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Research ArticleNeuropharmacology

Antidepressant Potential of (R)-Ketamine in Rodent Models: Comparison with (S)-Ketamine

Kenichi Fukumoto, Hidetoh Toki, Michihiko Iijima, Takashi Hashihayata, Jun-ichi Yamaguchi, Kenji Hashimoto and Shigeyuki Chaki
Journal of Pharmacology and Experimental Therapeutics April 2017, 361 (1) 9-16; DOI: https://doi.org/10.1124/jpet.116.239228
Kenichi Fukumoto
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Hidetoh Toki
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Michihiko Iijima
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Takashi Hashihayata
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Jun-ichi Yamaguchi
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Kenji Hashimoto
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Shigeyuki Chaki
Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
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Article Information

vol. 361 no. 1 9-16
DOI 
https://doi.org/10.1124/jpet.116.239228
PubMed 
28115553

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 24, 2016
  • Accepted January 18, 2017
  • Published online February 27, 2017.

Article Versions

  • Earlier version (January 23, 2017 - 10:33).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kenichi Fukumoto,
  2. Hidetoh Toki,
  3. Michihiko Iijima,
  4. Takashi Hashihayata,
  5. Jun-ichi Yamaguchi,
  6. Kenji Hashimoto, and
  7. Shigeyuki Chaki
  1. Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japan (K.F., H.T., M.I., T.H., J.Y., S.C.); and Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan (K.H.)
  1. Address correspondence to:
    Dr. Shigeyuki Chaki, Research Headquarters, Taisho Pharmaceutical Co., Ltd., 1-403, Yoshino-cho, Kita-ku, Saitama, Japan. E-mail: s-chaki{at}so.taisho.co.jp
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Journal of Pharmacology and Experimental Therapeutics: 361 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 361, Issue 1
1 Apr 2017
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Research ArticleNeuropharmacology

Antidepressant Effects of (R)-Ketamine

Kenichi Fukumoto, Hidetoh Toki, Michihiko Iijima, Takashi Hashihayata, Jun-ichi Yamaguchi, Kenji Hashimoto and Shigeyuki Chaki
Journal of Pharmacology and Experimental Therapeutics April 1, 2017, 361 (1) 9-16; DOI: https://doi.org/10.1124/jpet.116.239228

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Research ArticleNeuropharmacology

Antidepressant Effects of (R)-Ketamine

Kenichi Fukumoto, Hidetoh Toki, Michihiko Iijima, Takashi Hashihayata, Jun-ichi Yamaguchi, Kenji Hashimoto and Shigeyuki Chaki
Journal of Pharmacology and Experimental Therapeutics April 1, 2017, 361 (1) 9-16; DOI: https://doi.org/10.1124/jpet.116.239228
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