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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

March 01, 2017; Volume 360,Issue 3

Cardiovascular

  • You have access
    Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury
    Boyd R. Rorabaugh, Bandana Chakravarti, Nathaniel W. Mabe, Sarah L. Seeley, Albert D. Bui, Jianqi Yang, Stephanie W. Watts, Richard R. Neubig and Rory A. Fisher
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 409-416; DOI: https://doi.org/10.1124/jpet.116.238345
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    Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1
    Deping Kong, Juanjuan Li, Yujun Shen, Guizhu Liu, Shengkai Zuo, Bo Tao, Yong Ji, Ankang Lu, Michael Lazarus, Richard M. Breyer and Ying Yu
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 435-444; DOI: https://doi.org/10.1124/jpet.116.238261
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    Factor XIIa as a Novel Target for Thrombosis: Target Engagement Requirement and Efficacy in a Rabbit Model of Microembolic Signals
    Christopher M. Barbieri, Xinkang Wang, Weizhen Wu, Xueping Zhou, Aimie M. Ogawa, Kim O’Neill, Donald Chu, Gino Castriota, Dietmar A. Seiffert, David E. Gutstein and Zhu Chen
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 466-475; DOI: https://doi.org/10.1124/jpet.116.238493
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    Inhibition of Factor XIa Reduces the Frequency of Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
    Xinkang Wang, Stan Kurowski, Weizhen Wu, Gino A. Castriota, Xueping Zhou, Lin Chu, Kenneth P. Ellsworth, Donald Chu, Scott Edmondson, Amjad Ali, Patrick Andre, Dietmar Seiffert, Mark Erion, David E. Gutstein and Zhu Chen
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 476-483; DOI: https://doi.org/10.1124/jpet.116.238600

Cellular and Molecular

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    Regulation of Chemokine Signal Integration by Activator of G-Protein Signaling 4 (AGS4)
    William G. Robichaux, Melissa Branham-O’Connor, Il-Young Hwang, Ali Vural, Johne H. Kehrl and Joe B. Blumer
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 424-433; DOI: https://doi.org/10.1124/jpet.116.238436

Drug Discovery and Translational Medicine

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    Characterizing Gemcitabine Effects Administered as Single Agent or Combined with Carboplatin in Mice Pancreatic and Ovarian Cancer Xenografts: A Semimechanistic Pharmacokinetic/Pharmacodynamics Tumor Growth-Response Model
    Maria Garcia-Cremades, Celine Pitou, Philip W. Iversen and Iñaki F. Troconiz
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 445-456; DOI: https://doi.org/10.1124/jpet.116.237610

Metabolism, Transport, and Pharmacogenomics

  • Delineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations
    Open Access
    Delineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations
    Daniel Scotcher, Christopher R. Jones, Aleksandra Galetin and Amin Rostami-Hodjegan
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 484-495; DOI: https://doi.org/10.1124/jpet.116.237438

Neuropharmacology

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    Inhibition of Leukotriene B4 Action Mitigates Intracerebral Hemorrhage-Associated Pathological Events in Mice
    Masanori Hijioka, Junpei Anan, Hayato Ishibashi, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Tomoaki Koga, Takehiko Yokomizo, Takao Shimizu and Hiroshi Katsuki
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 399-408; DOI: https://doi.org/10.1124/jpet.116.238824
  • Dissecting the Influence of Two Structural Substituents on the Differential Neurotoxic Effects of Acute Methamphetamine and Mephedrone Treatment on Dopamine Nerve Endings with the Use of 4-Methylmethamphetamine and Methcathinone
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    Dissecting the Influence of Two Structural Substituents on the Differential Neurotoxic Effects of Acute Methamphetamine and Mephedrone Treatment on Dopamine Nerve Endings with the Use of 4-Methylmethamphetamine and Methcathinone
    John H. Anneken, Mariana Angoa-Pérez, Girish C. Sati, David Crich and Donald M. Kuhn
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 417-423; DOI: https://doi.org/10.1124/jpet.116.237768
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    Quantification of ONO-2952 Occupancy of 18-kDaTranslocator Protein in Conscious Monkey Brains using Positron Emission Tomography
    Katsukuni Mitsui, Noriko Morimoto, Tomohiro Niwa, Yoshiyuki Yamaura, Hiroyuki Ohba, Hideo Tsukada and Seishi Katsumata
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 457-465; DOI: https://doi.org/10.1124/jpet.116.238568

Toxicology

  • Open Access
    Activation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and Hispidulin
    Anyamanee Chaiprasongsuk, Jinaphat Lohakul, Kitipong Soontrapa, Somponnat Sampattavanich, Pravit Akarasereenont and Uraiwan Panich
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 388-398; DOI: https://doi.org/10.1124/jpet.116.238048

Letters to the Editor

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    Rosuvastatin and Its Evolving Role as a Vascular Remodeling and Antiproliferative Agent in Different Systemic Malignancies
    Shailendra Kapoor
    Journal of Pharmacology and Experimental Therapeutics March 2017, 360 (3) 434; DOI: https://doi.org/10.1124/jpet.116.239400
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 360 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 360, Issue 3
1 Mar 2017
  • Table of Contents
  • Table of Contents (PDF)
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  • Index by author
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  • Cardiovascular
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  • Potential Clinical Uses of CBG
  • Ocular Drug Delivery: Past, Present, and Future
  • Rho GTPase–Pathway Inhibitor Reduces Markers of Fibrosis
  • Nose-to-Brain Delivery
  • SEP-363856, a Novel, Non-D2 Psychotropic Agent
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