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Research ArticleCardiovascular

PDE5 Inhibitor Tadalafil and Hydroxychloroquine Cotreatment Provides Synergistic Protection against Type 2 Diabetes and Myocardial Infarction in Mice

Rui Wang, Lei Xi and Rakesh C. Kukreja
Journal of Pharmacology and Experimental Therapeutics April 2017, 361 (1) 29-38; DOI: https://doi.org/10.1124/jpet.116.239087
Rui Wang
Pauley Heart Center, Division of Cardiology, Virginia Commonwealth University. Richmond, Virginia
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Lei Xi
Pauley Heart Center, Division of Cardiology, Virginia Commonwealth University. Richmond, Virginia
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Rakesh C. Kukreja
Pauley Heart Center, Division of Cardiology, Virginia Commonwealth University. Richmond, Virginia
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Article Information

vol. 361 no. 1 29-38
DOI 
https://doi.org/10.1124/jpet.116.239087
PubMed 
28123046

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 18, 2016
  • Accepted January 23, 2017
  • Published online February 27, 2017.

Article Versions

  • Earlier version (January 25, 2017 - 14:02).
  • Earlier version (January 26, 2017 - 07:56).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Rui Wang,
  2. Lei Xi, and
  3. Rakesh C. Kukreja
  1. Pauley Heart Center, Division of Cardiology, Virginia Commonwealth University. Richmond, Virginia
  1. Address correspondence to:
    Dr. Rakesh C. Kukreja, Scientific Director, Pauley Heart Center, Professor of Medicine, Physiology, Biochemistry, Division of Cardiology, Box 980204, Virginia Commonwealth University, 1101 East Marshall Street, Room 7-020D, Richmond, VA 23298-0204. E-mail: rakesh.kukreja{at}vcuhealth.org
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Journal of Pharmacology and Experimental Therapeutics: 361 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 361, Issue 1
1 Apr 2017
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Research ArticleCardiovascular

Tadalafil and Hydroxychloroquine Protect Diabetic Heart

Rui Wang, Lei Xi and Rakesh C. Kukreja
Journal of Pharmacology and Experimental Therapeutics April 1, 2017, 361 (1) 29-38; DOI: https://doi.org/10.1124/jpet.116.239087

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Research ArticleCardiovascular

Tadalafil and Hydroxychloroquine Protect Diabetic Heart

Rui Wang, Lei Xi and Rakesh C. Kukreja
Journal of Pharmacology and Experimental Therapeutics April 1, 2017, 361 (1) 29-38; DOI: https://doi.org/10.1124/jpet.116.239087
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