Judit Hajagos-Tóth, Kálmán F. Szűcs, Annamária Schaffer and Róbert Gáspár
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 292-298; DOI: https://doi.org/10.1124/jpet.118.251850

  4. Scian, Michele

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  5. Scotcher, Daniel

    1. Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance
      Takanobu Matsuzaki, Daniel Scotcher, Adam S. Darwich, Aleksandra Galetin and Amin Rostami-Hodjegan
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 157-168; DOI: https://doi.org/10.1124/jpet.118.251413

  6. Shen, Yuhong

    1. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity
      John P. Russell, Ehsan Mohammadi, Casey O. Ligon, Anthony C. Johnson, Michael D. Gershon, Meenakshi Rao, Yuhong Shen, Chi-Chung Chan, Hilary S. Eidam, Michael P. DeMartino, Mui Cheung, Allen I. Oliff, Sanjay Kumar and Beverley Greenwood-Van Meerveld
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 299-307; DOI: https://doi.org/10.1124/jpet.118.252973

  7. Shimizu, Shunichi

    1. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
      Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori and Shunichi Shimizu
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 246-254; DOI: https://doi.org/10.1124/jpet.118.253922

  8. Shirakura, Keisuke

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  9. Shrestha, Samana

    1. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes
      Afshin Ebrahimpour, Samana Shrestha, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu and Yohannes T. Ghebre
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 169-178; DOI: https://doi.org/10.1124/jpet.118.252650

  10. Szűcs, Kálmán F.

    1. α-Tocopherol Potentiates the Cervical Resistance Decreasing Effects of COX Inhibitors in Pregnant Rats: The Putative Role of Cyclooxygenase-2 Inhibition
      Anna Kothencz, Judit Hajagos-Tóth, Kálmán F. Szűcs, Annamária Schaffer and Róbert Gáspár
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 292-298; DOI: https://doi.org/10.1124/jpet.118.251850

T

  1. Tachibana, Keisuke

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  2. Tai, Sherrica

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

  3. Takashima, Hiroki

    1. Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport
      Takeo Nakanishi, Hiroki Takashima, Yuka Uetoko, Hisakazu Komori and Ikumi Tamai
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 317-325; DOI: https://doi.org/10.1124/jpet.118.249789

  4. Tamai, Ikumi

    1. Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport
      Takeo Nakanishi, Hiroki Takashima, Yuka Uetoko, Hisakazu Komori and Ikumi Tamai
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 317-325; DOI: https://doi.org/10.1124/jpet.118.249789

  5. Tang, Ting-Ting

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

  6. Teitelbaum, Aaron M.

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  7. Toda, Takahiro

    1. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
      Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori and Shunichi Shimizu
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 246-254; DOI: https://doi.org/10.1124/jpet.118.253922

  8. Tsiokou, V.

    1. Alterations in Xenobiotic-Metabolizing Enzyme Activities across Menstrual Cycle in Healthy Volunteers
      E. Asprodini, V. Tsiokou, E. Begas, T. Kilindris, E. Kouvaras, M. Samara and I. Messinis
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 262-271; DOI: https://doi.org/10.1124/jpet.118.254284

U

  1. Uetoko, Yuka

    1. Experimental Evidence for Resecretion of PGE2 across Rat Alveolar Epithelium by OATP2A1/SLCO2A1-Mediated Transcellular Transport
      Takeo Nakanishi, Hiroki Takashima, Yuka Uetoko, Hisakazu Komori and Ikumi Tamai
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 317-325; DOI: https://doi.org/10.1124/jpet.118.249789

  2. Umehara, Noriko

    1. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
      Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori and Shunichi Shimizu
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 246-254; DOI: https://doi.org/10.1124/jpet.118.253922

V

  1. Vigliaturo, Jennifer R.

    1. A Fentanyl Vaccine Alters Fentanyl Distribution and Protects against Fentanyl-Induced Effects in Mice and Rats
      Michael D. Raleigh, Federico Baruffaldi, Samantha J. Peterson, Morgan Le Naour, Theresa M. Harmon, Jennifer R. Vigliaturo, Paul R. Pentel and Marco Pravetoni
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 282-291; DOI: https://doi.org/10.1124/jpet.118.253674

W

  1. Wåhlander, Karin

    1. Development of Human Target Validation Classification that Predicts Future Clinical Efficacy
      Cecilia Karlsson, Peter J. Greasley, David Gustafsson and Karin Wåhlander
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 255-261; DOI: https://doi.org/10.1124/jpet.118.250894

  2. Wakamori, Minoru

    1. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
      Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori and Shunichi Shimizu
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 246-254; DOI: https://doi.org/10.1124/jpet.118.253922

  3. Wang, Mei

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

  4. Wang, Qi-Shan

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

  5. Wang, Ting-Yu

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

  6. Whittington, Dale

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  7. Wiek, Constanze

    1. Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol
      Aaron M. Teitelbaum, Matthew G. McDonald, John P. Kowalski, Oliver T. Parkinson, Michele Scian, Dale Whittington, Katharina Roellecke, Helmut Hanenberg, Constanze Wiek and Allan E. Rettie
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 308-316; DOI: https://doi.org/10.1124/jpet.118.249771

  8. Wilson, Catheryn D.

    1. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice
      Catheryn D. Wilson, Sherrica Tai, Laura Ewing, Jasmine Crane, Taylor Lockhart, Ryochi Fujiwara, Anna Radominska-Pandya and William E. Fantegrossi
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 146-156; DOI: https://doi.org/10.1124/jpet.118.251157

  9. Woods, James H.

    1. Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
      Lisa R. Gerak, David R. Maguire, James H. Woods, Stephen M. Husbands, Alex Disney and Charles P. France
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 229-236; DOI: https://doi.org/10.1124/jpet.118.253286

  10. Wu, Jing

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

X

  1. Xiong, Yan

    1. A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
      Daicia C. Allen, Timothy L. Carlson, Yan Xiong, Jian Jin, Kathleen A. Grant and Verginia C. Cuzon Carlson
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 199-207; DOI: https://doi.org/10.1124/jpet.118.252031

  2. Xu, Bing-Xing

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

Y

  1. Yagi, Kiyohito

    1. Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs
      Yosuke Hashimoto, Yoshiaki Okada, Keisuke Shirakura, Keisuke Tachibana, Makoto Sawada, Kiyohito Yagi, Takefumi Doi and Masuo Kondoh
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 179-186; DOI: https://doi.org/10.1124/jpet.118.252361

  2. Yamamoto, Shinichiro

    1. Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
      Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori and Shunichi Shimizu
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 246-254; DOI: https://doi.org/10.1124/jpet.118.253922

Z

  1. Zhang, Jun

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369

  2. Zhang, Yunshan

    1. Inhibitory Effects of Mas-Related Gene C Receptor on Chronic Morphine-Induced Spinal Glial Activation in Rats
      Yunshan Zhang, Mei Wang, Qiuhua Lu, Qi Li, Mingyan Lin, Jianzhong Huang and Yanguo Hong
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 237-245; DOI: https://doi.org/10.1124/jpet.118.252494

  3. Zhao, Fu-Tao

    1. Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-<em>κ</em>B Signaling in Rats with Collagen-Induced Arthritis
      Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis
      Jing Wu, Fu-Tao Zhao, Kai-Jian Fan, Jun Zhang, Bing-Xing Xu, Qi-Shan Wang, Ting-Ting Tang and Ting-Yu Wang
      Journal of Pharmacology and Experimental Therapeutics February 2019, 368 (2) 218-228; DOI: https://doi.org/10.1124/jpet.118.253369
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