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Index by author

September 01, 2016; Volume 358,Issue 3

A

  1. Afzelius, Lovisa

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  2. Ahlgren, Charlotte

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  3. Akama, Tsutomu

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  4. Al-Khrasani, Mahmoud

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  5. Albright, Charles F.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  6. Alkharfy, Khalid M.

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  7. Allen, Jason

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  8. Ameriks, Michael K.

    1. Reply to “A Comment on ‘Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8’”
      Michael P. Maher, Michael K. Ameriks, Brad M. Savall, Nicholas I. Carruthers and Timothy W. Lovenberg
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 527; DOI: https://doi.org/10.1124/jpet.116.234815

  9. Andreadou, Ioanna

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  10. Arai, Kiyoshi

    1. CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats
      Kiyoshi Arai, Yuka Morikawa, Naoko Ubukata, Hiroyuki Tsuruoka and Tsuyoshi Homma
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 548-557; DOI: https://doi.org/10.1124/jpet.116.234765

  11. Arkles, Jeffery S.

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

B

  1. Baia, Diogo

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  2. Baker, Kevin

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  3. Balakrishnan, Anand

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Baltazar, Grober

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  5. Berretta, Remus

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  6. Berry, David B.

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  7. Bhardwaj, Sumita

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  8. Bi, Yingzhi

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  9. Bibli, Sofia-Iris

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  10. Bourin, Clotilde

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  11. Bristow, Linda

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  12. Bronson, Joanne

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  13. Brown, Jeffrey M.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  14. Budac, David

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

C

  1. Cajina, Manuel

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  2. Carruthers, Nicholas I.

    1. Reply to “A Comment on ‘Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8’”
      Michael P. Maher, Michael K. Ameriks, Brad M. Savall, Nicholas I. Carruthers and Timothy W. Lovenberg
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 527; DOI: https://doi.org/10.1124/jpet.116.234815

  3. Carson, Ken

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Chacko, Geena

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  5. Chatzianastasiou, Athanasia

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  6. Chen, Zhengju

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  7. Cheng, Yaofeng

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  8. Chiba, Kenji

    1. Involvement of Neuroinflammation during Brain Development in Social Cognitive Deficits in Autism Spectrum Disorder and Schizophrenia
      Yutaka Nakagawa and Kenji Chiba
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 504-515; DOI: https://doi.org/10.1124/jpet.116.234476

  9. Chu, Lin

    1. Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
      Xueping Zhou, Weizhen Wu, Lin Chu, David E. Gutstein, Dietmar Seiffert and Xinkang Wang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 405-412; DOI: https://doi.org/10.1124/jpet.116.234575

  10. Classon, Björn

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  11. Cloutier, Michelle M.

    1. Acetaminophen Attenuates House Dust Mite–Induced Allergic Airway Disease in Mice
      Gregory J. Smith, Roger S. Thrall, Michelle M. Cloutier, Jose E. Manautou and John B. Morris
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 569-579; DOI: https://doi.org/10.1124/jpet.116.233684

  12. Condello, Carlo

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  13. Conway, Charles M.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  14. Copper, Joshua M.

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

D

  1. Dai, Jun

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  2. Daiber, Andreas

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  3. Dandapani, Kumaran

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Das, Hriday K.

    1. The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal
      Marianna E. Jung, Daniel B. Metzger and Hriday K. Das
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 516-526; DOI: https://doi.org/10.1124/jpet.116.233361

  5. Das, Manish Lal

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  6. Date, Onkar

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  7. Dee, Joshua

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  8. de Miguel, Irene

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  9. Denton, Rex

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  10. Detremmerie, Charlotte M.

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  11. Di Lisa, Fabio

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  12. Dokania, Manoj

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  13. Dong, Chen

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  14. Dotimas, Hyna

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

  15. Dugger, Brittany N.

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  16. Dzierba, Carolyn

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

E

  1. Easton, Amy

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  2. Edenius, Charlotte

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  3. Efentakis, Panagiotis

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  4. Elavazhagan, Saravanan

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  5. Elepano, Manuel

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

F

  1. Farde, Lars

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  2. Farnham, Melissa M. J.

    1. Intrathecal Intermittent Orexin-A Causes Sympathetic Long-Term Facilitation and Sensitizes the Peripheral Chemoreceptor Response to Hypoxia in Rats
      Seung Jae Kim, Paul M. Pilowsky and Melissa M. J. Farnham
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 492-501; DOI: https://doi.org/10.1124/jpet.116.234443

  3. Fehér, Ágnes

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  4. Feng, Jianlin

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  5. Franco, Rafael

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  6. Franklin, Cynthia

    1. A Novel Model of Dexamethasone-Induced Hypertension: Use in Investigating the Role of Tyrosine Hydroxylase
      Alexandra E. Soto-Piña, Cynthia Franklin, C.S. Sheela Rani, Helmut Gottlieb, Carmen Hinojosa-Laborde and Randy Strong
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 528-536; DOI: https://doi.org/10.1124/jpet.116.234005

  7. Franti, Michael

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

G

  1. Gao, Yuansheng

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  2. Gardinier, Kevin M.

