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Index by author

July 01, 2017; Volume 362,Issue 1

A

  1. Akamine, Eliana Hiromi

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  2. Akbarali, Hamid I.

    1. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone
      Joanna C. Jacob, Justin L. Poklis, Hamid I. Akbarali, Graeme Henderson and William L. Dewey
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 45-52; DOI: https://doi.org/10.1124/jpet.117.241083

  3. Altmann, Stephen

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  4. Andreassen, Kim V.

    1. The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes
      Sara T. Hjuler, Sofie Gydesen, Kim V. Andreassen, Morten A. Karsdal and Kim Henriksen
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 24-30; DOI: https://doi.org/10.1124/jpet.117.241281

  5. Aparecida de Oliveira, Maria

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  6. Araujo, Priscila Xavier

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

B

  1. Badiee, Mohsen

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

  2. Barrett, Andrew C.

    1. Effects of Acute and Chronic Treatments with Dopamine D2 and D3 Receptor Ligands on Cocaine versus Food Choice in Rats
      Morgane Thomsen, Andrew C. Barrett, Paul Butler, S. Stevens Negus and S. Barak Caine
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 161-176; DOI: https://doi.org/10.1124/jpet.117.241141

  3. Be, Xuhai

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  4. Becker, Ann

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  5. Berg, Kelly A.

    1. Regulation of δ Opioid Receptor-Mediated Signaling and Antinociception in Peripheral Sensory Neurons by Arachidonic Acid–Dependent 12/15-Lipoxygenase Metabolites
      Laura C. Sullivan, Teresa A. Chavera, Xiaoli Gao, Miryam M. Pando and Kelly A. Berg
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 200-209; DOI: https://doi.org/10.1124/jpet.117.241604

  6. Berry, Virginia

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  7. Böhme, Livia

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  8. Bühring, Karl-Ulrich

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  9. Butler, Paul

    1. Effects of Acute and Chronic Treatments with Dopamine D2 and D3 Receptor Ligands on Cocaine versus Food Choice in Rats
      Morgane Thomsen, Andrew C. Barrett, Paul Butler, S. Stevens Negus and S. Barak Caine
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 161-176; DOI: https://doi.org/10.1124/jpet.117.241141

C

  1. Caine, S. Barak

    1. Effects of Acute and Chronic Treatments with Dopamine D2 and D3 Receptor Ligands on Cocaine versus Food Choice in Rats
      Morgane Thomsen, Andrew C. Barrett, Paul Butler, S. Stevens Negus and S. Barak Caine
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 161-176; DOI: https://doi.org/10.1124/jpet.117.241141

  2. Carson, Kenneth G.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  3. Ceravolo, Graziela Scalianti

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  4. Chavera, Teresa A.

    1. Regulation of δ Opioid Receptor-Mediated Signaling and Antinociception in Peripheral Sensory Neurons by Arachidonic Acid–Dependent 12/15-Lipoxygenase Metabolites
      Laura C. Sullivan, Teresa A. Chavera, Xiaoli Gao, Miryam M. Pando and Kelly A. Berg
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 200-209; DOI: https://doi.org/10.1124/jpet.117.241604

  5. Chen, Jia-Jia

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  6. Cheng, Yu-Fang

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  7. Clozel, Martine

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  8. Colli, Lucas Giglio

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  9. Costa, Tiago Januário

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

D

  1. DaCosta, Christopher M.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  2. Dantas, Ana Paula

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  3. de Carvalho, Maria Helena Catelli

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  4. de Groat, William C.

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  5. Demuth, Hans-Ulrich

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  6. Dewey, William L.

    1. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone
      Joanna C. Jacob, Justin L. Poklis, Hamid I. Akbarali, Graeme Henderson and William L. Dewey
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 45-52; DOI: https://doi.org/10.1124/jpet.117.241083

  7. Dey, Asim B.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  8. Ding, Zhi-Ming

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  9. Doree, Deon D.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  10. Duddy, Steven K.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

E

  1. Echem, Cinthya

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  2. Echmalian, Corinne M.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  3. Endres, G. W.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  4. Estridge, Thomas B.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

F

  1. Farcher, Martina

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  2. Feng, Hong-Fang

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  3. France, Charles P.

