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Research ArticleDrug Discovery and Translational Medicine

Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis

Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

Article Information

vol. 360 no. 1 1-13
DOI 
https://doi.org/10.1124/jpet.116.237156
PubMed 
27754931
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 9, 2016
  • Accepted October 14, 2016
  • Published online December 5, 2016.

Article Versions

Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Gretchen Bain,
  2. Kristen E. Shannon,
  3. Fei Huang,
  4. Janice Darlington,
  5. Lance Goulet,
  6. Patricia Prodanovich,
  7. Gina L. Ma,
  8. Angelina M. Santini,
  9. Adam J. Stein,
  10. Dave Lonergan,
  11. Christopher D. King,
  12. Imelda Calderon,
  13. Andiliy Lai,
  14. John H. Hutchinson, and
  15. Jilly F. Evans
  1. PharmAkea Inc, San Diego, California (G.B., K.E.S., F.H., J.D., L.G., P.P., G.L.M., A.M.S., D.L., C.D.K., I.C., A.L., J.H.H., J.E.F.); Cayman Chemical Company, Ann Arbor, Michigan (A.J.S.)
  1. Address correspondence to:
    Dr. Gretchen Bain, 3030 Bunker Hill Street, Suite 300, San Diego, CA 92109. E-mail: gbain{at}pharmakea.com
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Research ArticleDrug Discovery and Translational Medicine

Autotaxin Inhibition Attenuates Mouse Liver Fibrosis

Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
Journal of Pharmacology and Experimental Therapeutics January 1, 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156
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