Journal of Pharmacology and Experimental Therapeutics: 366 (3)

September 01, 2018; Volume 366,Issue 3

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Neuroprotective Effects of Nicotine on Hippocampal Long-Term Potentiation in Brain Disorders
Karim A. Alkadhi

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 498-508; DOI: https://doi.org/10.1124/jpet.118.247841
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Dopamine D₂ Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders
Richard M. Kostrzewa, Karolina Wydra, Malgorzata Filip, Cynthia A. Crawford, Sanders A. McDougall, Russell W. Brown, Dasiel O. Borroto-Escuela, Kjell Fuxe and Raul R. Gainetdinov

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 519-526; DOI: https://doi.org/10.1124/jpet.118.247981

Cardiovascular

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Calcitriol Accelerates Vascular Calcification Irrespective of Vitamin K Status in a Rat Model of Chronic Kidney Disease with Hyperphosphatemia and Secondary Hyperparathyroidism
Kristin M. McCabe, Jason G. Zelt, Martin Kaufmann, Kimberly Laverty, Emilie Ward, Henry Barron, Glenville Jones, Michael A. Adams and Rachel M. Holden

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 433-445; DOI: https://doi.org/10.1124/jpet.117.247270
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Contributions of Nrf2 to Puerarin Prevention of Cardiac Hypertrophy and its Metabolic Enzymes Expression in Rats
Gan-Jian Zhao, Ning Hou, Shao-Ai Cai, Xia-Wen Liu, Ai-Qun Li, Chuan-Fang Cheng, Yin Huang, Li-Rong Li, Yun-Pei Mai, Shi-Ming Liu, Cai-Wen Ou, Zhen-Yu Xiong, Xiao-Hui Chen, Min-Sheng Chen and Cheng-Feng Luo

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 458-469; DOI: https://doi.org/10.1124/jpet.118.248369

Chemotherapy, Antibiotics, and Gene Therapy

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Antagonizing SET Augments the Effects of Radiation Therapy in Hepatocellular Carcinoma through Reactivation of PP2A-Mediated Akt Downregulation
Chao-Yuan Huang, Man-Hsin Hung, Chi-Ting Shih, Feng-Shu Hsieh, Chiung-Wen Kuo, Ming-Hsien Tsai, Shih-Shin Chang, Yung-Jen Hsiao, Li-Ju Chen, Tzu-I. Chao and Kuen-Feng Chen

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 410-421; DOI: https://doi.org/10.1124/jpet.118.249102
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Efavirenz and Lopinavir Levels in HIV-Infected Women and Their Nursing Infants, in Mali
Aboubacar Alassane Oumar, Kadiatou Bagayoko-Maiga, Aliou Bahachimi, Mamoudou Maiga, Marie-Christine Cere, Zoumana Diarra, Etienne Chatelut, Mariam Sylla, Robert Leo Murphy, Sounkalo Dao and Peggy Gandia

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 479-484; DOI: https://doi.org/10.1124/jpet.118.249938

Drug Discovery and Translational Medicine

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In Vitro and In Vivo Characterization of Novel Stable Peptidic Ghrelin Analogs: Beneficial Effects in the Settings of Lipopolysaccharide-Induced Anorexia in Mice
Martina Holubová, Miroslava Blechová, Anna Kákonová, Jaroslav Kuneš, Blanka Železná and Lenka Maletínská

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 422-432; DOI: https://doi.org/10.1124/jpet.118.249086

Metabolism, Transport, and Pharmacogenomics

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A Specific Probe Substrate for Evaluation of CYP4A11 Activity in Human Tissue Microsomes and a Highly Selective CYP4A11 Inhibitor: Luciferin-4A and Epalrestat
Satoshi Yamaori, Noriyuki Araki, Mio Shionoiri, Kurumi Ikehata, Shinobu Kamijo, Shigeru Ohmori and Kazuhito Watanabe

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 446-457; DOI: https://doi.org/10.1124/jpet.118.249557

Neuropharmacology

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Honokiol Ameliorates Amyloidosis and Neuroinflammation and Improves Cognitive Impairment in Alzheimer’s Disease Transgenic Mice
Dongmei Wang, Xiaohui Dong and Chenying Wang

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 470-478; DOI: https://doi.org/10.1124/jpet.118.248674
Open Access
NYX-2925 Is a Novel N-Methyl-d-Aspartate Receptor Modulator that Induces Rapid and Long-Lasting Analgesia in Rat Models of Neuropathic Pain
Nayereh Ghoreishi-Haack, Jessica M. Priebe, Jacqueline D. Aguado, Elizabeth M. Colechio, Jeffrey S. Burgdorf, M. Scott Bowers, Cassia N. Cearley, M. Amin Khan and Joseph R. Moskal

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 485-497; DOI: https://doi.org/10.1124/jpet.118.249409
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Differential Tolerance to FTY720-Induced Antinociception in Acute Thermal and Nerve Injury Mouse Pain Models: Role of Sphingosine-1-Phosphate Receptor Adaptation
Laura J. Sim-Selley, Jenny L. Wilkerson, James J. Burston, Kurt F. Hauser, Virginia McLane, Sandra P. Welch, Aron H. Lichtman and Dana E. Selley

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 509-518; DOI: https://doi.org/10.1124/jpet.118.248260
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Dopamine Transporter Dynamics of N-Substituted Benztropine Analogs with Atypical Behavioral Effects
Weimin C. Hong, Michael J. Wasko, Derek S. Wilkinson, Takato Hiranita, Libin Li, Shuichiro Hayashi, David B. Snell, Jeffry D. Madura, Christopher K. Surratt and Jonathan L. Katz

Journal of Pharmacology and Experimental Therapeutics September 2018, 366 (3) 527-540; DOI: https://doi.org/10.1124/jpet.118.250498

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Minireviews

Cardiovascular

Chemotherapy, Antibiotics, and Gene Therapy

Drug Discovery and Translational Medicine

Metabolism, Transport, and Pharmacogenomics

Neuropharmacology

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