    1. Preference for an Opioid/Benzodiazepine Mixture over an Opioid Alone Using a Concurrent Choice Procedure in Rhesus Monkeys
      Peter F. Weed, Charles P. France and Lisa R. Gerak
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 59-66; DOI: https://doi.org/10.1124/jpet.117.240200

  4. Freitas, Kelen C.

    1. Relief of Pain-Depressed Behavior in Rats by Activation of D1-Like Dopamine Receptors
      Matthew F. Lazenka, Kelen C. Freitas, Sydney Henck and S. Stevens Negus
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 14-23; DOI: https://doi.org/10.1124/jpet.117.240796

  5. Fremeau, Robert T.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  6. Fretland, Adrian J.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  7. Fujitsuka, Naoki

    1. Open Access
      Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
      Yumi Harada, Seiichi Iizuka, Yayoi Saegusa, Sachiko Mogami, Naoki Fujitsuka and Tomohisa Hattori
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 78-84; DOI: https://doi.org/10.1124/jpet.117.240630

G

  1. Gao, Xiaoli

    1. Regulation of δ Opioid Receptor-Mediated Signaling and Antinociception in Peripheral Sensory Neurons by Arachidonic Acid–Dependent 12/15-Lipoxygenase Metabolites
      Laura C. Sullivan, Teresa A. Chavera, Xiaoli Gao, Miryam M. Pando and Kelly A. Berg
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 200-209; DOI: https://doi.org/10.1124/jpet.117.241604

  2. Gatfield, John

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  3. Gerak, Lisa R.

    1. Preference for an Opioid/Benzodiazepine Mixture over an Opioid Alone Using a Concurrent Choice Procedure in Rhesus Monkeys
      Peter F. Weed, Charles P. France and Lisa R. Gerak
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 59-66; DOI: https://doi.org/10.1124/jpet.117.240200

  4. Gnerre, Carmela

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  5. Goodwin, Nicole C.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  6. Gopinathan, Suma

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  7. Greene, Derek L

    1. XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels that Favor Activated Single Subunits
      Derek L Greene, Seungwoo Kang and Naoto Hoshi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 177-185; DOI: https://doi.org/10.1124/jpet.117.241679

  8. Greer, Jennifer

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  9. Grim, T. W.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  10. Guo, Hai-Biao

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  11. Gydesen, Sofie

    1. The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes
      Sara T. Hjuler, Sofie Gydesen, Kim V. Andreassen, Morten A. Karsdal and Kim Henriksen
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 24-30; DOI: https://doi.org/10.1124/jpet.117.241281

H

  1. Harada, Yumi

    1. Open Access
      Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
      Yumi Harada, Seiichi Iizuka, Yayoi Saegusa, Sachiko Mogami, Naoki Fujitsuka and Tomohisa Hattori
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 78-84; DOI: https://doi.org/10.1124/jpet.117.240630

  2. Harris, Angela L.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  3. Harrison, Bryce A.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  4. Hartley, Maryalice

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  5. Hattori, Tomohisa

    1. Open Access
      Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
      Yumi Harada, Seiichi Iizuka, Yayoi Saegusa, Sachiko Mogami, Naoki Fujitsuka and Tomohisa Hattori
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 78-84; DOI: https://doi.org/10.1124/jpet.117.240630

  6. Heiser, Ulrich

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  7. Henck, Sydney

    1. Relief of Pain-Depressed Behavior in Rats by Activation of D1-Like Dopamine Receptors
      Matthew F. Lazenka, Kelen C. Freitas, Sydney Henck and S. Stevens Negus
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 14-23; DOI: https://doi.org/10.1124/jpet.117.240796

  8. Henderson, Graeme

    1. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone
      Joanna C. Jacob, Justin L. Poklis, Hamid I. Akbarali, Graeme Henderson and William L. Dewey
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 45-52; DOI: https://doi.org/10.1124/jpet.117.241083

  9. Henriksen, Kim

    1. The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes
      Sara T. Hjuler, Sofie Gydesen, Kim V. Andreassen, Morten A. Karsdal and Kim Henriksen
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 24-30; DOI: https://doi.org/10.1124/jpet.117.241281

  10. Hess, Patrick

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  11. Hiranita, Takato

    1. σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration
      Takato Hiranita, Weimin C. Hong, Theresa Kopajtic and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 2-13; DOI: https://doi.org/10.1124/jpet.117.241109

  12. Hjuler, Sara T.

    1. The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes
      Sara T. Hjuler, Sofie Gydesen, Kim V. Andreassen, Morten A. Karsdal and Kim Henriksen
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 24-30; DOI: https://doi.org/10.1124/jpet.117.241281

  13. Hoffmann, Torsten

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  14. Hong, Weimin C.

    1. σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration
      Takato Hiranita, Weimin C. Hong, Theresa Kopajtic and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 2-13; DOI: https://doi.org/10.1124/jpet.117.241109

  15. Hoshi, Naoto

    1. XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels that Favor Activated Single Subunits
      Derek L Greene, Seungwoo Kang and Naoto Hoshi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 177-185; DOI: https://doi.org/10.1124/jpet.117.241679

  16. Hutter-Paier, Birgit

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

I

  1. Iglarz, Marc

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  2. Iizuka, Seiichi

    1. Open Access
      Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
      Yumi Harada, Seiichi Iizuka, Yayoi Saegusa, Sachiko Mogami, Naoki Fujitsuka and Tomohisa Hattori
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 78-84; DOI: https://doi.org/10.1124/jpet.117.240630

  3. Ilch, Christopher P.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

J

  1. Jacob, Joanna C.

    1. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone
      Joanna C. Jacob, Justin L. Poklis, Hamid I. Akbarali, Graeme Henderson and William L. Dewey
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 45-52; DOI: https://doi.org/10.1124/jpet.117.241083

  2. Jarosh, Michael

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  3. Jeter-Jones, Sabrina

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  4. Jiang, Xuewen

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  5. Jiménez-Altayó, Francesc

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  6. Jin, Najia

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  7. Johnson, Danielle

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  8. Johnson, Graham

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  9. Jones, Cameron

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

K

  1. Kang, Seungwoo

    1. XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels that Favor Activated Single Subunits
      Derek L Greene, Seungwoo Kang and Naoto Hoshi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 177-185; DOI: https://doi.org/10.1124/jpet.117.241679

  2. Karsdal, Morten A.

    1. The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes
      Sara T. Hjuler, Sofie Gydesen, Kim V. Andreassen, Morten A. Karsdal and Kim Henriksen
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 24-30; DOI: https://doi.org/10.1124/jpet.117.241281

  3. Katz, Jonathan L.

    1. σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration
      Takato Hiranita, Weimin C. Hong, Theresa Kopajtic and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 2-13; DOI: https://doi.org/10.1124/jpet.117.241109

  4. Kim, Doo Y.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  5. Kinoshita, Junzo

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

  6. Kiser, Philip D.

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

  7. Klee, Justin B.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  8. Kleinschmidt, Martin

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  9. Kopajtic, Theresa

    1. σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration
      Takato Hiranita, Weimin C. Hong, Theresa Kopajtic and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 2-13; DOI: https://doi.org/10.1124/jpet.117.241109

  10. Kornecook, Thomas J.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  11. Kowala, Mark C.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  12. Kurat, Stephan

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

L

  1. Lazenka, Matthew F.

    1. Relief of Pain-Depressed Behavior in Rats by Activation of D1-Like Dopamine Receptors
      Matthew F. Lazenka, Kelen C. Freitas, Sydney Henck and S. Stevens Negus
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 14-23; DOI: https://doi.org/10.1124/jpet.117.240796

  2. Lee, Josie H.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  3. Lehto, Sonya G.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  4. Leohr, Jennifer K.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  5. Lichtman, A. H.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  6. Ligutti, Joseph

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  7. Lin, Jiunn H.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  8. Liu, Dong

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  9. Lues, Inge

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  10. Luffer-Atlas, Debra

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  11. Luo, M. Jane

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  12. Luther, Jason

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

M

  1. Mabry, Thomas E.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  2. Masliah, Deborah

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  3. Matson, David

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  4. Menyhart, Katalin

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  5. Meyer, Antje

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  6. Milligan, Paul L.

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  7. Mobley, William C.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  8. Mogami, Sachiko

    1. Open Access
      Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
      Yumi Harada, Seiichi Iizuka, Yayoi Saegusa, Sachiko Mogami, Naoki Fujitsuka and Tomohisa Hattori
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 78-84; DOI: https://doi.org/10.1124/jpet.117.240630

  9. Monnier, Lucile

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  10. Monte, Louise

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  11. Morales, A. J.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  12. Morrison, Keith

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  13. Moyer, Bryan D.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  14. Mseeh, Faika

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

N

  1. Nayler, Oliver

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  2. Negus, S. S.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  3. Negus, S. Stevens

    1. Relief of Pain-Depressed Behavior in Rats by Activation of D1-Like Dopamine Receptors
      Matthew F. Lazenka, Kelen C. Freitas, Sydney Henck and S. Stevens Negus
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 14-23; DOI: https://doi.org/10.1124/jpet.117.240796
    2. Effects of Acute and Chronic Treatments with Dopamine D2 and D3 Receptor Ligands on Cocaine versus Food Choice in Rats
      Morgane Thomsen, Andrew C. Barrett, Paul Butler, S. Stevens Negus and S. Barak Caine
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 161-176; DOI: https://doi.org/10.1124/jpet.117.241141