    1. A Comment on “Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8”
      Jeffrey M. Witkin and Kevin M. Gardinier
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 502-503; DOI: https://doi.org/10.1124/jpet.116.234419

  3. Gaud, Nilesh

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  4. Giles, Kurt

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  5. Gottlieb, Helmut

    1. A Novel Model of Dexamethasone-Induced Hypertension: Use in Investigating the Role of Tyrosine Hydroxylase
      Alexandra E. Soto-Piña, Cynthia Franklin, C.S. Sheela Rani, Helmut Gottlieb, Carmen Hinojosa-Laborde and Randy Strong
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 528-536; DOI: https://doi.org/10.1124/jpet.116.234005

  6. Grabowska, Urszula

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  7. Grace, James E.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  8. Gruber, Susanne

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  9. Guan, Shenheng

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  10. Gulianello, Michael

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  11. Gupta, Priyanka

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

  12. Gutstein, David E.

    1. Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
      Xueping Zhou, Weizhen Wu, Lin Chu, David E. Gutstein, Dietmar Seiffert and Xinkang Wang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 405-412; DOI: https://doi.org/10.1124/jpet.116.234575

  13. Gyires, Klára

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

H

  1. Haddjeri, Nasser

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  2. Halldin, Christer

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  3. Hamman, Brian D.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Hara, Atsuko

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  5. Harada, Tatsuhiko

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  6. Hayes, David B.

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

  7. He, Shufang

    1. Spinal Neuronal NOS Signaling Contributes to Morphine Cardioprotection in Ischemia Reperfusion Injury in Rats
      Lingling Jiang, Jun Hu, Shufang He, Li Zhang and Ye Zhang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 450-456; DOI: https://doi.org/10.1124/jpet.116.234021

  8. Hein, Lutz

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  9. Helyes, Zsuzsanna

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  10. Henderson, Ian

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  11. Hewitt, Ellen

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  12. Hillhouse, Todd M.

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  13. Hinojosa-Laborde, Carmen

    1. A Novel Model of Dexamethasone-Induced Hypertension: Use in Investigating the Role of Tyrosine Hydroxylase
      Alexandra E. Soto-Piña, Cynthia Franklin, C.S. Sheela Rani, Helmut Gottlieb, Carmen Hinojosa-Laborde and Randy Strong
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 528-536; DOI: https://doi.org/10.1124/jpet.116.234005

  14. Holenarsipur, Vinay K.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333
    2. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  15. Holten, John

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  16. Holzer, Peter

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  17. Homma, Tsuyoshi

    1. CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats
      Kiyoshi Arai, Yuka Morikawa, Naoko Ubukata, Hiroyuki Tsuruoka and Tsuyoshi Homma
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 548-557; DOI: https://doi.org/10.1124/jpet.116.234765

  18. Houser, Steven R.

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  19. Hu, Jun

    1. Spinal Neuronal NOS Signaling Contributes to Morphine Cardioprotection in Ischemia Reperfusion Injury in Rats
      Lingling Jiang, Jun Hu, Shufang He, Li Zhang and Ye Zhang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 450-456; DOI: https://doi.org/10.1124/jpet.116.234021

  20. Huang, Jianhe

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  21. Huang, Yanling

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  22. Humphreys, William G.

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

I

  1. Ishimatsu, Yuji

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  2. Izumikawa, Koichi

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

J

  1. Jadiya, Pooja

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  2. Jarnagin, Kurt

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  3. Jerning, Eva

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  4. Jiang, Lingling

    1. Spinal Neuronal NOS Signaling Contributes to Morphine Cardioprotection in Ischemia Reperfusion Injury in Rats
      Lingling Jiang, Jun Hu, Shufang He, Li Zhang and Ye Zhang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 450-456; DOI: https://doi.org/10.1124/jpet.116.234021

  5. Johnström, Peter

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  6. Jones-Iatauro, Shannon

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  7. Jung, Marianna E.

    1. The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal
      Marianna E. Jung, Daniel B. Metzger and Hriday K. Das
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 516-526; DOI: https://doi.org/10.1124/jpet.116.233361

  8. Juréus, Anders

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

K

  1. Kahn, Julius

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

  2. Kakugawa, Tomoyuki

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  3. Kaludercic, Nina

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  4. Khalil, Ashraf M.

