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  • Other Publications
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Journal of Pharmacology and Experimental Therapeutics

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  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

August 01, 2017; Volume 362,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abe, Takaaki

    1. You have access
      Potential Drug Interactions Mediated by Renal Organic Anion Transporter OATP4C1
      Toshihiro Sato, Eikan Mishima, Nariyasu Mano, Takaaki Abe and Hiroaki Yamaguchi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 271-277; DOI: https://doi.org/10.1124/jpet.117.241703
  2. Allen, Stephanie C.

    1. You have access
      Pleiotropic and Adverse Effects of Statins—Do Epigenetics Play a Role?
      Stephanie C. Allen and Cyril D.S. Mamotte
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 319-326; DOI: https://doi.org/10.1124/jpet.117.242081
  3. Aponte, Angel

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  4. Arai, Tohru

    1. In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Open Access
      In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422
  5. Aslanian, Ara M.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497

B

  1. Beuckmann, Carsten Theodor

    1. In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Open Access
      In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422
  2. Bollag, Wendy B.

    1. You have access
      Anti-Psoriatic Drug Monomethylfumarate Increases Nuclear Factor Erythroid 2-Related Factor 2 Levels and Induces Aquaporin-3 mRNA and Protein Expression
      Inas Helwa, Vivek Choudhary, Xunsheng Chen, Ismail Kaddour-Djebbar and Wendy B. Bollag
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 243-253; DOI: https://doi.org/10.1124/jpet.116.239715
  3. Braman, Virginia

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497
  4. Bridson, Gary W.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497
  5. Broadley, Kenneth J.

    1. Open Access
      Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
      Alexander P. P. Lowe, Rhian S. Thomas, Anthony T. Nials, Emma J. Kidd, Kenneth J. Broadley and William R. Ford
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 327-337; DOI: https://doi.org/10.1124/jpet.117.241927
  6. Brummel, Christopher L.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497
  7. Burman, Miriam

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  8. Busch-Petersen, Jakob

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705

C

  1. Calabresi, Laura

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  2. Carey, Lawrence M.

    1. You have access
      Cannabinoid CB2 Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB1 Mechanism that is Independent of CB2 Receptors in Mice
      Ai-Ling Li, Lawrence M. Carey, Ken Mackie and Andrea G. Hohmann
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 296-305; DOI: https://doi.org/10.1124/jpet.117.241901
  3. Carpenter, Donald C.

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  4. Carr, Richard

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117
  5. Chello, Massimo

    1. You have access
      Modeling Human Myocardium Exposure to Doxorubicin Defines the Risk of Heart Failure from Low-Dose Doxorubicin
      Emanuela Salvatorelli, Pierantonio Menna, Massimo Chello, Elvio Covino and Giorgio Minotti
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 263-270; DOI: https://doi.org/10.1124/jpet.117.242388
  6. Chen, Chen

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  7. Chen, Wei

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  8. Chen, Xunsheng

    1. You have access
      Anti-Psoriatic Drug Monomethylfumarate Increases Nuclear Factor Erythroid 2-Related Factor 2 Levels and Induces Aquaporin-3 mRNA and Protein Expression
      Inas Helwa, Vivek Choudhary, Xunsheng Chen, Ismail Kaddour-Djebbar and Wendy B. Bollag
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 243-253; DOI: https://doi.org/10.1124/jpet.116.239715
  9. Choudhary, Vivek

    1. You have access
      Anti-Psoriatic Drug Monomethylfumarate Increases Nuclear Factor Erythroid 2-Related Factor 2 Levels and Induces Aquaporin-3 mRNA and Protein Expression
      Inas Helwa, Vivek Choudhary, Xunsheng Chen, Ismail Kaddour-Djebbar and Wendy B. Bollag
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 243-253; DOI: https://doi.org/10.1124/jpet.116.239715
  10. Covino, Elvio

    1. You have access
      Modeling Human Myocardium Exposure to Doxorubicin Defines the Risk of Heart Failure from Low-Dose Doxorubicin
      Emanuela Salvatorelli, Pierantonio Menna, Massimo Chello, Elvio Covino and Giorgio Minotti
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 263-270; DOI: https://doi.org/10.1124/jpet.117.242388
  11. Cowan, Conrad L.

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117
  12. Crombie, Aimee L.

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117

D

  1. Demosky, Stephen J.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457

F

  1. Foley, James

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  2. Ford, William R.

    1. Open Access
      Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
      Alexander P. P. Lowe, Rhian S. Thomas, Anthony T. Nials, Emma J. Kidd, Kenneth J. Broadley and William R. Ford
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 327-337; DOI: https://doi.org/10.1124/jpet.117.241927
  3. Freeman, Lita A.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457

G

  1. Gordon, Scott M.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  2. Gowen-MacDonald, William

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117
  3. Gucek, Marjan

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  4. Guo, Lei

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986

H

  1. Harbeson, Scott L.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497
  2. Helwa, Inas

    1. You have access
      Anti-Psoriatic Drug Monomethylfumarate Increases Nuclear Factor Erythroid 2-Related Factor 2 Levels and Induces Aquaporin-3 mRNA and Protein Expression
      Inas Helwa, Vivek Choudhary, Xunsheng Chen, Ismail Kaddour-Djebbar and Wendy B. Bollag
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 243-253; DOI: https://doi.org/10.1124/jpet.116.239715
  3. Henrich, Andrea

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  4. Higashiyama, Hiroyuki

    1. In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Open Access
      In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422
  5. Hohmann, Andrea G.

    1. You have access
      Cannabinoid CB2 Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB1 Mechanism that is Independent of CB2 Receptors in Mice
      Ai-Ling Li, Lawrence M. Carey, Ken Mackie and Andrea G. Hohmann
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 296-305; DOI: https://doi.org/10.1124/jpet.117.241901
  6. Hruba, Lenka

    1. You have access
      Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys
      Lenka Hruba and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 278-286; DOI: https://doi.org/10.1124/jpet.117.240572
  7. Huisinga, Wilhelm

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  8. Hunsberger, Gerald E.

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705

J

  1. Jadhav, Ajit

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  2. Jaehde, Ulrich

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  3. Joerger, Markus

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  4. Ju, Rui

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986

K

  1. Kaddour-Djebbar, Ismail

    1. You have access
      Anti-Psoriatic Drug Monomethylfumarate Increases Nuclear Factor Erythroid 2-Related Factor 2 Levels and Induces Aquaporin-3 mRNA and Protein Expression
      Inas Helwa, Vivek Choudhary, Xunsheng Chen, Ismail Kaddour-Djebbar and Wendy B. Bollag
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 243-253; DOI: https://doi.org/10.1124/jpet.116.239715
  2. Kidd, Emma J.

    1. Open Access
      Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
      Alexander P. P. Lowe, Rhian S. Thomas, Anthony T. Nials, Emma J. Kidd, Kenneth J. Broadley and William R. Ford
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 327-337; DOI: https://doi.org/10.1124/jpet.117.241927
  3. Kilian, David J.

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  4. Kloft, Charlotte

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  5. Koblish, Michael

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117
  6. Koby, Ross F.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  7. Konaklieva, Monika

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  8. Kraff, Stefanie

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  9. Kuskovsky, Rostislav

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457

L

  1. Lark, Michael W.

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117
  2. Levi, Roberto

    1. S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      You have access
      S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      Alice Marino, Takuya Sakamoto, Pablo A. Robador, Kengo Tomita and Roberto Levi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 230-242; DOI: https://doi.org/10.1124/jpet.117.241976
  3. Levine, Rodney L.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  4. Li, Ai-Ling

    1. You have access
      Cannabinoid CB2 Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB1 Mechanism that is Independent of CB2 Receptors in Mice
      Ai-Ling Li, Lawrence M. Carey, Ken Mackie and Andrea G. Hohmann
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 296-305; DOI: https://doi.org/10.1124/jpet.117.241901
  5. Li, Juan

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  6. Liu, Julie F.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497
  7. Lowe, Alexander P. P.

    1. Open Access
      Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
      Alexander P. P. Lowe, Rhian S. Thomas, Anthony T. Nials, Emma J. Kidd, Kenneth J. Broadley and William R. Ford
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 327-337; DOI: https://doi.org/10.1124/jpet.117.241927

M

  1. Mackie, Ken

    1. You have access
      Cannabinoid CB2 Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB1 Mechanism that is Independent of CB2 Receptors in Mice
      Ai-Ling Li, Lawrence M. Carey, Ken Mackie and Andrea G. Hohmann
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 296-305; DOI: https://doi.org/10.1124/jpet.117.241901
  2. Mamotte, Cyril D.S.

    1. You have access
      Pleiotropic and Adverse Effects of Statins—Do Epigenetics Play a Role?
      Stephanie C. Allen and Cyril D.S. Mamotte
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 319-326; DOI: https://doi.org/10.1124/jpet.117.242081
  3. Mano, Nariyasu

    1. You have access
      Potential Drug Interactions Mediated by Renal Organic Anion Transporter OATP4C1
      Toshihiro Sato, Eikan Mishima, Nariyasu Mano, Takaaki Abe and Hiroaki Yamaguchi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 271-277; DOI: https://doi.org/10.1124/jpet.117.241703
  4. Manthei, Kelly A.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  5. Marino, Alice

    1. S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      You have access
      S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      Alice Marino, Takuya Sakamoto, Pablo A. Robador, Kengo Tomita and Roberto Levi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 230-242; DOI: https://doi.org/10.1124/jpet.117.241976
  6. Mayer, Ruth J.

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  7. McMahon, Lance R.

    1. You have access
      Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys
      Lenka Hruba and Lance R. McMahon
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 278-286; DOI: https://doi.org/10.1124/jpet.117.240572
  8. Menna, Pierantonio

    1. You have access
      Modeling Human Myocardium Exposure to Doxorubicin Defines the Risk of Heart Failure from Low-Dose Doxorubicin
      Emanuela Salvatorelli, Pierantonio Menna, Massimo Chello, Elvio Covino and Giorgio Minotti
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 263-270; DOI: https://doi.org/10.1124/jpet.117.242388
  9. Minotti, Giorgio

    1. You have access
      Modeling Human Myocardium Exposure to Doxorubicin Defines the Risk of Heart Failure from Low-Dose Doxorubicin
      Emanuela Salvatorelli, Pierantonio Menna, Massimo Chello, Elvio Covino and Giorgio Minotti
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 263-270; DOI: https://doi.org/10.1124/jpet.117.242388
  10. Mishima, Eikan

    1. You have access
      Potential Drug Interactions Mediated by Renal Organic Anion Transporter OATP4C1
      Toshihiro Sato, Eikan Mishima, Nariyasu Mano, Takaaki Abe and Hiroaki Yamaguchi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 271-277; DOI: https://doi.org/10.1124/jpet.117.241703
  11. Morgan, Adam J.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497

N

  1. Nagaoka, Kazuya

    1. In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Open Access
      In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422
  2. Nguyen, Sophia

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497
  3. Nials, Anthony T.

    1. Open Access
      Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
      Alexander P. P. Lowe, Rhian S. Thomas, Anthony T. Nials, Emma J. Kidd, Kenneth J. Broadley and William R. Ford
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 327-337; DOI: https://doi.org/10.1124/jpet.117.241927

O

  1. Ossoli, Alice F.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457

P

  1. Parra-Guillen, Zinnia Patricia

    1. Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      You have access
      Semimechanistic Bone Marrow Exhaustion Pharmacokinetic/Pharmacodynamic Model for Chemotherapy-Induced Cumulative Neutropenia
      Andrea Henrich, Markus Joerger, Stefanie Kraff, Ulrich Jaehde, Wilhelm Huisinga, Charlotte Kloft and Zinnia Patricia Parra-Guillen
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 347-358; DOI: https://doi.org/10.1124/jpet.117.240309
  2. Pilja, Lana

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497

R

  1. Remaley, Alan T.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  2. Robador, Pablo A.

    1. S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      You have access
      S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      Alice Marino, Takuya Sakamoto, Pablo A. Robador, Kengo Tomita and Roberto Levi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 230-242; DOI: https://doi.org/10.1124/jpet.117.241976
  3. Rominger, David H.

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117

S

  1. Sakamoto, Takuya

    1. S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      You have access
      S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      Alice Marino, Takuya Sakamoto, Pablo A. Robador, Kengo Tomita and Roberto Levi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 230-242; DOI: https://doi.org/10.1124/jpet.117.241976
  2. Salmon, Michael

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  3. Salvatorelli, Emanuela

    1. You have access
      Modeling Human Myocardium Exposure to Doxorubicin Defines the Risk of Heart Failure from Low-Dose Doxorubicin
      Emanuela Salvatorelli, Pierantonio Menna, Massimo Chello, Elvio Covino and Giorgio Minotti
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 263-270; DOI: https://doi.org/10.1124/jpet.117.242388
  4. Sato, Toshihiro

    1. You have access
      Potential Drug Interactions Mediated by Renal Organic Anion Transporter OATP4C1
      Toshihiro Sato, Eikan Mishima, Nariyasu Mano, Takaaki Abe and Hiroaki Yamaguchi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 271-277; DOI: https://doi.org/10.1124/jpet.117.241703
  5. Shamburek, Robert D.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  6. Shen, Min

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  7. Shi, Jing

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  8. Siuda, Edward R.

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117
  9. Sun, Fangrui

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  10. Suzuki, Michiyuki

    1. In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Open Access
      In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422

T

  1. Tal-Singer, Ruth

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705
  2. Tesmer, John J.G.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  3. Thomas, Rhian S.

    1. Open Access
      Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
      Alexander P. P. Lowe, Rhian S. Thomas, Anthony T. Nials, Emma J. Kidd, Kenneth J. Broadley and William R. Ford
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 327-337; DOI: https://doi.org/10.1124/jpet.117.241927
  4. Tomita, Kengo

    1. S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      You have access
      S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2
      Alice Marino, Takuya Sakamoto, Pablo A. Robador, Kengo Tomita and Roberto Levi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 230-242; DOI: https://doi.org/10.1124/jpet.117.241976
  5. Tung, Roger D.

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497

U

  1. Ueno, Takashi

    1. In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Open Access
      In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist
      Carsten Theodor Beuckmann, Michiyuki Suzuki, Takashi Ueno, Kazuya Nagaoka, Tohru Arai and Hiroyuki Higashiyama
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 287-295; DOI: https://doi.org/10.1124/jpet.117.241422
  2. Uttamsingh, Vinita

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497

V

  1. Vaisman, Boris L.

    1. You have access
      Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
      Lita A. Freeman, Stephen J. Demosky, Monika Konaklieva, Rostislav Kuskovsky, Angel Aponte, Alice F. Ossoli, Scott M. Gordon, Ross F. Koby, Kelly A. Manthei, Min Shen, Boris L. Vaisman, Robert D. Shamburek, Ajit Jadhav, Laura Calabresi, Marjan Gucek, John J.G. Tesmer, Rodney L. Levine and Alan T. Remaley
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 306-318; DOI: https://doi.org/10.1124/jpet.117.240457
  2. Violin, Jonathan D.

    1. You have access
      TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration
      Michael Koblish, Richard Carr, Edward R. Siuda, David H. Rominger, William Gowen-MacDonald, Conrad L. Cowan, Aimee L. Crombie, Jonathan D. Violin and Michael W. Lark
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 254-262; DOI: https://doi.org/10.1124/jpet.117.241117

W

  1. Wu, Lijun

    1. Open Access
      Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
      Scott L. Harbeson, Adam J. Morgan, Julie F. Liu, Ara M. Aslanian, Sophia Nguyen, Gary W. Bridson, Christopher L. Brummel, Lijun Wu, Roger D. Tung, Lana Pilja, Virginia Braman and Vinita Uttamsingh
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 359-367; DOI: https://doi.org/10.1124/jpet.117.241497

Y

  1. Yamaguchi, Hiroaki

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      Potential Drug Interactions Mediated by Renal Organic Anion Transporter OATP4C1
      Toshihiro Sato, Eikan Mishima, Nariyasu Mano, Takaaki Abe and Hiroaki Yamaguchi
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 271-277; DOI: https://doi.org/10.1124/jpet.117.241703
  2. Ye, Caiying

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      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  3. Yonchuk, John G.

    1. Open Access
      Danirixin: A Reversible and Selective Antagonist of the CXC Chemokine Receptor 2
      Jakob Busch-Petersen, Donald C. Carpenter, Miriam Burman, James Foley, Gerald E. Hunsberger, David J. Kilian, Michael Salmon, Ruth J. Mayer, John G. Yonchuk and Ruth Tal-Singer
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 338-346; DOI: https://doi.org/10.1124/jpet.117.240705

Z

  1. Zhang, Dechang

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
  2. Zhu, Lei

    1. You have access
      Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis
      Chen Chen, Rui Ju, Jing Shi, Wei Chen, Fangrui Sun, Lei Zhu, Juan Li, Dechang Zhang, Caiying Ye and Lei Guo
      Journal of Pharmacology and Experimental Therapeutics August 2017, 362 (2) 219-229; DOI: https://doi.org/10.1124/jpet.117.240986
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Journal of Pharmacology and Experimental Therapeutics: 362 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 362, Issue 2
1 Aug 2017
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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