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Index by author

January 01, 2017; Volume 360,Issue 1

A

  1. Adams, Benjamin L.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  2. Amagase, Kikuko

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  3. Anderson, Wesley H.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  4. Apland, James P.

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

  5. Arnaiz-Cot, Juan Jose

    1. Xanthohumol Modulates Calcium Signaling in Rat Ventricular Myocytes: Possible Antiarrhythmic Properties
      Juan Jose Arnaiz-Cot, Lars Cleemann and Martin Morad
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 239-248; DOI: https://doi.org/10.1124/jpet.116.236588

  6. Aroniadou-Anderjaska, Vassiliki

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

B

  1. Bain, Gretchen

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  2. Beck, James P.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  3. Beinborn, Martin

    1. Mutation-Induced Functional Alterations of CCR6
      Bina Julian, Kevin Gao, Benjamin N. Harwood, Martin Beinborn and Alan S. Kopin
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 106-116; DOI: https://doi.org/10.1124/jpet.116.237669

  4. Bowman, Melodi A.

    1. Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Nathan C. Mitchell, Melodi A. Bowman, Georgianna G. Gould, Wouter Koek and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 84-94; DOI: https://doi.org/10.1124/jpet.116.237305

  5. Braga, Maria F. M.

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

  6. Bruns, Robert F.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  7. Bu, Pengli

    1. Hormonal and Chemical Regulation of the Glut9 Transporter in Mice
      Pengli Bu, Yuan Le, Yue Zhang and Xingguo Cheng
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 206-214; DOI: https://doi.org/10.1124/jpet.116.237040

C

  1. Calderon, Imelda

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  2. Cao, Weibiao

    1. Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett’s Associated Esophageal Adenocarcinoma Cells
      Dan Li, Jie Hong and Weibiao Cao
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 14-22; DOI: https://doi.org/10.1124/jpet.116.236620

  3. Carano, Richard A. D.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  4. Chaudhry, Amarjit

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  5. Cheng, Xingguo

    1. Hormonal and Chemical Regulation of the Glut9 Transporter in Mice
      Pengli Bu, Yuan Le, Yue Zhang and Xingguo Cheng
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 206-214; DOI: https://doi.org/10.1124/jpet.116.237040

  6. Chow, Edwin C. Y.

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  7. Cirit, M.

    1. Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      Open Access
      Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495

  8. Claw, Katrina G.

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  9. Cleary, Yumi

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

  10. Cleemann, Lars

    1. Xanthohumol Modulates Calcium Signaling in Rat Ventricular Myocytes: Possible Antiarrhythmic Properties
      Juan Jose Arnaiz-Cot, Lars Cleemann and Martin Morad
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 239-248; DOI: https://doi.org/10.1124/jpet.116.236588

  11. Cohen, Michael P.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  12. Cramer, Jeffrey W.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  13. Crawford, James J.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  14. Crider, Amanda

    1. Estrogen Signaling as a Therapeutic Target in Neurodevelopmental Disorders
      Amanda Crider and Anilkumar Pillai
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 48-58; DOI: https://doi.org/10.1124/jpet.116.237412

D

  1. Dambach, Donna M.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  2. Darlington, Janice

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  3. Daws, Lynette C.

    1. Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Nathan C. Mitchell, Melodi A. Bowman, Georgianna G. Gould, Wouter Koek and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 84-94; DOI: https://doi.org/10.1124/jpet.116.237305

  4. DeLapp, Neil W.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  5. Deng, Liting

    1. Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture
      Liting Deng, Lindsay Ng, Tatsuya Ozawa and Nephi Stella
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 215-224; DOI: https://doi.org/10.1124/jpet.116.236968

  6. Do, Anh

    1. An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice
      Anh Do, Robert C. Reid, Rink-Jan Lohman, Matthew J. Sweet, David P. Fairlie and Abishek Iyer
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 140-151; DOI: https://doi.org/10.1124/jpet.116.236711

E

  1. Ellis, Justin

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  2. Elton, Terry S.

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  3. Emkey, Renee

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  4. Endo, Soma

    1. Urinary Excretion Contributes to Long-Lasting Blockade of Bladder Muscarinic Receptors by Imidafenacin: Effect of Bilateral Ureteral Ligation
      Yoshihiko Ito, Shiori Kuraoka, Soma Endo, Ayaka Takahashi, Satomi Onoue and Shizuo Yamada
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 69-74; DOI: https://doi.org/10.1124/jpet.116.236497

  5. Erickson, Rebecca I.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  6. Eshleman, Amy J.

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  7. Evans, David C.

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  8. Evans, Jilly F.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

F

  1. Fairlie, David P.

    1. An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice
      Anh Do, Robert C. Reid, Rink-Jan Lohman, Matthew J. Sweet, David P. Fairlie and Abishek Iyer
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 140-151; DOI: https://doi.org/10.1124/jpet.116.236711

  2. Falcone, Julie F.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  3. Figueiredo, Taiza H.

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

  4. Fowler, Stephen

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

  5. Furukawa, Junji

    1. Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
      Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984

G

  1. Gao, Kevin

    1. Mutation-Induced Functional Alterations of CCR6
      Bina Julian, Kevin Gao, Benjamin N. Harwood, Martin Beinborn and Alan S. Kopin
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 106-116; DOI: https://doi.org/10.1124/jpet.116.237669

  2. Gehlert, Donald R.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  3. Getman, Brian G.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  4. Gould, Georgianna G.

    1. Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Nathan C. Mitchell, Melodi A. Bowman, Georgianna G. Gould, Wouter Koek and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 84-94; DOI: https://doi.org/10.1124/jpet.116.237305

  5. Goulet, Lance

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  6. Greig, Gerard

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

  7. Griffith, L. G.

    1. Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      Open Access
      Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495

  8. Guerini, Elena

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

H

  1. Hao, Junliang

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  2. Harada, Akina

    1. TAK-063, a Novel Phosphodiesterase 10A Inhibitor, Protects from Striatal Neurodegeneration and Ameliorates Behavioral Deficits in the R6/2 Mouse Model of Huntington’s Disease
      Akina Harada, Kazunori Suzuki and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 75-83; DOI: https://doi.org/10.1124/jpet.116.237388

  3. Harwood, Benjamin N.

    1. Mutation-Induced Functional Alterations of CCR6
      Bina Julian, Kevin Gao, Benjamin N. Harwood, Martin Beinborn and Alan S. Kopin
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 106-116; DOI: https://doi.org/10.1124/jpet.116.237669

  4. Hedehus, Maj

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  5. Heinz, Beverly A.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  6. Hellman, Sarah L.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  7. Hong, Jie

    1. Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett’s Associated Esophageal Adenocarcinoma Cells
      Dan Li, Jie Hong and Weibiao Cao
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 14-22; DOI: https://doi.org/10.1124/jpet.116.236620

  8. Huang, Fei

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  9. Hughes, D. J.

    1. Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      Open Access
      Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495

  10. Hutchinson, John H.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

I

  1. Imai, Azusa

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  2. Inoue, Katsuhisa

    1. Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
      Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984

  3. Ito, Yoshihiko

    1. Urinary Excretion Contributes to Long-Lasting Blockade of Bladder Muscarinic Receptors by Imidafenacin: Effect of Bilateral Ureteral Ligation
      Yoshihiko Ito, Shiori Kuraoka, Soma Endo, Ayaka Takahashi, Satomi Onoue and Shizuo Yamada
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 69-74; DOI: https://doi.org/10.1124/jpet.116.236497

  4. Iwata, Kazumi

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  5. Iyer, Abishek

    1. An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice
      Anh Do, Robert C. Reid, Rink-Jan Lohman, Matthew J. Sweet, David P. Fairlie and Abishek Iyer
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 140-151; DOI: https://doi.org/10.1124/jpet.116.236711

J

  1. Janowsky, Aaron

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  2. Johnson, Adam R.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  3. Johnson, Robert A.

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  4. Julian, Bina

    1. Mutation-Induced Functional Alterations of CCR6
      Bina Julian, Kevin Gao, Benjamin N. Harwood, Martin Beinborn and Alan S. Kopin
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 106-116; DOI: https://doi.org/10.1124/jpet.116.237669

K

  1. Kanagasabai, Ragu

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  2. Karmahapatra, Soumendrakrishna

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  3. Katewa, Arna

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  4. Kato, Shinichi

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  5. Kientz, Corey A.

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  6. Kim, Sunyoung O.

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  7. Kimura, Haruhide

    1. TAK-063, a Novel Phosphodiesterase 10A Inhibitor, Protects from Striatal Neurodegeneration and Ameliorates Behavioral Deficits in the R6/2 Mouse Model of Huntington’s Disease
      Akina Harada, Kazunori Suzuki and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 75-83; DOI: https://doi.org/10.1124/jpet.116.237388

  8. King, Christopher D.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  9. Knopp, Kelly L.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  10. Koek, Wouter

    1. Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Nathan C. Mitchell, Melodi A. Bowman, Georgianna G. Gould, Wouter Koek and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 84-94; DOI: https://doi.org/10.1124/jpet.116.237305

  11. Kopin, Alan S.

    1. Mutation-Induced Functional Alterations of CCR6
      Bina Julian, Kevin Gao, Benjamin N. Harwood, Martin Beinborn and Alan S. Kopin
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 106-116; DOI: https://doi.org/10.1124/jpet.116.237669

  12. Kostrzewski, T.

    1. Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      Open Access
      Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495

  13. Krishnan, Jishnu K. S.

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

  14. Krushinski, Joseph H.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  15. Kuraoka, Shiori

    1. Urinary Excretion Contributes to Long-Lasting Blockade of Bladder Muscarinic Receptors by Imidafenacin: Effect of Bilateral Ureteral Ligation
      Yoshihiko Ito, Shiori Kuraoka, Soma Endo, Ayaka Takahashi, Satomi Onoue and Shizuo Yamada
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 69-74; DOI: https://doi.org/10.1124/jpet.116.236497

L

  1. Lai, Andiliy

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  2. Lai, Yurong

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  3. Le, Yuan

    1. Hormonal and Chemical Regulation of the Glut9 Transporter in Mice
      Pengli Bu, Yuan Le, Yue Zhang and Xingguo Cheng
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 206-214; DOI: https://doi.org/10.1124/jpet.116.237040

  4. Lewin-Koh, Sock-Cheng

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  5. Li, Albert P.

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  6. Li, Dan

    1. Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett’s Associated Esophageal Adenocarcinoma Cells
      Dan Li, Jie Hong and Weibiao Cao
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 14-22; DOI: https://doi.org/10.1124/jpet.116.236620

  7. Liu, Lichuan

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  8. Lohman, Rink-Jan

    1. An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice
      Anh Do, Robert C. Reid, Rink-Jan Lohman, Matthew J. Sweet, David P. Fairlie and Abishek Iyer
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 140-151; DOI: https://doi.org/10.1124/jpet.116.236711

  9. Lonergan, Dave

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  10. Lucaites, Virginia L.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

M

  1. Ma, Gina L.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  2. Mallalieu, Navita L.

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

  3. Maren, Deanna L.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  4. Matsumoto, Misaki

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  5. McDowell, Michelle

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  6. Menezes, Michelle M.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  7. Miller, Steven L.

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

  8. Mimura, Yoshihisa

    1. Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
      Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984

  9. Misner, Dinah L.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  10. Mitchell, Nathan C.

    1. Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice
      Nathan C. Mitchell, Melodi A. Bowman, Georgianna G. Gould, Wouter Koek and Lynette C. Daws
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 84-94; DOI: https://doi.org/10.1124/jpet.116.237305

  11. Morad, Martin

    1. Xanthohumol Modulates Calcium Signaling in Rat Ventricular Myocytes: Possible Antiarrhythmic Properties
      Juan Jose Arnaiz-Cot, Lars Cleemann and Martin Morad
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 239-248; DOI: https://doi.org/10.1124/jpet.116.236588

  12. Morin, S. Michelle

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

N

  1. Nakamura, Akio

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  2. Nelson, David L.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  3. Ng, Lindsay

    1. Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture
      Liting Deng, Lindsay Ng, Tatsuya Ozawa and Nephi Stella
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 215-224; DOI: https://doi.org/10.1124/jpet.116.236968

O

  1. Ohta, Kinya

    1. Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
      Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984

  2. Okun, Ilya

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  3. Onoue, Satomi

    1. Urinary Excretion Contributes to Long-Lasting Blockade of Bladder Muscarinic Receptors by Imidafenacin: Effect of Bilateral Ureteral Ligation
      Yoshihiko Ito, Shiori Kuraoka, Soma Endo, Ayaka Takahashi, Satomi Onoue and Shizuo Yamada
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 69-74; DOI: https://doi.org/10.1124/jpet.116.236497

  4. Ozawa, Tatsuya

    1. Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture
      Liting Deng, Lindsay Ng, Tatsuya Ozawa and Nephi Stella
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 215-224; DOI: https://doi.org/10.1124/jpet.116.236968

P

  1. Pang, K. Sandy

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  2. Parrott, Neil

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

  3. Pidoplichko, Volodymyr I.

    1. The M1 Muscarinic Receptor Antagonist VU0255035 Delays the Development of Status Epilepticus after Organophosphate Exposure and Prevents Hyperexcitability in the Basolateral Amygdala
      Steven L. Miller, Vassiliki Aroniadou-Anderjaska, Volodymyr I. Pidoplichko, Taiza H. Figueiredo, James P. Apland, Jishnu K. S. Krishnan and Maria F. M. Braga
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 23-32; DOI: https://doi.org/10.1124/jpet.116.236125

  4. Pillai, Anilkumar

    1. Estrogen Signaling as a Therapeutic Target in Neurodevelopmental Disorders
      Amanda Crider and Anilkumar Pillai
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 48-58; DOI: https://doi.org/10.1124/jpet.116.237412

  5. Prasad, Bhagwat

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  6. Prodanovich, Patricia

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

Q

  1. Qiu, NaHong

    1. Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non–Michaelis-Menten P450 Kinetics on Fraction Metabolized
      Stephen Fowler, Elena Guerini, NaHong Qiu, Yumi Cleary, Neil Parrott, Gerard Greig and Navita L. Mallalieu
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 164-173; DOI: https://doi.org/10.1124/jpet.116.237214

  2. Quach, Holly P.

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

R

  1. Reed, John F.

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  2. Reid, Robert C.

    1. An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice
      Anh Do, Robert C. Reid, Rink-Jan Lohman, Matthew J. Sweet, David P. Fairlie and Abishek Iyer
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 140-151; DOI: https://doi.org/10.1124/jpet.116.236711

  3. Reif, Karin

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  4. Reinhard, Matthew R.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  5. Ritke, Mary K.

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  6. Rogovoy, Borys

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  7. Ross, Jed

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

S

  1. Salim, Samina

    1. Oxidative Stress and the Central Nervous System
      Samina Salim
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 201-205; DOI: https://doi.org/10.1124/jpet.116.237503

  2. Santini, Angelina M.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  3. Schaus, John M.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  4. Schuetz, Erin G.

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  5. Schutt, Leah K.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  6. Serdar, Lucas

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  7. Shannon, Kristen E.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  8. Shimada, Yuki

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  9. Silva, Jose

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  10. Staflin, Karin

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  11. Stapleton, Patricia

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  12. Statnick, Michael A.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  13. Stein, Adam J.

    1. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis
      Gretchen Bain, Kristen E. Shannon, Fei Huang, Janice Darlington, Lance Goulet, Patricia Prodanovich, Gina L. Ma, Angelina M. Santini, Adam J. Stein, Dave Lonergan, Christopher D. King, Imelda Calderon, Andiliy Lai, John H. Hutchinson and Jilly F. Evans
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 1-13; DOI: https://doi.org/10.1124/jpet.116.237156

  14. Stella, Nephi

    1. Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture
      Liting Deng, Lindsay Ng, Tatsuya Ozawa and Nephi Stella
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 215-224; DOI: https://doi.org/10.1124/jpet.116.236968

  15. Stokes, C. L.

    1. Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      Open Access
      Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495

  16. Suter, Todd M.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  17. Suzuki, Kazunori

    1. TAK-063, a Novel Phosphodiesterase 10A Inhibitor, Protects from Striatal Neurodegeneration and Ameliorates Behavioral Deficits in the R6/2 Mouse Model of Huntington’s Disease
      Akina Harada, Kazunori Suzuki and Haruhide Kimura
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 75-83; DOI: https://doi.org/10.1124/jpet.116.237388

  18. Svensson, Kjell A.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  19. Swanson, Tracy

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  20. Sweet, Matthew J.

    1. An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice
      Anh Do, Robert C. Reid, Rink-Jan Lohman, Matthew J. Sweet, David P. Fairlie and Abishek Iyer
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 140-151; DOI: https://doi.org/10.1124/jpet.116.236711

T

  1. Takahashi, Ayaka

    1. Urinary Excretion Contributes to Long-Lasting Blockade of Bladder Muscarinic Receptors by Imidafenacin: Effect of Bilateral Ureteral Ligation
      Yoshihiko Ito, Shiori Kuraoka, Soma Endo, Ayaka Takahashi, Satomi Onoue and Shizuo Yamada
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 69-74; DOI: https://doi.org/10.1124/jpet.116.236497

  2. Tanner, Julie-Anne

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  3. Tarrant, Jacqueline M.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  4. Thummel, Kenneth E.

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

  5. Tirona, Rommel G.

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  6. Tsamandouras, N.

    1. Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      Open Access
      Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System
      N. Tsamandouras, T. Kostrzewski, C. L. Stokes, L. G. Griffith, D. J. Hughes and M. Cirit
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 95-105; DOI: https://doi.org/10.1124/jpet.116.237495

  7. Tsukahara, Takuya

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  8. Tsuzuki, Ayaka

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  9. Tyndale, Rachel F.

    1. Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors
      Julie-Anne Tanner, Bhagwat Prasad, Katrina G. Claw, Patricia Stapleton, Amarjit Chaudhry, Erin G. Schuetz, Kenneth E. Thummel and Rachel F. Tyndale
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 129-139; DOI: https://doi.org/10.1124/jpet.116.237594

U

  1. Utsumi, Daichi

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

W

  1. Wang, Jason Z. Y.

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  2. Wang, Xushan

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  3. Wiernicki, Todd R.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  4. Wolfrum, Katherine M.

    1. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
      Amy J. Eshleman, Katherine M. Wolfrum, John F. Reed, Sunyoung O. Kim, Tracy Swanson, Robert A. Johnson and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 33-47; DOI: https://doi.org/10.1124/jpet.116.236349

  5. Wong, Harvey

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  6. Wright, Rebecca A.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

Y

  1. Yabe-Nishimura, Chihiro

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  2. Yalowich, Jack C.

    1. Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform
      Ragu Kanagasabai, Lucas Serdar, Soumendrakrishna Karmahapatra, Corey A. Kientz, Justin Ellis, Mary K. Ritke, Terry S. Elton and Jack C. Yalowich
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 152-163; DOI: https://doi.org/10.1124/jpet.116.237107

  3. Yamada, Shizuo

    1. Urinary Excretion Contributes to Long-Lasting Blockade of Bladder Muscarinic Receptors by Imidafenacin: Effect of Bilateral Ureteral Ligation
      Yoshihiko Ito, Shiori Kuraoka, Soma Endo, Ayaka Takahashi, Satomi Onoue and Shizuo Yamada
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 69-74; DOI: https://doi.org/10.1124/jpet.116.236497

  4. Yang, Charles R.

    1. Open Access
      An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis
      Kjell A. Svensson, Beverly A. Heinz, John M. Schaus, James P. Beck, Junliang Hao, Joseph H. Krushinski, Matthew R. Reinhard, Michael P. Cohen, Sarah L. Hellman, Brian G. Getman, Xushan Wang, Michelle M. Menezes, Deanna L. Maren, Julie F. Falcone, Wesley H. Anderson, Rebecca A. Wright, S. Michelle Morin, Kelly L. Knopp, Benjamin L. Adams, Borys Rogovoy, Ilya Okun, Todd M. Suter, Michael A. Statnick, Donald R. Gehlert, David L. Nelson, Virginia L. Lucaites, Renee Emkey, Neil W. DeLapp, Todd R. Wiernicki, Jeffrey W. Cramer, Charles R. Yang and Robert F. Bruns
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 117-128; DOI: https://doi.org/10.1124/jpet.116.236372

  5. Yasujima, Tomoya

    1. Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
      Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984

  6. Yokota, Haruka

    1. NOX1/NADPH Oxidase Expressed in Colonic Macrophages Contributes to the Pathogenesis of Colonic Inflammation in Trinitrobenzene Sulfonic Acid–Induced Murine Colitis
      Haruka Yokota, Ayaka Tsuzuki, Yuki Shimada, Azusa Imai, Daichi Utsumi, Takuya Tsukahara, Misaki Matsumoto, Kikuko Amagase, Kazumi Iwata, Akio Nakamura, Chihiro Yabe-Nishimura and Shinichi Kato
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 192-200; DOI: https://doi.org/10.1124/jpet.116.235580

  7. Young, Wendy B.

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  8. Yuasa, Hiroaki

    1. Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase
      Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa Mimura and Hiroaki Yuasa
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 59-68; DOI: https://doi.org/10.1124/jpet.116.236984

Z

  1. Zhang, Yue

    1. Hormonal and Chemical Regulation of the Glut9 Transporter in Mice
      Pengli Bu, Yuan Le, Yue Zhang and Xingguo Cheng
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 206-214; DOI: https://doi.org/10.1124/jpet.116.237040

  2. Zhang, Yueping

    1. Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
      Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai and K. Sandy Pang
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 174-191; DOI: https://doi.org/10.1124/jpet.116.236935

  3. Zhong, Fiona

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224

  4. Zhong, Shelly

    1. Bruton’s Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats
      Rebecca I. Erickson, Leah K. Schutt, Jacqueline M. Tarrant, Michelle McDowell, Lichuan Liu, Adam R. Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A. D. Carano, Karin Staflin, Fiona Zhong, James J. Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy B. Young, Donna M. Dambach and Dinah L. Misner
      Journal of Pharmacology and Experimental Therapeutics January 2017, 360 (1) 226-238; DOI: https://doi.org/10.1124/jpet.116.236224
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