Index by author
June 01, 2018; Volume 365,Issue 3
A
Abd El-Aty, A. M.
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Ahsman, Maurice J.
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Ai, Hong
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Ajami, Nadim J.
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Alam, Asim
- You have accessSepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular NormalizationChristopher S. Rabender, Ninu Bruno, Asim Alam, Gobalakrishnan Sundaresan, Jamal Zweit and Ross B. MikkelsenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 536-543; DOI: https://doi.org/10.1124/jpet.117.245258
Allarà, Marco
- You have accessAnti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact DermatitisStefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone and Vincenzo Di MarzoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI: https://doi.org/10.1124/jpet.117.244368
Arakawa, Naohisa
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Asimus, Sara
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
B
Backos, Donald S.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Banijamali, Ali R.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Barth, Vanessa N.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Batra, Neelu
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Begriche, Karima
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Bernier, Sylvie G.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Bertoletti, Laurent
- You have accessIn Vitro Assessment of Pharmacokinetic Drug-Drug Interactions of Direct Oral Anticoagulants: Type 5-Phosphodiesterase Inhibitors Are Inhibitors of Rivaroxaban and Apixaban Efflux by P-GlycoproteinVictor Margelidon-Cozzolino, Sophie Hodin, Elodie Jacqueroux, Olivier Delézay, Laurent Bertoletti and Xavier DelavenneJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 519-525; DOI: https://doi.org/10.1124/jpet.117.245993
Beshore, Douglas C.
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Bi, Yi-An
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Borde, Annika
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
Broad, Lisa M.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Bruno, Ninu
- You have accessSepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular NormalizationChristopher S. Rabender, Ninu Bruno, Asim Alam, Gobalakrishnan Sundaresan, Jamal Zweit and Ross B. MikkelsenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 536-543; DOI: https://doi.org/10.1124/jpet.117.245258
Bucher, Simon
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Bush, Natasha D.
- You have accessAICAR Prevents Acute Olanzapine-Induced Disturbances in Glucose HomeostasisNatasha D. Bush, Logan K. Townsend and David C. WrightJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 526-535; DOI: https://doi.org/10.1124/jpet.118.248393
C
Cavanaugh, Cassandre
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Chai, Zhonglin
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Chen, Hong-Wu
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Chen, Li-Na
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Chong, Edwin K. P.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Chuang, Shu-Hui
- You have access3β-Methyl-Neurosteroid Analogs Are Preferential Positive Allosteric Modulators and Direct Activators of Extrasynaptic δ-Subunit γ-Aminobutyric Acid Type A Receptors in the Hippocampus Dentate Gyrus SubfieldShu-Hui Chuang and Doodipala Samba ReddyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 583-601; DOI: https://doi.org/10.1124/jpet.117.246660
Cilissen, Caroline
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Clozel, Martine
- Open AccessSelective Prostacyclin Receptor Agonist Selexipag, in Contrast to Prostacyclin Analogs, Does Not Evoke Paradoxical Vasoconstriction of the Rat Femoral ArteryKeith Morrison, Franck Haag, Roland Ernst, Marc Iglarz and Martine ClozelJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 727-733; DOI: https://doi.org/10.1124/jpet.117.246058
Collins, Keagan P.
- You have accessHydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy ModulationKeagan P. Collins, Kristen M. Jackson and Daniel L. GustafsonJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 447-459; DOI: https://doi.org/10.1124/jpet.117.245639
Colvin, Ellen M.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Cooper, Mark E.
