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Research ArticleMinireviews

Genetic Association of Single Nucleotide Polymorphisms with Acetaminophen-Induced Hepatotoxicity

Daniel P. Heruth, Katherine Shortt, Nini Zhang, Ding-You Li, Li Q. Zhang and Shui Qing Ye
Journal of Pharmacology and Experimental Therapeutics October 2018, 367 (1) 95-100; DOI: https://doi.org/10.1124/jpet.118.248583
Daniel P. Heruth
Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
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Katherine Shortt
Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
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Nini Zhang
Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
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Ding-You Li
Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
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Li Q. Zhang
Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
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Shui Qing Ye
Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
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Article Information

vol. 367 no. 1 95-100
DOI 
https://doi.org/10.1124/jpet.118.248583
PubMed 
30076262

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 18, 2018
  • Accepted August 1, 2018
  • Published online September 10, 2018.

Article Versions

  • Earlier version (August 3, 2018 - 09:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Daniel P. Heruth,
  2. Katherine Shortt,
  3. Nini Zhang,
  4. Ding-You Li,
  5. Li Q. Zhang, and
  6. Shui Qing Ye
  1. Division of Experimental and Translational Genetics, Department of Pediatrics, Children’s Mercy (D.P.H., K.S., N.Z., L.Q.Z., S.Q.Y.), Division of Gastroenterology, Department of Pediatrics, Children’s Mercy (N.Z., D.-Y.L.), and Department of Biomedical and Health Informatics (K.S., S.Q.Y.), University of Missouri Kansas City School of Medicine, Kansas City, Missouri; Division of Cell Biology and Biophysics, University of Missouri Kansas City School of Biological Sciences, Kansas City, Missouri (K.S.); and Department of Pediatrics, Tangdu Hospital, The Fourth Military Medical University, Xian, China (N.Z.)
  1. Address correspondence to:
    Dr. Daniel P. Heruth, Children’s Mercy, 2601 Gillham Road, Kansas City, MO 64068. E-mail: dpheruth{at}cmh.edu
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Journal of Pharmacology and Experimental Therapeutics: 367 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 367, Issue 1
1 Oct 2018
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Research ArticleMinireviews

SNPs Associated with Acetaminophen-Induced Hepatotoxicity

Daniel P. Heruth, Katherine Shortt, Nini Zhang, Ding-You Li, Li Q. Zhang and Shui Qing Ye
Journal of Pharmacology and Experimental Therapeutics October 1, 2018, 367 (1) 95-100; DOI: https://doi.org/10.1124/jpet.118.248583

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Research ArticleMinireviews

SNPs Associated with Acetaminophen-Induced Hepatotoxicity

Daniel P. Heruth, Katherine Shortt, Nini Zhang, Ding-You Li, Li Q. Zhang and Shui Qing Ye
Journal of Pharmacology and Experimental Therapeutics October 1, 2018, 367 (1) 95-100; DOI: https://doi.org/10.1124/jpet.118.248583
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