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

  5. Kim, Seung Jae

    1. Intrathecal Intermittent Orexin-A Causes Sympathetic Long-Term Facilitation and Sensitizes the Peripheral Chemoreceptor Response to Hypoxia in Rats
      Seung Jae Kim, Paul M. Pilowsky and Melissa M. J. Farnham
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 492-501; DOI: https://doi.org/10.1124/jpet.116.234443

  6. Kiss, Laszlo

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  7. Kohno, Shigeru

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  8. Kosai, Kosuke

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  9. Kostich, Walter

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  10. Kozsurek, Márk

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  11. Kumar, Anoop

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

L

  1. LaCanna, Ryan

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  2. Lai, Yurong

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  3. Lamerdin, Jane E.

    1. Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors
      Ashraf M. Khalil, Hyna Dotimas, Julius Kahn, Jane E. Lamerdin, David B. Hayes, Priyanka Gupta and Michael Franti
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 423-430; DOI: https://doi.org/10.1124/jpet.116.232322

  4. Lanciego, José L.

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  5. Langish, Robert

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  6. Lanthorn, Thomas H.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  7. Lentz, Kimberley A.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  8. Leung, Susan W.S.

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  9. Lewis, Martin

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  10. Li, Yu-Wen

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  11. Li, Zhe

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  12. Li, Zhuoming

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  13. Lindström, Erik

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  14. Lippy, Jonathan

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  15. Liu, Fang

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  16. Louis, Justin V.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  17. Lovenberg, Timothy W.

    1. Reply to “A Comment on ‘Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8’”
      Michael P. Maher, Michael K. Ameriks, Brad M. Savall, Nicholas I. Carruthers and Timothy W. Lovenberg
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 527; DOI: https://doi.org/10.1124/jpet.116.234815

  18. Lu, Yifeng

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

M

  1. Macor, John E.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  2. Maher, Michael P.

    1. Reply to “A Comment on ‘Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8’”
      Michael P. Maher, Michael K. Ameriks, Brad M. Savall, Nicholas I. Carruthers and Timothy W. Lovenberg
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 527; DOI: https://doi.org/10.1124/jpet.116.234815

  3. Main, Alan

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Mak, Yvonne

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  5. Malcangio, Marzia

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  6. Malmborg, Jonas

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  7. Manautou, Jose E.

    1. Acetaminophen Attenuates House Dust Mite–Induced Allergic Airway Disease in Mice
      Gregory J. Smith, Roger S. Thrall, Michelle M. Cloutier, Jose E. Manautou and John B. Morris
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 569-579; DOI: https://doi.org/10.1124/jpet.116.233684

  8. Mandlekar, Sandhya

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333
    2. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  9. Manolopoulos, Vangelis G.

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  10. Marathe, Punit

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  11. Martin, Shamra

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  12. Martínez-Pinilla, Eva

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  13. Meewan, Maliwan

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  14. Metzger, Daniel B.

    1. The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal
      Marianna E. Jung, Daniel B. Metzger and Hriday K. Das
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 516-526; DOI: https://doi.org/10.1124/jpet.116.233361

  15. Molski, Ted

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  16. Morikawa, Yuka

    1. CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats
      Kiyoshi Arai, Yuka Morikawa, Naoko Ubukata, Hiroyuki Tsuruoka and Tsuyoshi Homma
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 548-557; DOI: https://doi.org/10.1124/jpet.116.234765

  17. Morita, Towako

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  18. Mørk, Arne

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  19. Morris, John B.

    1. Acetaminophen Attenuates House Dust Mite–Induced Allergic Airway Disease in Mice
      Gregory J. Smith, Roger S. Thrall, Michelle M. Cloutier, Jose E. Manautou and John B. Morris
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 569-579; DOI: https://doi.org/10.1124/jpet.116.233684

  20. Mukae, Hiroshi

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  21. Murugesan, Senthilkumar

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

N

  1. Naidu, Sreenivasulu

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  2. Nakagawa, Yutaka

    1. Involvement of Neuroinflammation during Brain Development in Social Cognitive Deficits in Autism Spectrum Disorder and Schizophrenia
      Yutaka Nakagawa and Kenji Chiba
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 504-515; DOI: https://doi.org/10.1124/jpet.116.234476

  3. Nakashima, Shota

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  4. Nara, Susheel J.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  5. Navarro, Gemma

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  6. Nouraldeen, Amr

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

O

  1. O’Malley, Kevin

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  2. Oehler, Abby

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  3. Olson, Steven H.

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  4. Oyarzabal, Julen

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

P

  1. Papapetropoulos, Andreas

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  2. Patel, Vickas V.