  4. Nguyen, Phuong D.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

O

  1. Ortuno, Danny

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

P

  1. Palczewski, Krzysztof

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

  2. Pando, Miryam M.

    1. Regulation of δ Opioid Receptor-Mediated Signaling and Antinociception in Peripheral Sensory Neurons by Arachidonic Acid–Dependent 12/15-Lipoxygenase Metabolites
      Laura C. Sullivan, Teresa A. Chavera, Xiaoli Gao, Miryam M. Pando and Kelly A. Berg
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 200-209; DOI: https://doi.org/10.1124/jpet.117.241604

  3. Peachey, Neal S.

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

  4. Poklis, Justin L.

    1. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone
      Joanna C. Jacob, Justin L. Poklis, Hamid I. Akbarali, Graeme Henderson and William L. Dewey
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 45-52; DOI: https://doi.org/10.1124/jpet.117.241083

  5. Powell, David R.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

Q

  1. Quinti, Luisa

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

R

  1. Rawlins, David B.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  2. Reidy, Charles

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  3. Rissman, Robert A.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  4. Roberts, John

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  5. Roppolo, James R.

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  6. Rynearson, Kevin D.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

S

  1. Saegusa, Yayoi

    1. Open Access
      Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
      Yumi Harada, Seiichi Iizuka, Yayoi Saegusa, Sachiko Mogami, Naoki Fujitsuka and Tomohisa Hattori
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 78-84; DOI: https://doi.org/10.1124/jpet.117.240630

  2. Santos-Eichler, Rosangela Aparecida

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  3. Schilling, Stephan

    1. Open Access
      Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer’s Disease—Studies on Relation to Effective Target Occupancy
      Torsten Hoffmann, Antje Meyer, Ulrich Heiser, Stephan Kurat, Livia Böhme, Martin Kleinschmidt, Karl-Ulrich Bühring, Birgit Hutter-Paier, Martina Farcher, Hans-Ulrich Demuth, Inge Lues and Stephan Schilling
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 119-130; DOI: https://doi.org/10.1124/jpet.117.240614

  4. Shen, Bing

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  5. Smith, Melinda G.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  6. Strobel, Eric D.

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  7. Sullivan, Laura C.

    1. Regulation of δ Opioid Receptor-Mediated Signaling and Antinociception in Peripheral Sensory Neurons by Arachidonic Acid–Dependent 12/15-Lipoxygenase Metabolites
      Laura C. Sullivan, Teresa A. Chavera, Xiaoli Gao, Miryam M. Pando and Kelly A. Berg
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 200-209; DOI: https://doi.org/10.1124/jpet.117.241604

T

  1. Taborn, Kristin

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  2. Tai, Changfeng

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  3. Tanzi, Rudolph E.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  4. Thomas, B. F.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  5. Thompson, Andrea

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  6. Thomsen, Morgane

    1. Effects of Acute and Chronic Treatments with Dopamine D2 and D3 Receptor Ligands on Cocaine versus Food Choice in Rats
      Morgane Thomsen, Andrew C. Barrett, Paul Butler, S. Stevens Negus and S. Barak Caine
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 161-176; DOI: https://doi.org/10.1124/jpet.117.241141

  7. Tochtrop, Gregory P.

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

U

  1. Uy, Jamie

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

V

  1. Vila, Elisabet

    1. Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats
      Priscila Xavier Araujo, Tiago Januário Costa, Cinthya Echem, Maria Aparecida de Oliveira, Rosangela Aparecida Santos-Eichler, Lucas Giglio Colli, Francesc Jiménez-Altayó, Elisabet Vila, Eliana Hiromi Akamine, Ana Paula Dantas, Graziela Scalianti Ceravolo and Maria Helena Catelli de Carvalho
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 98-107; DOI: https://doi.org/10.1124/jpet.117.240465

  2. Vo, Uyen

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

W

  1. Wagner, Steven L.

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  2. Wang, Hai-Tao

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  3. Wang, Jicheng

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  4. Wang, Jinti

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  5. Wanner, Daniel

    1. Open Access
      Selexipag Active Metabolite ACT-333679 Displays Strong Anticontractile and Antiremodeling Effects but Low β-Arrestin Recruitment and Desensitization Potential
      John Gatfield, Katalin Menyhart, Daniel Wanner, Carmela Gnerre, Lucile Monnier, Keith Morrison, Patrick Hess, Marc Iglarz, Martine Clozel and Oliver Nayler
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 186-199; DOI: https://doi.org/10.1124/jpet.116.239665

  6. Weed, Peter F.

    1. Preference for an Opioid/Benzodiazepine Mixture over an Opioid Alone Using a Concurrent Choice Procedure in Rhesus Monkeys
      Peter F. Weed, Charles P. France and Lisa R. Gerak
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 59-66; DOI: https://doi.org/10.1124/jpet.117.240200

  7. Weiss, Matthew M.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  8. Wiley, J. L.

    1. Apparent CB1 Receptor Rimonabant Affinity Estimates: Combination with THC and Synthetic Cannabinoids in the Mouse In Vivo Triad Model
      T. W. Grim, A. J. Morales, B. F. Thomas, J. L. Wiley, G. W. Endres, S. S. Negus and A. H. Lichtman
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 210-218; DOI: https://doi.org/10.1124/jpet.117.240192

  9. Wilson, Alan

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

X

  1. Xia, Weiming

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  2. Xiong, Wendy

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  3. Xu, Jiang-Ping

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

Y

  1. Yin, Ruoyuan

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  2. Yu, Michelle

    1. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats
      Jamie Uy, Michelle Yu, Xuewen Jiang, Cameron Jones, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat and Changfeng Tai
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 53-58; DOI: https://doi.org/10.1124/jpet.117.240895

  3. Yu, Violeta

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  4. Yu, Xiaohong

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

Z

  1. Zambrowicz, Brian

    1. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
      David R. Powell, Melinda G. Smith, Deon D. Doree, Angela L. Harris, Jennifer Greer, Christopher M. DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G. Carson, Nicole C. Goodwin, Bryce A. Harrison, David B. Rawlins, Eric D. Strobel, Suma Gopinathan, Alan Wilson, Faika Mseeh, Brian Zambrowicz and Zhi-Ming Ding
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 85-97; DOI: https://doi.org/10.1124/jpet.117.240820

  2. Zhang, Can

    1. Open Access
      Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
      Steven L. Wagner, Kevin D. Rynearson, Steven K. Duddy, Can Zhang, Phuong D. Nguyen, Ann Becker, Uyen Vo, Deborah Masliah, Louise Monte, Justin B. Klee, Corinne M. Echmalian, Weiming Xia, Luisa Quinti, Graham Johnson, Jiunn H. Lin, Doo Y. Kim, William C. Mobley, Robert A. Rissman and Rudolph E. Tanzi
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 31-44; DOI: https://doi.org/10.1124/jpet.117.240861

  3. Zhang, Jianye

    1. Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Rational Tuning of Visual Cycle Modulator Pharmacodynamics
      Philip D. Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S. Peachey, Gregory P. Tochtrop and Krzysztof Palczewski
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 131-145; DOI: https://doi.org/10.1124/jpet.117.240721

  4. Zhang, Yuke

    1. Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet–Induced Obese Rats
      Thomas B. Estridge, Asim B. Dey, Charles Reidy, Xiaohong Yu, Yuke Zhang, Maryalice Hartley, Paul L. Milligan, Najia Jin, Mark C. Kowala, Jennifer K. Leohr, Adrian J. Fretland, Thomas E. Mabry, Debra Luffer-Atlas and M. Jane Luo
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 108-118; DOI: https://doi.org/10.1124/jpet.117.240242

  5. Zheng, Wenhua

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  6. Zhou, Zhong-Zhen

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608

  7. Zhu, Dawn X. D.

    1. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7
      Thomas J. Kornecook, Ruoyuan Yin, Stephen Altmann, Xuhai Be, Virginia Berry, Christopher P. Ilch, Michael Jarosh, Danielle Johnson, Josie H. Lee, Sonya G. Lehto, Joseph Ligutti, Dong Liu, Jason Luther, David Matson, Danny Ortuno, John Roberts, Kristin Taborn, Jinti Wang, Matthew M. Weiss, Violeta Yu, Dawn X. D. Zhu, Robert T. Fremeau and Bryan D. Moyer
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 146-160; DOI: https://doi.org/10.1124/jpet.116.239590

  8. Zou, Zheng-Qiang

    1. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition
      Zheng-Qiang Zou, Jia-Jia Chen, Hong-Fang Feng, Yu-Fang Cheng, Hai-Tao Wang, Zhong-Zhen Zhou, Hai-Biao Guo, Wenhua Zheng and Jiang-Ping Xu
      Journal of Pharmacology and Experimental Therapeutics July 2017, 362 (1) 67-77; DOI: https://doi.org/10.1124/jpet.116.239608
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