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Index by author

April 01, 2018; Volume 365,Issue 1

A

  1. Addo, Samuel

    1. Role of the Pregnane X Receptor in Binge Ethanol-Induced Steatosis and Hepatotoxicity
      Sora Choi, Afua A. Gyamfi, Prince Neequaye, Samuel Addo, Frank J. Gonzalez and Maxwell A. Gyamfi
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 165-178; DOI: https://doi.org/10.1124/jpet.117.244665

  2. Alberati, Daniela

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  3. Alkhlaif, Yasmin

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

  4. Al Samri, Halima

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

B

  1. Bagdas, Deniz

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

  2. Banks, Matthew L.

    1. Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Jeremy C. Cornelissen, Samuel Obeng, Kenner C. Rice, Yan Zhang, S. Stevens Negus and Matthew L. Banks
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 37-47; DOI: https://doi.org/10.1124/jpet.117.246439

  3. Becker, Mara L.

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

  4. Behl, Berthold

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  5. Bespalov, Anton

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  6. Brodzik, Anna

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

C

  1. Cao, Yingnan

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  2. Carlisle, Samantha M.

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  3. Chen, Honglei

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  4. Chen, Xi

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  5. Choi, Sora

    1. Role of the Pregnane X Receptor in Binge Ethanol-Induced Steatosis and Hepatotoxicity
      Sora Choi, Afua A. Gyamfi, Prince Neequaye, Samuel Addo, Frank J. Gonzalez and Maxwell A. Gyamfi
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 165-178; DOI: https://doi.org/10.1124/jpet.117.244665

  6. Collins, Michael A.

    1. PARP Inhibition Prevents Ethanol-Induced Neuroinflammatory Signaling and Neurodegeneration in Rat Adult-Age Brain Slice Cultures
      Nuzhath Tajuddin, Hee-Yong Kim and Michael A. Collins
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 117-126; DOI: https://doi.org/10.1124/jpet.117.245290

  7. Cornelissen, Jeremy C.

    1. Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Jeremy C. Cornelissen, Samuel Obeng, Kenner C. Rice, Yan Zhang, S. Stevens Negus and Matthew L. Banks
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 37-47; DOI: https://doi.org/10.1124/jpet.117.246439

D

  1. Damaj, Imad M.

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

  2. Doddareddy, Rajitha

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  3. Doll, Mark A.

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  4. Donsante, Yuping

    1. Dopamine Receptor Agonist Treatment of Idiopathic Dystonia: A Reappraisal in Humans and Mice
      Xueliang Fan, Yuping Donsante, H. A. Jinnah and Ellen J. Hess
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 20-26; DOI: https://doi.org/10.1124/jpet.117.246348

E

  1. El Nebrisi, Eslam Gaber

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

F

  1. Fan, Xueliang

    1. Dopamine Receptor Agonist Treatment of Idiopathic Dystonia: A Reappraisal in Humans and Mice
      Xueliang Fan, Yuping Donsante, H. A. Jinnah and Ellen J. Hess
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 20-26; DOI: https://doi.org/10.1124/jpet.117.246348

  2. Fukuchi, Mamoru

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  3. Funk, Ryan S.

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

G

  1. Geist, Brian

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  2. Getachew, Robel

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  3. Gonzalez, Frank J.

    1. Role of the Pregnane X Receptor in Binge Ethanol-Induced Steatosis and Hepatotoxicity
      Sora Choi, Afua A. Gyamfi, Prince Neequaye, Samuel Addo, Frank J. Gonzalez and Maxwell A. Gyamfi
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 165-178; DOI: https://doi.org/10.1124/jpet.117.244665

  4. Gouda, Hiroaki

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  5. Green, Cecelia L.

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738

  6. Gyamfi, Afua A.

    1. Role of the Pregnane X Receptor in Binge Ethanol-Induced Steatosis and Hepatotoxicity
      Sora Choi, Afua A. Gyamfi, Prince Neequaye, Samuel Addo, Frank J. Gonzalez and Maxwell A. Gyamfi
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 165-178; DOI: https://doi.org/10.1124/jpet.117.244665

  7. Gyamfi, Maxwell A.

    1. Role of the Pregnane X Receptor in Binge Ethanol-Induced Steatosis and Hepatotoxicity
      Sora Choi, Afua A. Gyamfi, Prince Neequaye, Samuel Addo, Frank J. Gonzalez and Maxwell A. Gyamfi
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 165-178; DOI: https://doi.org/10.1124/jpet.117.244665

H

  1. Halder, Sebok Kumar

    1. Amlexanox Inhibits Cerebral Ischemia-Induced Delayed Astrocytic High-Mobility Group Box 1 Release and Subsequent Brain Damage
      Sebok Kumar Halder and Hiroshi Ueda
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 27-36; DOI: https://doi.org/10.1124/jpet.117.245340

  2. Hayakawa, Daichi

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  3. Hein, David W.

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  4. Heruth, Daniel P.

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

  5. Hess, Ellen J.

    1. Dopamine Receptor Agonist Treatment of Idiopathic Dystonia: A Reappraisal in Humans and Mice
      Xueliang Fan, Yuping Donsante, H. A. Jinnah and Ellen J. Hess
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 20-26; DOI: https://doi.org/10.1124/jpet.117.246348

  6. Howarth, Frank Christopher

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

  7. Hu, Dong Gui

    1. Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites
      Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu and Robyn Meech
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 48-59; DOI: https://doi.org/10.1124/jpet.117.245936

  8. Huang, Keqing

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  9. Hunt, C. Anthony

    1. A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Open Access
      A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Andrew K. Smith, Yanli Xu, Glen E. P. Ropella and C. Anthony Hunt
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 127-138; DOI: https://doi.org/10.1124/jpet.117.245019

I

  1. Imada, Haruka

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  2. Ito, Yuki

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  3. Iwashita, Hiroki

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

J

  1. Jiang, Xiling

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  2. Jinnah, H. A.

    1. Dopamine Receptor Agonist Treatment of Idiopathic Dystonia: A Reappraisal in Humans and Mice
      Xueliang Fan, Yuping Donsante, H. A. Jinnah and Ellen J. Hess
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 20-26; DOI: https://doi.org/10.1124/jpet.117.246348

  3. Jusko, William J.

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

K

  1. Kamato, Danielle

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  2. Keller, Staci N.

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738

  3. Kim, Hee-Yong

    1. PARP Inhibition Prevents Ethanol-Induced Neuroinflammatory Signaling and Neurodegeneration in Rat Adult-Age Brain Slice Cultures
      Nuzhath Tajuddin, Hee-Yong Kim and Michael A. Collins
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 117-126; DOI: https://doi.org/10.1124/jpet.117.245290

  4. Klinge, Carolyn M.

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  5. Kurihara, Takashi

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

L

  1. Leeder, J. Steven

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

  2. Legakis, L. P.

    1. Repeated Morphine Produces Sensitization to Reward and Tolerance to Antiallodynia in Male and Female Rats with Chemotherapy-Induced Neuropathy
      L. P. Legakis and S. S. Negus
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 9-19; DOI: https://doi.org/10.1124/jpet.117.246215

  3. Li, Ying

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  4. Little, Peter J.

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  5. Liu, Xiaoxiao

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  6. Liu, Yanzhuo

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

M

  1. Mackenzie, Peter I.

    1. Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites
      Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu and Robyn Meech
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 48-59; DOI: https://doi.org/10.1124/jpet.117.245936

  2. Maines, Lynn W.

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738

  3. Martin, Robert C. G.

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  4. McCarthy, Cameron G.

    1. Toll-Like Receptor 9–Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells
      Cameron G. McCarthy, Camilla F. Wenceslau, Safia Ogbi, Theodora Szasz and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 60-71; DOI: https://doi.org/10.1124/jpet.117.245746

  5. McIntosh, Thomas

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  6. McKinnon, Ross A.

    1. Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites
      Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu and Robyn Meech
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 48-59; DOI: https://doi.org/10.1124/jpet.117.245936

  7. Meech, Robyn

    1. Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites
      Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu and Robyn Meech
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 48-59; DOI: https://doi.org/10.1124/jpet.117.245936

  8. Mitra, Partha

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  9. Miyamoto, Maki

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  10. Miyata, Atsuro

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

N

  1. Nagashima, Ryota

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  2. Nakashima, Masato

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  3. Neequaye, Prince

    1. Role of the Pregnane X Receptor in Binge Ethanol-Induced Steatosis and Hepatotoxicity
      Sora Choi, Afua A. Gyamfi, Prince Neequaye, Samuel Addo, Frank J. Gonzalez and Maxwell A. Gyamfi
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 165-178; DOI: https://doi.org/10.1124/jpet.117.244665

  4. Negus, S. S.

    1. Repeated Morphine Produces Sensitization to Reward and Tolerance to Antiallodynia in Male and Female Rats with Chemotherapy-Induced Neuropathy
      L. P. Legakis and S. S. Negus
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 9-19; DOI: https://doi.org/10.1124/jpet.117.246215

  5. Negus, S. Stevens

    1. Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Jeremy C. Cornelissen, Samuel Obeng, Kenner C. Rice, Yan Zhang, S. Stevens Negus and Matthew L. Banks
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 37-47; DOI: https://doi.org/10.1124/jpet.117.246439

O

  1. Obeng, Samuel

    1. Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Jeremy C. Cornelissen, Samuel Obeng, Kenner C. Rice, Yan Zhang, S. Stevens Negus and Matthew L. Banks
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 37-47; DOI: https://doi.org/10.1124/jpet.117.246439

  2. Ogbi, Safia

    1. Toll-Like Receptor 9–Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells
      Cameron G. McCarthy, Camilla F. Wenceslau, Safia Ogbi, Theodora Szasz and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 60-71; DOI: https://doi.org/10.1124/jpet.117.245746

  3. Okada, Takuya

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  4. Osman, Narin

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  5. Oz, Murat

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

P

  1. Piva, Terrence J.

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

Q

  1. Qiu, Miao

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

R

  1. Rice, Kenner C.

    1. Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Jeremy C. Cornelissen, Samuel Obeng, Kenner C. Rice, Yan Zhang, S. Stevens Negus and Matthew L. Banks
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 37-47; DOI: https://doi.org/10.1124/jpet.117.246439

  2. Ropella, Glen E. P.

    1. A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Open Access
      A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Andrew K. Smith, Yanli Xu, Glen E. P. Ropella and C. Anthony Hunt
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 127-138; DOI: https://doi.org/10.1124/jpet.117.245019

  3. Roßmanith, Martin

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  4. Rostam, Muhamad A.

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

S

  1. Schrecengost, Randy S.

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738

  2. Shajimoon, Aravindra

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  3. Shiraishi, Eri

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  4. Singh, Rakesh K.

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

  5. Smith, Andrew K.

    1. A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Open Access
      A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Andrew K. Smith, Yanli Xu, Glen E. P. Ropella and C. Anthony Hunt
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 127-138; DOI: https://doi.org/10.1124/jpet.117.245019

  6. Smith, Charles D.

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738

  7. Smith, Ryan A.

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738

  8. Spanagel, Rainer

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  9. States, J. Christopher

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  10. Suzuki, Noriko

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  11. Szasz, Theodora

    1. Toll-Like Receptor 9–Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells
      Cameron G. McCarthy, Camilla F. Wenceslau, Safia Ogbi, Theodora Szasz and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 60-71; DOI: https://doi.org/10.1124/jpet.117.245746

T

  1. Tajuddin, Nuzhath

    1. PARP Inhibition Prevents Ethanol-Induced Neuroinflammatory Signaling and Neurodegeneration in Rat Adult-Age Brain Slice Cultures
      Nuzhath Tajuddin, Hee-Yong Kim and Michael A. Collins
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 117-126; DOI: https://doi.org/10.1124/jpet.117.245290

  2. Takahashi, Tatiane T.

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  3. Takasaki, Ichiro

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  4. Taniguchi, Takahiko

    1. Phosphodiesterase 2A Inhibitor TAK-915 Ameliorates Cognitive Impairments and Social Withdrawal in N-Methyl-d-Aspartate Receptor Antagonist–Induced Rat Models of Schizophrenia
      Masato Nakashima, Haruka Imada, Eri Shiraishi, Yuki Ito, Noriko Suzuki, Maki Miyamoto, Takahiko Taniguchi and Hiroki Iwashita
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 179-188; DOI: https://doi.org/10.1124/jpet.117.245506

  5. Toma, Wisam

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

  6. Toyooka, Naoki

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

U

  1. Ueda, Hiroshi

    1. Amlexanox Inhibits Cerebral Ischemia-Induced Delayed Astrocytic High-Mobility Group Box 1 Release and Subsequent Brain Damage
      Sebok Kumar Halder and Hiroshi Ueda
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 27-36; DOI: https://doi.org/10.1124/jpet.117.245340

V

  1. van Haandel, Leon

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

  2. Vengeliene, Valentina

    1. Targeting Glycine Reuptake in Alcohol Seeking and Relapse
      Valentina Vengeliene, Martin Roßmanith, Tatiane T. Takahashi, Daniela Alberati, Berthold Behl, Anton Bespalov and Rainer Spanagel
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 202-211; DOI: https://doi.org/10.1124/jpet.117.244822

  3. Vore, Mary

    1. Publishing in an ASPET Journal – What’s in It for You?
      Mary Vore
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 94-95; DOI: https://doi.org/10.1124/jpet.117.248534

W

  1. Wang, Chenlong

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  2. Wang, Weirong

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  3. Watanabe, Ai

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  4. Watanabe, Yurie

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

  5. Webb, R. Clinton

    1. Toll-Like Receptor 9–Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells
      Cameron G. McCarthy, Camilla F. Wenceslau, Safia Ogbi, Theodora Szasz and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 60-71; DOI: https://doi.org/10.1124/jpet.117.245746

  6. Wenceslau, Camilla F.

    1. Toll-Like Receptor 9–Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells
      Cameron G. McCarthy, Camilla F. Wenceslau, Safia Ogbi, Theodora Szasz and R. Clinton Webb
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 60-71; DOI: https://doi.org/10.1124/jpet.117.245746

  7. Wijayakumara, Dhilushi D.

    1. Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites
      Dhilushi D. Wijayakumara, Peter I. Mackenzie, Ross A. McKinnon, Dong Gui Hu and Robyn Meech
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 48-59; DOI: https://doi.org/10.1124/jpet.117.245936

X

  1. Xu, Yanli

    1. A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Open Access
      A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation
      Andrew K. Smith, Yanli Xu, Glen E. P. Ropella and C. Anthony Hunt
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 127-138; DOI: https://doi.org/10.1124/jpet.117.245019

Y

  1. Yang, Jing

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  2. Yang, Keun-Hang Susan

    1. Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
      Eslam Gaber El Nebrisi, Deniz Bagdas, Wisam Toma, Halima Al Samri, Anna Brodzik, Yasmin Alkhlaif, Keun-Hang Susan Yang, Frank Christopher Howarth, Imad M. Damaj and Murat Oz
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 190-200; DOI: https://doi.org/10.1124/jpet.117.245068

  3. Yang, Yuqing

    1. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis
      Chenlong Wang, Ying Li, Honglei Chen, Keqing Huang, Xiaoxiao Liu, Miao Qiu, Yanzhuo Liu, Yuqing Yang and Jing Yang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 72-83; DOI: https://doi.org/10.1124/jpet.117.247130

  4. Ye, Shui Q.

    1. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP
      Rakesh K. Singh, Leon van Haandel, Daniel P. Heruth, Shui Q. Ye, J. Steven Leeder, Mara L. Becker and Ryan S. Funk
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 96-106; DOI: https://doi.org/10.1124/jpet.117.246199

  5. Yokai, Masafumi

    1. In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor
      Ichiro Takasaki, Ai Watanabe, Masafumi Yokai, Yurie Watanabe, Daichi Hayakawa, Ryota Nagashima, Mamoru Fukuchi, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Hiroaki Gouda and Takashi Kurihara
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 1-8; DOI: https://doi.org/10.1124/jpet.117.245415

Z

  1. Zhang, Xiaoyan

    1. High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5<em>α</em>-androstane-3<em>β</em>, 17<em>β</em>-Diol, or Dihydrotestosterone in Breast Cancer Cells
      High N-Acetyltransferase 1 Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 5α-androstane-3β, 17β-Diol, or Dihydrotestosterone in Breast Cancer Cells
      Xiaoyan Zhang, Samantha M. Carlisle, Mark A. Doll, Robert C. G. Martin, J. Christopher States, Carolyn M. Klinge and David W. Hein
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 84-93; DOI: https://doi.org/10.1124/jpet.117.247031

  2. Zhang, Yan

    1. Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys
      Jeremy C. Cornelissen, Samuel Obeng, Kenner C. Rice, Yan Zhang, S. Stevens Negus and Matthew L. Banks
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 37-47; DOI: https://doi.org/10.1124/jpet.117.246439

  3. Zheng, Wenhua

    1. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2
      Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman and Peter J. Little
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 156-164; DOI: https://doi.org/10.1124/jpet.117.244483

  4. Zhou, Honghui

    1. Open Access
      Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice
      Xi Chen, Xiling Jiang, Rajitha Doddareddy, Brian Geist, Thomas McIntosh, William J. Jusko, Honghui Zhou and Weirong Wang
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 140-155; DOI: https://doi.org/10.1124/jpet.117.244855

  5. Zhuang, Yan

    1. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183
      Randy S. Schrecengost, Cecelia L. Green, Yan Zhuang, Staci N. Keller, Ryan A. Smith, Lynn W. Maines and Charles D. Smith
      Journal of Pharmacology and Experimental Therapeutics April 2018, 365 (1) 107-116; DOI: https://doi.org/10.1124/jpet.117.245738
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