Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn
Research ArticleDrug Discovery and Translational Medicine

Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy

Mark R. Kelley, James H. Wikel, Chunlu Guo, Karen E. Pollok, Barbara J. Bailey, Randy Wireman, Melissa L. Fishel and Michael R. Vasko
Journal of Pharmacology and Experimental Therapeutics November 2016, 359 (2) 300-309; DOI: https://doi.org/10.1124/jpet.116.235283
Mark R. Kelley
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James H. Wikel
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chunlu Guo
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karen E. Pollok
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Barbara J. Bailey
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Randy Wireman
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Melissa L. Fishel
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael R. Vasko
Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Information

vol. 359 no. 2 300-309
DOI 
https://doi.org/10.1124/jpet.116.235283
PubMed 
27608656

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 19, 2016
  • Accepted September 2, 2016
  • Published online October 7, 2016.

Article Versions

  • Earlier version (September 8, 2016 - 08:41).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mark R. Kelley,
  2. James H. Wikel,
  3. Chunlu Guo,
  4. Karen E. Pollok,
  5. Barbara J. Bailey,
  6. Randy Wireman,
  7. Melissa L. Fishel, and
  8. Michael R. Vasko
  1. Department of Pediatrics, Herman B Wells Center for Pediatric Research (M.R.K., J.H.W., K.E.P., B.J.B., R.W., M.L.F.), and Department of Pharmacology and Toxicology (M.R.K., C.G., K.E.P.,M.L.F., M.R.V.), Indiana University School of Medicine, Indianapolis, Indiana; and ApeX Therapeutics, Indianapolis, Indiana (J.H.W.)
  1. Address correspondence to:
    Dr. Mark R. Kelley, Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut, R4 302, Indianapolis, IN 46202. E-mail: mkelley{at}iupui.edu
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: September 2016 to February 2021

AbstractFullPdf
Sep 20162442183
Oct 20162054651
Nov 2016942428
Dec 2016501816
Jan 2017471413
Feb 2017572015
Mar 2017462227
Apr 201734618
May 2017251314
Jun 20173295
Jul 20172658
Aug 201729118
Sep 20174579
Oct 2017183621
Nov 20176264
Dec 201741812
Jan 20187238
Feb 201802114
Mar 2018186
Apr 201812714
May 20181158
Jun 201821610
Jul 20182123
Aug 20180186
Sep 201812511
Oct 2018284
Nov 20180147
Dec 20180139
Jan 2019063
Feb 20191199
Mar 201901918
Apr 201901521
May 201921513
Jun 201922423
Jul 201901712
Aug 201912012
Sep 201912120
Oct 201912026
Nov 201912210
Dec 201911815
Jan 20201168
Feb 20200138
Mar 202032915
Apr 20200168
May 20200148
Jun 202001515
Jul 20200207
Aug 2020492
Sep 2020254
Oct 202001813
Nov 202021519
Dec 202042023
Jan 202131723
Feb 20212919

PreviousNext
Back to top

In this issue

Journal of Pharmacology and Experimental Therapeutics: 359 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 359, Issue 2
1 Nov 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Journal of Pharmacology and Experimental Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy
(Your Name) has forwarded a page to you from Journal of Pharmacology and Experimental Therapeutics
(Your Name) thought you would be interested in this article in Journal of Pharmacology and Experimental Therapeutics.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleDrug Discovery and Translational Medicine

Targeting APE1 for Prevention of CIPN

Mark R. Kelley, James H. Wikel, Chunlu Guo, Karen E. Pollok, Barbara J. Bailey, Randy Wireman, Melissa L. Fishel and Michael R. Vasko
Journal of Pharmacology and Experimental Therapeutics November 1, 2016, 359 (2) 300-309; DOI: https://doi.org/10.1124/jpet.116.235283

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Research ArticleDrug Discovery and Translational Medicine

Targeting APE1 for Prevention of CIPN

Mark R. Kelley, James H. Wikel, Chunlu Guo, Karen E. Pollok, Barbara J. Bailey, Randy Wireman, Melissa L. Fishel and Michael R. Vasko
Journal of Pharmacology and Experimental Therapeutics November 1, 2016, 359 (2) 300-309; DOI: https://doi.org/10.1124/jpet.116.235283
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • IKCa Channels in Muscle Hypertrophy
  • Cx43 Activity and Modulation in the Myometrium
  • Angptl3 siRNA Treatment of Nephrotic Syndrome
Show more Drug Discovery and Translational Medicine

Similar Articles

  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics