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Index by author

May 01, 2017; Volume 361,Issue 2

A

  1. Aboutanos, Michel

    1. Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k
      Valerie Plant, Dan W. Parrish, Ashley Limkemann, Paula Ferrada, Michel Aboutanos and Martin J. Mangino
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 334-340; DOI: https://doi.org/10.1124/jpet.116.239822

  2. Acuña, Claudia

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  3. Alfaro, Jennifer

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  4. Almirez, Ramona G.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  5. Alpert, Carla

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  6. Amaro, Marina

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  7. Amory, John K.

    1. Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
      Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory and Nina Isoherranen
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 246-258; DOI: https://doi.org/10.1124/jpet.117.240523

  8. Avila, Patricio

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

B

  1. Barde, Anup

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  2. Bays, Nathan

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  3. Belmar, Sebastián

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  4. Bernales, Sebastián

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  5. Birnbaum, Morris J.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  6. Bollinger, Eliza

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  7. Boucher, Germaine G.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  8. Bui, Khanh

    1. Open Access
      Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
      Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza and Michael Eldon
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 280-291; DOI: https://doi.org/10.1124/jpet.116.239061

  9. Byford, Alan

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

C

  1. Calabrese, Matthew F.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Cameron, Kimberly O.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  3. Cao, Fengyan

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

  4. Cattaneo, Christophe

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

  5. Chagoya de Sánchez, Victoria

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

  6. Chakravarthy, Kalyan

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  7. Chakravarty, Sarvajit

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  8. Chauhan, Shailender

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  9. Chávez, Enrique

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

  10. Chiu, Chi-Sung

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  11. Cialdea, Katherine

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  12. Clozel, Martine

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

  13. Cokorinos, Emily

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  14. Coskran, Timothy M.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

D

  1. Dandliker, Peter J.

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  2. DaSilva-Jardine, Paul

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  3. Delgado, Luz

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  4. Deshmukh, Sujal V.

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  5. Dinsmore, Christopher

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  6. Domínguez-López, Mariana

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

  7. Dorosh, Lauren

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

E

  1. Edmonds, David J.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Eldon, Michael

    1. Open Access
      Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
      Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza and Michael Eldon
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 280-291; DOI: https://doi.org/10.1124/jpet.116.239061

  3. Elwood, Fiona

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

F

  1. Ferrada, Paula

    1. Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k
      Valerie Plant, Dan W. Parrish, Ashley Limkemann, Paula Ferrada, Michel Aboutanos and Martin J. Mangino
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 334-340; DOI: https://doi.org/10.1124/jpet.116.239822

  2. Floettmann, Eike

    1. Open Access
      Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
      Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza and Michael Eldon
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 280-291; DOI: https://doi.org/10.1124/jpet.116.239061

  3. Flores, Camila

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  4. Fuentealba, Glenda

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

G

  1. Gaete, Diana

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  2. Gandhok, Harmeet

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  3. Genung, Nathan E.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  4. Goldenblatt, Peter

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  5. Gong, Yanqing

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

H

  1. Hague, Chris

    1. Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells
      Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella and Chris Hague
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 219-228; DOI: https://doi.org/10.1124/jpet.116.237255

  2. Harris, Dorathy-Ann

    1. Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells
      Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella and Chris Hague
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 219-228; DOI: https://doi.org/10.1124/jpet.116.237255

  3. Hess, Patrick

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

  4. Hung, David T.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

I

  1. Iglarz, Marc

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

  2. Ikushiro, Shin’ichi

    1. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382

  3. Ishii, Yuji

    1. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382

  4. Isoherranen, Nina

    1. Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
      Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory and Nina Isoherranen
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 246-258; DOI: https://doi.org/10.1124/jpet.117.240523

  5. Ivanovska, Irena

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

J

  1. Jatkar, Aditi

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Jing, Jing

    1. Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
      Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory and Nina Isoherranen
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 246-258; DOI: https://doi.org/10.1124/jpet.117.240523

  3. José-Nuñez, Concepción

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

K

  1. Kalgutkar, Amit S.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Kanno, Stacy

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  3. Kariv, Ilona

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  4. Katus, Hugo A.

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287

  5. Klappenbach, Joel

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  6. Koepple, Christoph

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287

  7. Kraybill, Brian

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  8. Kreeger, John M.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  9. Kurita, Ayumi

    1. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382

  10. Kurumbail, Ravi G.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

L

  1. Lee, Hyun-Hee

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  2. Lee, Kyung-Soon

    1. Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells
      Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella and Chris Hague
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 219-228; DOI: https://doi.org/10.1124/jpet.116.237255

  3. Liby, Karen T.

    1. Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing
      Joseph W. Zagorski, Tyler P. Maser, Karen T. Liby and Cheryl E. Rockwell
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 259-267; DOI: https://doi.org/10.1124/jpet.116.238899

  4. Limkemann, Ashley

    1. Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k
      Valerie Plant, Dan W. Parrish, Ashley Limkemann, Paula Ferrada, Michel Aboutanos and Martin J. Mangino
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 334-340; DOI: https://doi.org/10.1124/jpet.116.239822

  5. Lozano-Rosas, María Guadalupe

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

M

  1. Maciejewski, Benjamin S

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Mackenzie, Peter I.

    1. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382

  3. Mangino, Martin J.

    1. Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k
      Valerie Plant, Dan W. Parrish, Ashley Limkemann, Paula Ferrada, Michel Aboutanos and Martin J. Mangino
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 334-340; DOI: https://doi.org/10.1124/jpet.116.239822

  4. Maser, Tyler P.

    1. Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing
      Joseph W. Zagorski, Tyler P. Maser, Karen T. Liby and Cheryl E. Rockwell
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 259-267; DOI: https://doi.org/10.1124/jpet.116.238899

  5. McCullagh, Emma

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  6. Miller, Russell A.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  7. Miyauchi, Yuu

    1. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382

  8. Monetti, Mara

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

N

  1. Nayak, Anjan K.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  2. Nelson, Cara

    1. Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
      Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory and Nina Isoherranen
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 246-258; DOI: https://doi.org/10.1124/jpet.117.240523

O

  1. Opsahl, Alan C.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

P

  1. Paik, Jisun

    1. Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
      Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory and Nina Isoherranen
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 246-258; DOI: https://doi.org/10.1124/jpet.117.240523

  2. Pan, Bo-Sheng

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  3. Park, Ji-Min

    1. Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells
      Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella and Chris Hague
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 219-228; DOI: https://doi.org/10.1124/jpet.116.237255

  4. Parrish, Dan W.

    1. Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k
      Valerie Plant, Dan W. Parrish, Ashley Limkemann, Paula Ferrada, Michel Aboutanos and Martin J. Mangino
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 334-340; DOI: https://doi.org/10.1124/jpet.116.239822

  5. Pasquali, Anne

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

  6. Patel, Dhananjay

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  7. Payza, Kemal

    1. Open Access
      Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
      Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza and Michael Eldon
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 280-291; DOI: https://doi.org/10.1124/jpet.116.239061

  8. Pérez de Arce, Felipe

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  9. Pham, Son M.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  10. Piesvaux, Jennifer

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  11. Plant, Valerie

    1. Low-Volume Resuscitation for Hemorrhagic Shock: Understanding the Mechanism of PEG-20k
      Valerie Plant, Dan W. Parrish, Ashley Limkemann, Paula Ferrada, Michel Aboutanos and Martin J. Mangino
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 334-340; DOI: https://doi.org/10.1124/jpet.116.239822

  12. Pujala, Brahmam

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

Q

  1. Qu, Yujie

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  2. Quinn, Kevin P.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

R

  1. Rai, Roopa

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  2. Rajamohan, Francis

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  3. Reyes, Allan

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  4. Rivkin, Alexey

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  5. Rockwell, Cheryl E.

    1. Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing
      Joseph W. Zagorski, Tyler P. Maser, Karen T. Liby and Cheryl E. Rockwell
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 259-267; DOI: https://doi.org/10.1124/jpet.116.238899

  6. Rodríguez-Aguilera, Jesús Rafael

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

  7. Rolph, Tim

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

S

  1. Salatto, Christopher T.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Scherer, Daniel

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287

  3. Scholz, Eberhard

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287

  4. Scott, Mark E.

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  5. Seyler, Claudia

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287

  6. Sharma, Vijay K.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  7. Shavnya, Andre

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  8. Shirasaka, Yoshiyuki

    1. Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions
      Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory and Nina Isoherranen
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 246-258; DOI: https://doi.org/10.1124/jpet.117.240523

  9. Slipetz, Deborah

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  10. Sostek, Mark

    1. Open Access
      Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
      Eike Floettmann, Khanh Bui, Mark Sostek, Kemal Payza and Michael Eldon
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 280-291; DOI: https://doi.org/10.1124/jpet.116.239061

  11. Stella, Nephi

    1. Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells
      Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella and Chris Hague
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 219-228; DOI: https://doi.org/10.1124/jpet.116.237255

  12. Strasser, Daniel S.

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

T

  1. Tang, Hao

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  2. Tao, Lijun

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

  3. Tess, David A.

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  4. Thomas, Dierk

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287

  5. Trensz, Frederic

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

  6. Tuena de Gómez-Puyou, Marietta

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

U

  1. Upendra, T. V. R.

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

  2. Ureta, Gonzalo

    1. Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies
      Jennifer Alfaro, Felipe Pérez de Arce, Sebastián Belmar, Glenda Fuentealba, Patricio Avila, Gonzalo Ureta, Camila Flores, Claudia Acuña, Luz Delgado, Diana Gaete, Brahmam Pujala, Anup Barde, Anjan K. Nayak, T. V. R. Upendra, Dhananjay Patel, Shailender Chauhan, Vijay K. Sharma, Stacy Kanno, Ramona G. Almirez, David T. Hung, Sarvajit Chakravarty, Roopa Rai, Sebastián Bernales, Kevin P. Quinn, Son M. Pham and Emma McCullagh
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 312-321; DOI: https://doi.org/10.1124/jpet.116.238022

