Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana

Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology (S.P.B.S.P., K.S., R.S.S., B.P., T.S., T.W.C.), Department of Pharmacology and Toxicology (R.S.S., B.P., T.S., M.L.F., M.R.K., T.W.C.), Department of Biochemistry and Molecular Biology (M.R.K., T.W.C.), Herman B Wells Center for Pediatric Research, Department of Pediatrics (F.S., M.L.F., M.R.K.), and Melvin and Bren Simon Cancer Center (M.L.F., M.R.K., T.W.C.), Indiana University School of Medicine, Indianapolis, Indiana; and Apexian Pharmaceuticals (J.H.W.), Indianapolis, Indiana