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Research ArticleDrug Discovery and Translational Medicine

Novel Polyphenols That Inhibit Colon Cancer Cell Growth Affecting Cancer Cell Metabolism

Marta Gómez de Cedrón, Teodoro Vargas, Andrés Madrona, Aranza Jiménez, María-Jesús Pérez-Pérez, José-Carlos Quintela, Guillermo Reglero, Ana San-Félix and Ana Ramírez de Molina
Journal of Pharmacology and Experimental Therapeutics August 2018, 366 (2) 377-389; DOI: https://doi.org/10.1124/jpet.118.248278
Marta Gómez de Cedrón
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Teodoro Vargas
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Andrés Madrona
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Aranza Jiménez
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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María-Jesús Pérez-Pérez
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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José-Carlos Quintela
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Guillermo Reglero
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Ana San-Félix
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Ana Ramírez de Molina
Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
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Article Information

vol. 366 no. 2 377-389
DOI 
https://doi.org/10.1124/jpet.118.248278
PubMed 
29871992

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 19, 2018
  • Accepted June 1, 2018
  • Published online July 16, 2018.

Article Versions

  • Earlier version (June 5, 2018 - 12:11).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Marta Gómez de Cedrón,
  2. Teodoro Vargas,
  3. Andrés Madrona1,
  4. Aranza Jiménez2,
  5. María-Jesús Pérez-Pérez,
  6. José-Carlos Quintela,
  7. Guillermo Reglero,
  8. Ana San-Félix, and
  9. Ana Ramírez de Molina
  1. Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain (M.G.d.C., T.V., G.R., A.R.d.M.); Instituto de Química Médica (IQM, CSIC), Juan de la Cierva 3, Madrid, Spain (A.M., A.J., M.-J.P.-P., A.S.-F.); and Natac Biotech S.L., Parque Científico de Madrid, Campus de Cantoblanco, Madrid, Spain (J.-C.Q.)
  1. Address correspondence to:
    Ana Ramírez de Molina, IMDEA Food Institute, Crta. Cantoblanco 8, 28049, Madrid, Spain. E-mail: ana.ramirez{at}imdea.org; or
  2. Ana San-Félix, Instituto de Química Médica (IQM-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain. E-mail: anarosa{at}iqm.csic.es
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Journal of Pharmacology and Experimental Therapeutics: 366 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 366, Issue 2
1 Aug 2018
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Research ArticleDrug Discovery and Translational Medicine

Polyphenols Targeting Cancer Cell Metabolism

Marta Gómez de Cedrón, Teodoro Vargas, Andrés Madrona, Aranza Jiménez, María-Jesús Pérez-Pérez, José-Carlos Quintela, Guillermo Reglero, Ana San-Félix and Ana Ramírez de Molina
Journal of Pharmacology and Experimental Therapeutics August 1, 2018, 366 (2) 377-389; DOI: https://doi.org/10.1124/jpet.118.248278

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Research ArticleDrug Discovery and Translational Medicine

Polyphenols Targeting Cancer Cell Metabolism

Marta Gómez de Cedrón, Teodoro Vargas, Andrés Madrona, Aranza Jiménez, María-Jesús Pérez-Pérez, José-Carlos Quintela, Guillermo Reglero, Ana San-Félix and Ana Ramírez de Molina
Journal of Pharmacology and Experimental Therapeutics August 1, 2018, 366 (2) 377-389; DOI: https://doi.org/10.1124/jpet.118.248278
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