V

  1. Velasco-Loyden, Gabriela

    1. Functional, Metabolic, and Dynamic Mitochondrial Changes in the Rat Cirrhosis-Hepatocellular Carcinoma Model and the Protective Effect of IFC-305
      Enrique Chávez, María Guadalupe Lozano-Rosas, Mariana Domínguez-López, Gabriela Velasco-Loyden, Jesús Rafael Rodríguez-Aguilera, Concepción José-Nuñez, Marietta Tuena de Gómez-Puyou and Victoria Chagoya de Sánchez
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 292-302; DOI: https://doi.org/10.1124/jpet.116.239301

  2. Vercauteren, Magali

    1. Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention
      Magali Vercauteren, Frederic Trensz, Anne Pasquali, Christophe Cattaneo, Daniel S. Strasser, Patrick Hess, Marc Iglarz and Martine Clozel
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 322-333; DOI: https://doi.org/10.1124/jpet.116.234930

W

  1. Ward, Jessica

    1. Selective Activation of AMPK β1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy
      Christopher T. Salatto, Russell A. Miller, Kimberly O. Cameron, Emily Cokorinos, Allan Reyes, Jessica Ward, Matthew F. Calabrese, Ravi G. Kurumbail, Francis Rajamohan, Amit S. Kalgutkar, David A. Tess, Andre Shavnya, Nathan E. Genung, David J. Edmonds, Aditi Jatkar, Benjamin S Maciejewski, Marina Amaro, Harmeet Gandhok, Mara Monetti, Katherine Cialdea, Eliza Bollinger, John M. Kreeger, Timothy M. Coskran, Alan C. Opsahl, Germaine G. Boucher, Morris J. Birnbaum, Paul DaSilva-Jardine and Tim Rolph
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 303-311; DOI: https://doi.org/10.1124/jpet.116.237925

  2. Witter, David J.

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

X

  1. Xie, Haifeng

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

  2. Xu, Cong

    1. Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells
      Dorathy-Ann Harris, Ji-Min Park, Kyung-Soon Lee, Cong Xu, Nephi Stella and Chris Hague
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 219-228; DOI: https://doi.org/10.1124/jpet.116.237255

Y

  1. Yamada, Hideyuki

    1. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation
      Ayumi Kurita, Yuu Miyauchi, Shin’ichi Ikushiro, Peter I. Mackenzie, Hideyuki Yamada and Yuji Ishii
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 199-208; DOI: https://doi.org/10.1124/jpet.117.240382

  2. Yang, Jinyu

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

Z

  1. Zagorski, Joseph W.

    1. Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H2O2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing
      Joseph W. Zagorski, Tyler P. Maser, Karen T. Liby and Cheryl E. Rockwell
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 259-267; DOI: https://doi.org/10.1124/jpet.116.238899

  2. Zhang, Chaofeng

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

  3. Zhang, Mian

    1. Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Mogroside IIIE, a Novel Anti-Fibrotic Compound, Reduces Pulmonary Fibrosis through Toll-Like Receptor 4 Pathways
      Lijun Tao, Jinyu Yang, Fengyan Cao, Haifeng Xie, Mian Zhang, Yanqing Gong and Chaofeng Zhang
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 268-279; DOI: https://doi.org/10.1124/jpet.116.239137

  4. Zielstorff, Mark

    1. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor
      Fiona Elwood, David J. Witter, Jennifer Piesvaux, Brian Kraybill, Nathan Bays, Carla Alpert, Peter Goldenblatt, Yujie Qu, Irena Ivanovska, Hyun-Hee Lee, Chi-Sung Chiu, Hao Tang, Mark E. Scott, Sujal V. Deshmukh, Mark Zielstorff, Alan Byford, Kalyan Chakravarthy, Lauren Dorosh, Alexey Rivkin, Joel Klappenbach, Bo-Sheng Pan, Ilona Kariv, Christopher Dinsmore, Deborah Slipetz and Peter J. Dandliker
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 229-244; DOI: https://doi.org/10.1124/jpet.116.239723

  5. Zitron, Edgar

    1. Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference
      Christoph Koepple, Daniel Scherer, Claudia Seyler, Eberhard Scholz, Dierk Thomas, Hugo A. Katus and Edgar Zitron
      Journal of Pharmacology and Experimental Therapeutics May 2017, 361 (2) 209-218; DOI: https://doi.org/10.1124/jpet.116.238287
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