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Crabtree, Michael G.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Cunoosamy, Danen
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
Currie, Mark G.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
D
Damale, Pranav U.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Danhof, Meindert
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Delavenne, Xavier
- You have accessIn Vitro Assessment of Pharmacokinetic Drug-Drug Interactions of Direct Oral Anticoagulants: Type 5-Phosphodiesterase Inhibitors Are Inhibitors of Rivaroxaban and Apixaban Efflux by P-GlycoproteinVictor Margelidon-Cozzolino, Sophie Hodin, Elodie Jacqueroux, Olivier Delézay, Laurent Bertoletti and Xavier DelavenneJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 519-525; DOI: https://doi.org/10.1124/jpet.117.245993
Delézay, Olivier
- You have accessIn Vitro Assessment of Pharmacokinetic Drug-Drug Interactions of Direct Oral Anticoagulants: Type 5-Phosphodiesterase Inhibitors Are Inhibitors of Rivaroxaban and Apixaban Efflux by P-GlycoproteinVictor Margelidon-Cozzolino, Sophie Hodin, Elodie Jacqueroux, Olivier Delézay, Laurent Bertoletti and Xavier DelavenneJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 519-525; DOI: https://doi.org/10.1124/jpet.117.245993
Demarest, Keith
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
DeVere White, Ralph W.
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Di Marzo, Vincenzo
- You have accessAnti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact DermatitisStefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone and Vincenzo Di MarzoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI: https://doi.org/10.1124/jpet.117.244368
Domon, Yuki
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Du, Fuyong
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Duan, Zhijian
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
E
Eessalu, Thomas
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Ernst, Roland
- Open AccessSelective Prostacyclin Receptor Agonist Selexipag, in Contrast to Prostacyclin Analogs, Does Not Evoke Paradoxical Vasoconstriction of the Rat Femoral ArteryKeith Morrison, Franck Haag, Roland Ernst, Marc Iglarz and Martine ClozelJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 727-733; DOI: https://doi.org/10.1124/jpet.117.246058
F
Felder, Christian C.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Fox, Steve V.
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Fromenty, Bernard
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Fu, Rong-Guo
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
G
Galetin, Aleksandra
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Gao, Hongying
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Gates, Dana
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Gaubatz, Anne-Rike
- You have accessNew Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) ChannelsConstanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk ThomasJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 614-623; DOI: https://doi.org/10.1124/jpet.118.247692
Gaul, Micheal D.
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Gehlert, Donald
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Germano, Peter
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Goldsmith, Paul J.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Goss, Paul E.
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Guo, Qiang
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Gustafson, Daniel L.
- You have accessHydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy ModulationKeagan P. Collins, Kristen M. Jackson and Daniel L. GustafsonJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 447-459; DOI: https://doi.org/10.1124/jpet.117.245639
H
Haag, Franck
- Open AccessSelective Prostacyclin Receptor Agonist Selexipag, in Contrast to Prostacyclin Analogs, Does Not Evoke Paradoxical Vasoconstriction of the Rat Femoral ArteryKeith Morrison, Franck Haag, Roland Ernst, Marc Iglarz and Martine ClozelJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 727-733; DOI: https://doi.org/10.1124/jpet.117.246058
Hacımüftüoğlu, Ahmet
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Hammock, Bruce D.
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Hammond, Sean L.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Hao, Lei
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Harris, Dawn
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Hegelund-Myrbäck, Tove
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
Hinke, Simon A.
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Ho, Ming-Fen
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Ho, Pui Yan
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Hodin, Sophie
- You have accessIn Vitro Assessment of Pharmacokinetic Drug-Drug Interactions of Direct Oral Anticoagulants: Type 5-Phosphodiesterase Inhibitors Are Inhibitors of Rivaroxaban and Apixaban Efflux by P-GlycoproteinVictor Margelidon-Cozzolino, Sophie Hodin, Elodie Jacqueroux, Olivier Delézay, Laurent Bertoletti and Xavier DelavenneJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 519-525; DOI: https://doi.org/10.1124/jpet.117.245993
Hoët, Delphine
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Hornby, Pamela J.
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Hou, Yuanyuan
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Houston, J. Brian
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Hu, Zihua
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Hunt, Lindsay G.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
I
Iglarz, Marc
- Open AccessSelective Prostacyclin Receptor Agonist Selexipag, in Contrast to Prostacyclin Analogs, Does Not Evoke Paradoxical Vasoconstriction of the Rat Femoral ArteryKeith Morrison, Franck Haag, Roland Ernst, Marc Iglarz and Martine ClozelJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 727-733; DOI: https://doi.org/10.1124/jpet.117.246058
Im, G-Yoon Jamie
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Ingle, James N.
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Inoue, Tatsuya
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Iuvone, Teresa
- You have accessAnti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact DermatitisStefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone and Vincenzo Di MarzoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI: https://doi.org/10.1124/jpet.117.244368
J
Jackson, Kristen M.
- You have accessHydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy ModulationKeagan P. Collins, Kristen M. Jackson and Daniel L. GustafsonJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 447-459; DOI: https://doi.org/10.1124/jpet.117.245639
Jacobson, Sarah
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Jacqueroux, Elodie
- You have accessIn Vitro Assessment of Pharmacokinetic Drug-Drug Interactions of Direct Oral Anticoagulants: Type 5-Phosphodiesterase Inhibitors Are Inhibitors of Rivaroxaban and Apixaban Efflux by P-GlycoproteinVictor Margelidon-Cozzolino, Sophie Hodin, Elodie Jacqueroux, Olivier Delézay, Laurent Bertoletti and Xavier DelavenneJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 519-525; DOI: https://doi.org/10.1124/jpet.117.245993
Jansson, Paul
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
Jennis, Matthew
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Jeong, Ji Hoon
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Jesudason, Cynthia
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Jiao, Hai-Xia
- You have accessTransient Receptor Potential Melastatin-8 Activation Induces Relaxation of Pulmonary Artery by Inhibition of Store-Operated Calcium Entry in Normoxic and Chronic Hypoxic Pulmonary Hypertensive RatsYun-Ping Mu, Da-Cen Lin, Si-Yi Zheng, Hai-Xia Jiao, James S. K. Sham and Mo-Jun LinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 544-555; DOI: https://doi.org/10.1124/jpet.117.247320
Jilek, Joseph L.
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Johnson, Megan
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Johnson, Michael P.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Jung, Tae Woo
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
K
Kai, Kiyonori
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Katus, Hugo A.
- You have accessNew Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) ChannelsConstanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk ThomasJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 614-623; DOI: https://doi.org/10.1124/jpet.118.247692
Kearns, Jamie
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Kennedy, Matthew E.
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Kim, Hyoung-Chun
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Kirchner, Thomas
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Kitano, Yutaka
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Kleijn, Huub Jan
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Kodani, Sean D.
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Kosa, Rachel E.
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Kubo, Michiaki
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Kuduk, Scott D.
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Kuo, Gee-Hong
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Kyung, Eun Jung
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
L
Labbe, Gilles
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Lang, Wensheng
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Lange, Henry S.
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Lara, Primo N.
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Lee, Sung Hoon
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Le Guillou, Dounia
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Lenhard, James
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Li, Hu
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Li, Xi
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Liang, Yin
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Lin, Da-Cen
- You have accessTransient Receptor Potential Melastatin-8 Activation Induces Relaxation of Pulmonary Artery by Inhibition of Store-Operated Calcium Entry in Normoxic and Chronic Hypoxic Pulmonary Hypertensive RatsYun-Ping Mu, Da-Cen Lin, Si-Yi Zheng, Hai-Xia Jiao, James S. K. Sham and Mo-Jun LinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 544-555; DOI: https://doi.org/10.1124/jpet.117.247320
Lin, Mo-Jun
- You have accessTransient Receptor Potential Melastatin-8 Activation Induces Relaxation of Pulmonary Artery by Inhibition of Store-Operated Calcium Entry in Normoxic and Chronic Hypoxic Pulmonary Hypertensive RatsYun-Ping Mu, Da-Cen Lin, Si-Yi Zheng, Hai-Xia Jiao, James S. K. Sham and Mo-Jun LinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 544-555; DOI: https://doi.org/10.1124/jpet.117.247320
Liu, Guang
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Liu, Yani
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Liu, Zhiqiang
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Lombès, Anne
- You have accessDrug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG CellsDounia Le Guillou, Simon Bucher, Karima Begriche, Delphine Hoët, Anne Lombès, Gilles Labbe and Bernard FromentyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 711-726; DOI: https://doi.org/10.1124/jpet.117.246751
Long, Kim
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Lummertz da Rocha, Edroaldo
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Lundin, Sofia
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
M
Mager, Donald E.
- You have accessNetwork-Based Analysis of Bortezomib Pharmacodynamic Heterogeneity in Multiple Myeloma CellsVidya Ramakrishnan and Donald E. MagerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 734-751; DOI: https://doi.org/10.1124/jpet.118.247924
Mahon, Chantal
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Margelidon-Cozzolino, Victor
- You have accessIn Vitro Assessment of Pharmacokinetic Drug-Drug Interactions of Direct Oral Anticoagulants: Type 5-Phosphodiesterase Inhibitors Are Inhibitors of Rivaroxaban and Apixaban Efflux by P-GlycoproteinVictor Margelidon-Cozzolino, Sophie Hodin, Elodie Jacqueroux, Olivier Delézay, Laurent Bertoletti and Xavier DelavenneJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 519-525; DOI: https://doi.org/10.1124/jpet.117.245993
Masferrer, Jaime L.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Matsuda, Fumihiko
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Meoli, David F.
- You have accessInhibition of the α-Subunit of Phosphoinositide 3-Kinase in Heart Increases Late Sodium Current and Is ArrhythmogenicTao Yang, David F. Meoli, Javid Moslehi and Dan M. RodenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 460-466; DOI: https://doi.org/10.1124/jpet.117.246157
Michener, Maria S.
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Mikkelsen, Ross B.
- You have accessSepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular NormalizationChristopher S. Rabender, Ninu Bruno, Asim Alam, Gobalakrishnan Sundaresan, Jamal Zweit and Ross B. MikkelsenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 536-543; DOI: https://doi.org/10.1124/jpet.117.245258
Milne, G. Todd
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Min, Chris
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Miyashiro, Joy
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Modi, Sweta
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Mogg, Adrian J.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Moore, Joel D.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Morisseau, Christophe
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Morrison, Keith
- Open AccessSelective Prostacyclin Receptor Agonist Selexipag, in Contrast to Prostacyclin Analogs, Does Not Evoke Paradoxical Vasoconstriction of the Rat Femoral ArteryKeith Morrison, Franck Haag, Roland Ernst, Marc Iglarz and Martine ClozelJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 727-733; DOI: https://doi.org/10.1124/jpet.117.246058
Moslehi, Javid
- You have accessInhibition of the α-Subunit of Phosphoinositide 3-Kinase in Heart Increases Late Sodium Current and Is ArrhythmogenicTao Yang, David F. Meoli, Javid Moslehi and Dan M. RodenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 460-466; DOI: https://doi.org/10.1124/jpet.117.246157
Mostoller, Kate
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Mu, Yun-Ping
- You have accessTransient Receptor Potential Melastatin-8 Activation Induces Relaxation of Pulmonary Artery by Inhibition of Store-Operated Calcium Entry in Normoxic and Chronic Hypoxic Pulmonary Hypertensive RatsYun-Ping Mu, Da-Cen Lin, Si-Yi Zheng, Hai-Xia Jiao, James S. K. Sham and Mo-Jun LinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 544-555; DOI: https://doi.org/10.1124/jpet.117.247320
P
Pajkovic, Natasa
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Park, Eon Sub
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Patel, Naimish
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
Pehrson, Rikard
- You have accessAZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic ExposureRikard Pehrson, Tove Hegelund-Myrbäck, Danen Cunoosamy, Sara Asimus, Paul Jansson, Naimish Patel, Annika Borde and Sofia LundinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 567-572; DOI: https://doi.org/10.1124/jpet.117.246132
Petrosino, Stefania
- You have accessAnti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact DermatitisStefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone and Vincenzo Di MarzoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI: https://doi.org/10.1124/jpet.117.244368
Polidori, David
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Popichak, Katriana A.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Profy, Albert T.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Q
Qiu, Jing-Xin
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Qiu, Yinli
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
R
Rabender, Christopher S.
- You have accessSepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular NormalizationChristopher S. Rabender, Ninu Bruno, Asim Alam, Gobalakrishnan Sundaresan, Jamal Zweit and Ross B. MikkelsenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 536-543; DOI: https://doi.org/10.1124/jpet.117.245258
Ramakrishnan, Vidya
- You have accessNetwork-Based Analysis of Bortezomib Pharmacodynamic Heterogeneity in Multiple Myeloma CellsVidya Ramakrishnan and Donald E. MagerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 734-751; DOI: https://doi.org/10.1124/jpet.118.247924
Ranganath, Sheila
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Ratte, Antonius
- You have accessNew Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) ChannelsConstanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk ThomasJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 614-623; DOI: https://doi.org/10.1124/jpet.118.247692
Reddy, Doodipala Samba
- You have access3β-Methyl-Neurosteroid Analogs Are Preferential Positive Allosteric Modulators and Direct Activators of Extrasynaptic δ-Subunit γ-Aminobutyric Acid Type A Receptors in the Hippocampus Dentate Gyrus SubfieldShu-Hui Chuang and Doodipala Samba ReddyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 583-601; DOI: https://doi.org/10.1124/jpet.117.246660
Ren, Shu-Ting
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Richman, Evan H.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Roden, Dan M.
- You have accessInhibition of the α-Subunit of Phosphoinositide 3-Kinase in Heart Increases Late Sodium Current and Is ArrhythmogenicTao Yang, David F. Meoli, Javid Moslehi and Dan M. RodenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 460-466; DOI: https://doi.org/10.1124/jpet.117.246157
Rodrigues, A. David
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
S
Safe, Stephen
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Sanger, Helen E.
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Sarno, Renee
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Savage, Mary J.
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Schmidt, Constanze
- You have accessNew Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) ChannelsConstanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk ThomasJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 614-623; DOI: https://doi.org/10.1124/jpet.118.247692
Schober, Douglas
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Scott, Sheyenne
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Sham, James S. K.
- You have accessTransient Receptor Potential Melastatin-8 Activation Induces Relaxation of Pulmonary Artery by Inhibition of Store-Operated Calcium Entry in Normoxic and Chronic Hypoxic Pulmonary Hypertensive RatsYun-Ping Mu, Da-Cen Lin, Si-Yi Zheng, Hai-Xia Jiao, James S. K. Sham and Mo-Jun LinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 544-555; DOI: https://doi.org/10.1124/jpet.117.247320
Shea, Courtney
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Shepherd, Lois E.
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Sheppeck, James
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Shin, Yong Kyu
- You have accessProtectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 ExpressionTae Woo Jung, Eun Jung Kyung, Hyoung-Chun Kim, Yong Kyu Shin, Sung Hoon Lee, Eon Sub Park, Ahmet Hacımüftüoğlu, A. M. Abd El-Aty and Ji Hoon JeongJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 485-493; DOI: https://doi.org/10.1124/jpet.117.246686
Si, Ruo-Yan
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Smith, Alex
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Stone, Julie
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Sun, Peng-Fei
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Sun, Xiaocun
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Sundaresan, Gobalakrishnan
- You have accessSepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular NormalizationChristopher S. Rabender, Ninu Bruno, Asim Alam, Gobalakrishnan Sundaresan, Jamal Zweit and Ross B. MikkelsenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 536-543; DOI: https://doi.org/10.1124/jpet.117.245258
Sykes, Kristine
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
T
Takahashi, Makoto
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Tang, Kim
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Thomas, Dierk
- You have accessNew Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) ChannelsConstanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk ThomasJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 614-623; DOI: https://doi.org/10.1124/jpet.118.247692
Tian, Tian
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Tjalkens, Ronald B.
- Open AccessThe Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced ParkinsonismSean L. Hammond, Katriana A. Popichak, Xi Li, Lindsay G. Hunt, Evan H. Richman, Pranav U. Damale, Edwin K. P. Chong, Donald S. Backos, Stephen Safe and Ronald B. TjalkensJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 636-651; DOI: https://doi.org/10.1124/jpet.117.246389
Tobin, Jenny V.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Townsend, Logan K.
- You have accessAICAR Prevents Acute Olanzapine-Induced Disturbances in Glucose HomeostasisNatasha D. Bush, Logan K. Townsend and David C. WrightJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 526-535; DOI: https://doi.org/10.1124/jpet.118.248393
Tremaine, Larry M.
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Tu, Mei-Juan
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
U
Ufuk, Ayşe
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Uslaner, Jason M.
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
V
Vaia, Massimo
- You have accessAnti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact DermatitisStefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone and Vincenzo Di MarzoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI: https://doi.org/10.1124/jpet.117.244368
van Maanen, Eline M. T.
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
van Steeg, Tamara J.
- You have accessExtending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M. T. van Maanen, Tamara J. van Steeg, Maurice J. Ahsman, Maria S. Michener, Mary J. Savage, Matthew E. Kennedy, Huub Jan Kleijn, Julie Stone and Meindert DanhofJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 507-518; DOI: https://doi.org/10.1124/jpet.117.244699
Varma, Manthena V. S.
- You have accessIn Vitro–In Vivo Extrapolation of OATP1B-Mediated Drug–Drug Interactions in Cynomolgus MonkeyAyşe Ufuk, Rachel E. Kosa, Hongying Gao, Yi-An Bi, Sweta Modi, Dana Gates, A. David Rodrigues, Larry M. Tremaine, Manthena V. S. Varma, J. Brian Houston and Aleksandra GaletinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 688-699; DOI: https://doi.org/10.1124/jpet.118.247767
Verde, Roberta
- You have accessAnti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact DermatitisStefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone and Vincenzo Di MarzoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 652-663; DOI: https://doi.org/10.1124/jpet.117.244368
W
Wakefield, James
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Wallace, Nathanial
- Open AccessPotent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in RodentsFuyong Du, Simon A. Hinke, Cassandre Cavanaugh, David Polidori, Nathanial Wallace, Thomas Kirchner, Matthew Jennis, Wensheng Lang, Gee-Hong Kuo, Micheal D. Gaul, James Lenhard, Keith Demarest, Nadim J. Ajami, Yin Liang and Pamela J. HornbyJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 676-687; DOI: https://doi.org/10.1124/jpet.118.248575
Wang, Bing
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Wang, KeWei
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Wang, Liewei
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Wang, Shu
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Warrington, Steve
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Wei, Yaqin
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Weinshilboum, Richard M.
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Wiedmann, Felix
- You have accessNew Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) ChannelsConstanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk ThomasJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 614-623; DOI: https://doi.org/10.1124/jpet.118.247692
Wittmann, Marion
- You have accessPreclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622Jason M. Uslaner, Scott D. Kuduk, Marion Wittmann, Henry S. Lange, Steve V. Fox, Chris Min, Natasa Pajkovic, Dawn Harris, Caroline Cilissen, Chantal Mahon, Kate Mostoller, Steve Warrington and Douglas C. BeshoreJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 556-566; DOI: https://doi.org/10.1124/jpet.117.245894
Wright, David C.
- You have accessAICAR Prevents Acute Olanzapine-Induced Disturbances in Glucose HomeostasisNatasha D. Bush, Logan K. Townsend and David C. WrightJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 526-535; DOI: https://doi.org/10.1124/jpet.118.248393
Wright, Rebecca
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Wu, Dayong
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Wun, Theodore
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
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Xiao, Hongling
- You have accessIn Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J. Mogg, Thomas Eessalu, Megan Johnson, Rebecca Wright, Helen E. Sanger, Hongling Xiao, Michael G. Crabtree, Alex Smith, Ellen M. Colvin, Douglas Schober, Donald Gehlert, Cynthia Jesudason, Paul J. Goldsmith, Michael P. Johnson, Christian C. Felder, Vanessa N. Barth and Lisa M. BroadJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 602-613; DOI: https://doi.org/10.1124/jpet.117.246454
Xiao, Ting
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Xu, Shan-Shan
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Xu, Xiangqing
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Y
Yamamura, Naotoshi
- Open AccessBinding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium ChannelsYuki Domon, Naohisa Arakawa, Tatsuya Inoue, Fumihiko Matsuda, Makoto Takahashi, Naotoshi Yamamura, Kiyonori Kai and Yutaka KitanoJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 573-582; DOI: https://doi.org/10.1124/jpet.117.247551
Yang, Tao
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Yu, Ai-Ming
- You have accessBioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyPui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L. Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N. Lara, Ralph W. DeVere White, Hong-Wu Chen and Ai-Ming YuJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 494-506; DOI: https://doi.org/10.1124/jpet.118.247775
Z
Zhang, Cheng
- You have accessTCL1A, a Novel Transcription Factor and a Coregulator of Nuclear Factor κB p65: Single Nucleotide Polymorphism and Estrogen DependenceMing-Fen Ho, Edroaldo Lummertz da Rocha, Cheng Zhang, James N. Ingle, Paul E. Goss, Lois E. Shepherd, Michiaki Kubo, Liewei Wang, Hu Li and Richard M. WeinshilboumJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 700-710; DOI: https://doi.org/10.1124/jpet.118.247718
Zhang, Guisen
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Zhang, Jian
- You have accessUltrasound Combined with Microbubbles Enhances the Effects of Methylprednisolone in Lipopolysaccharide-Induced Human Mesangial CellsPeng-Fei Sun, Tian Tian, Li-Na Chen, Rong-Guo Fu, Shan-Shan Xu, Hong Ai, Bing Wang, Jian Zhang, Ruo-Yan Si, Zhonglin Chai, Mark E. Cooper and Shu-Ting RenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 476-484; DOI: https://doi.org/10.1124/jpet.117.246223
Zhao, Ling
- You have accessIndomethacin Enhances Brown Fat ActivityLei Hao, Jamie Kearns, Sheyenne Scott, Dayong Wu, Sean D. Kodani, Christophe Morisseau, Bruce D. Hammock, Xiaocun Sun, Ling Zhao and Shu WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 467-475; DOI: https://doi.org/10.1124/jpet.117.246256
Zhao, Song
- You have accessPharmacological Characterization of H05, a Novel Serotonin and Noradrenaline Reuptake Inhibitor with Moderate 5-HT2A Antagonist Activity for the Treatment of DepressionXiangqing Xu, Yaqin Wei, Qiang Guo, Song Zhao, Zhiqiang Liu, Ting Xiao, Yani Liu, Yinli Qiu, Yuanyuan Hou, Guisen Zhang and KeWei WangJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 624-635; DOI: https://doi.org/10.1124/jpet.118.248351
Zheng, Si-Yi
- You have accessTransient Receptor Potential Melastatin-8 Activation Induces Relaxation of Pulmonary Artery by Inhibition of Store-Operated Calcium Entry in Normoxic and Chronic Hypoxic Pulmonary Hypertensive RatsYun-Ping Mu, Da-Cen Lin, Si-Yi Zheng, Hai-Xia Jiao, James S. K. Sham and Mo-Jun LinJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 544-555; DOI: https://doi.org/10.1124/jpet.117.247320
Zimmer, Daniel P.
- Open AccessPharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of DiseaseJenny V. Tobin, Daniel P. Zimmer, Courtney Shea, Peter Germano, Sylvie G. Bernier, Guang Liu, Kim Long, Joy Miyashiro, Sheila Ranganath, Sarah Jacobson, Kim Tang, G-Yoon Jamie Im, James Sheppeck, Joel D. Moore, Kristine Sykes, James Wakefield, Renee Sarno, Ali R. Banijamali, Albert T. Profy, G. Todd Milne, Mark G. Currie and Jaime L. MasferrerJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 664-675; DOI: https://doi.org/10.1124/jpet.117.247429
Zweit, Jamal
- You have accessSepiapterin Enhances Tumor Radio- and Chemosensitivities by Promoting Vascular NormalizationChristopher S. Rabender, Ninu Bruno, Asim Alam, Gobalakrishnan Sundaresan, Jamal Zweit and Ross B. MikkelsenJournal of Pharmacology and Experimental Therapeutics June 2018, 365 (3) 536-543; DOI: https://doi.org/10.1124/jpet.117.245258
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