Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn
Research ArticleDrug Discovery and Translational Medicine

Systematic Modeling and Design Evaluation of Unperturbed Tumor Dynamics in Xenografts

Zinnia P. Parra-Guillen, Victor Mangas-Sanjuan, Maria Garcia-Cremades, Iñaki F. Troconiz, Gary Mo, Celine Pitou, Philip W. Iversen and Johan E. Wallin
Journal of Pharmacology and Experimental Therapeutics July 2018, 366 (1) 96-104; DOI: https://doi.org/10.1124/jpet.118.248286
Zinnia P. Parra-Guillen
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Victor Mangas-Sanjuan
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maria Garcia-Cremades
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Iñaki F. Troconiz
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gary Mo
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Celine Pitou
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Philip W. Iversen
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johan E. Wallin
Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Information

vol. 366 no. 1 96-104
DOI 
https://doi.org/10.1124/jpet.118.248286
PubMed 
29691287

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 13, 2018
  • Accepted April 16, 2018
  • Published online June 4, 2018.

Article Versions

  • Earlier version (April 24, 2018 - 07:45).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Zinnia P. Parra-Guillen1,
  2. Victor Mangas-Sanjuan1,2,
  3. Maria Garcia-Cremades3,
  4. Iñaki F. Troconiz,
  5. Gary Mo,
  6. Celine Pitou,
  7. Philip W. Iversen, and
  8. Johan E. Wallin
  1. Pharmacometrics and Systems Pharmacology Research Unit, Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Navarra Institute for Health Research, Pamplona, Spain (Z.P.P.-G.,V.M.-S.,M.G.-C., I.F.T.); Global PK/PD & Pharmacometrics (G.M., C.P., J.E.W.) and Lilly Research Laboratories (P.W.I.), Eli Lilly and Company, Indianapolis, USA Solna, Sweden
  1. Address correspondence to:
    Johan E. Wallin, Eli Lilly and Company, Gustav III Boulevard 42, P.O Box 721, SE 169 27 Solna, Sweden. E-mail: wallinjo{at}lilly.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: April 2018 to January 2023

AbstractFullPdf
Apr 201882035
May 20183722350
Jun 20182522726
Jul 2018581114
Aug 20183835
Sep 20184289
Oct 20183055
Nov 20181886
Dec 20182179
Jan 20191175
Feb 201931317
Mar 20191308
Apr 20193838
May 201918210
Jun 20191059
Jul 201922112
Aug 20191717
Sep 201931816
Oct 201942919
Nov 201993422
Dec 201972111
Jan 20204177
Feb 20201197
Mar 20209277
Apr 20203153
May 202041610
Jun 202022210
Jul 202002721
Aug 2020053
Sep 202061427
Oct 202041719
Nov 202031012
Dec 202031210
Jan 202131715
Feb 202171212
Mar 202116812
Apr 202131111
May 20217206
Jun 202132114
Jul 202131014
Aug 20213719
Sep 20217611
Oct 202121623
Nov 20213917
Dec 20212119
Jan 20223933
Feb 2022879
Mar 20221512
Apr 20222916
May 20222812
Jun 202211111
Jul 2022182
Aug 202251216
Sep 202281026
Oct 20221135
Nov 20224108
Dec 20222714
Jan 2023452

PreviousNext
Back to top

In this issue

Journal of Pharmacology and Experimental Therapeutics: 366 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 366, Issue 1
1 Jul 2018
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Journal of Pharmacology and Experimental Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Systematic Modeling and Design Evaluation of Unperturbed Tumor Dynamics in Xenografts
(Your Name) has forwarded a page to you from Journal of Pharmacology and Experimental Therapeutics
(Your Name) thought you would be interested in this article in Journal of Pharmacology and Experimental Therapeutics.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleDrug Discovery and Translational Medicine

Unperturbed Tumor Growth Modeling and Design

Zinnia P. Parra-Guillen, Victor Mangas-Sanjuan, Maria Garcia-Cremades, Iñaki F. Troconiz, Gary Mo, Celine Pitou, Philip W. Iversen and Johan E. Wallin
Journal of Pharmacology and Experimental Therapeutics July 1, 2018, 366 (1) 96-104; DOI: https://doi.org/10.1124/jpet.118.248286

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleDrug Discovery and Translational Medicine

Unperturbed Tumor Growth Modeling and Design

Zinnia P. Parra-Guillen, Victor Mangas-Sanjuan, Maria Garcia-Cremades, Iñaki F. Troconiz, Gary Mo, Celine Pitou, Philip W. Iversen and Johan E. Wallin
Journal of Pharmacology and Experimental Therapeutics July 1, 2018, 366 (1) 96-104; DOI: https://doi.org/10.1124/jpet.118.248286
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Overview
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Glucose transport modulators and mouse behavioral testing
  • Translational PK/PD Modeling of M3258
  • Kidney protective effects of BI 685509
Show more Drug Discovery and Translational Medicine

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics