Research ArticleNeuropharmacology
Open Access
The Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced Parkinsonism
Sean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. Tjalkens
Journal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Sean L. Hammond
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Katriana A. Popichak
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Xi Li
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Lindsay G. Hunt
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Evan H. Richman
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Pranav U. Damale
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Edwin K. P. Chong
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Donald S. Backos
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Stephen Safe
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
Ronald B. Tjalkens
Department of Environmental and Radiological Health Sciences (S.L.H., K.A.P., L.G.H., E.H.R., R.B.T.) and Department of Electrical and Computer Engineering (P.D., E.C.), Colorado State University, Fort Collins, Colorado; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas (X.L., S.S.); and Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado (D.S.B.)
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Research ArticleNeuropharmacology
Nurr1 Activation Inhibits Gliosis and Protects against MPTP
Sean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. Tjalkens
Journal of Pharmacology and Experimental Therapeutics June 1, 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Research ArticleNeuropharmacology
Nurr1 Activation Inhibits Gliosis and Protects against MPTP
Sean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. Tjalkens
Journal of Pharmacology and Experimental Therapeutics June 1, 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
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