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  3. Pehrson, Alan L.

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  4. Pieschl, Rick

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  5. Pilowsky, Paul M.

    1. Intrathecal Intermittent Orexin-A Causes Sympathetic Long-Term Facilitation and Sensitizes the Peripheral Chemoreceptor Response to Hypoxia in Rats
      Seung Jae Kim, Paul M. Pilowsky and Melissa M. J. Farnham
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 492-501; DOI: https://doi.org/10.1124/jpet.116.234443

  6. Pitcher, Thomas

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  7. Porter, Joseph H.

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  8. Powers, Jeffery C.

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  9. Prusiner, Stanley B.

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  10. Puskár, Zita

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

R

  1. Rabal, Obdulia

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  2. Rajanna, Prabhakar

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  3. Rani, C.S. Sheela

    1. A Novel Model of Dexamethasone-Induced Hypertension: Use in Investigating the Role of Tyrosine Hydroxylase
      Alexandra E. Soto-Piña, Cynthia Franklin, C.S. Sheela Rani, Helmut Gottlieb, Carmen Hinojosa-Laborde and Randy Strong
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 528-536; DOI: https://doi.org/10.1124/jpet.116.234005

  4. Recchia, Fabio A.

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  5. Reyes-Resina, Irene

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  6. Rizoska, Biljana

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  7. Rock, Fernando

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  8. Rovera, Renaud

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

S

  1. Sahlberg, Britt-Louise

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

  2. Sakamoto, Noriho

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932

  3. Sanchez, Connie

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  4. Sánchez-Arias, Juan A.

    1. Two Affinity Sites of the Cannabinoid Subtype 2 Receptor Identified by a Novel Homogeneous Binding Assay
      Eva Martínez-Pinilla, Obdulia Rabal, Irene Reyes-Resina, Marta Zamarbide, Gemma Navarro, Juan A. Sánchez-Arias, Irene de Miguel, José L. Lanciego, Julen Oyarzabal and Rafael Franco
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 580-587; DOI: https://doi.org/10.1124/jpet.116.234948

  5. Santone, Kenneth S.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  6. Savall, Brad M.

    1. Reply to “A Comment on ‘Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8’”
      Michael P. Maher, Michael K. Ameriks, Brad M. Savall, Nicholas I. Carruthers and Timothy W. Lovenberg
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 527; DOI: https://doi.org/10.1124/jpet.116.234815

  7. Savelieva, Katerina

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  8. Schött, Pär

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  9. Schou, Magnus

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  10. Seiffert, Dietmar

    1. Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
      Xueping Zhou, Weizhen Wu, Lin Chu, David E. Gutstein, Dietmar Seiffert and Xinkang Wang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 405-412; DOI: https://doi.org/10.1124/jpet.116.234575

  11. Seki, Mitsuru

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  12. Selvam, Sabariya

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  13. Sexton, Holly

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  14. Shankar, Ganesh

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  15. Sharma, Vivek

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  16. Shen, Hong

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  17. Shipkova, Petia

    1. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition
      Yurong Lai, Sandhya Mandlekar, Hong Shen, Vinay K. Holenarsipur, Robert Langish, Prabhakar Rajanna, Senthilkumar Murugesan, Nilesh Gaud, Sabariya Selvam, Onkar Date, Yaofeng Cheng, Petia Shipkova, Jun Dai, William G. Humphreys and Punit Marathe
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 397-404; DOI: https://doi.org/10.1124/jpet.116.234914

  18. Silber, B. Michael

    1. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice
      Kurt Giles, David B. Berry, Carlo Condello, Brittany N. Dugger, Zhe Li, Abby Oehler, Sumita Bhardwaj, Manuel Elepano, Shenheng Guan, B. Michael Silber, Steven H. Olson and Stanley B. Prusiner
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 537-547; DOI: https://doi.org/10.1124/jpet.116.235556

  19. Smagin, Gennady

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  20. Smith, Gregory J.

    1. Acetaminophen Attenuates House Dust Mite–Induced Allergic Airway Disease in Mice
      Gregory J. Smith, Roger S. Thrall, Michelle M. Cloutier, Jose E. Manautou and John B. Morris
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 569-579; DOI: https://doi.org/10.1124/jpet.116.233684

  21. Song, Dekun

    1. Open Access
      Task- and Treatment Length–Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
      Alan L. Pehrson, Todd M. Hillhouse, Nasser Haddjeri, Renaud Rovera, Joseph H. Porter, Arne Mørk, Gennady Smagin, Dekun Song, David Budac, Manuel Cajina and Connie Sanchez
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 472-482; DOI: https://doi.org/10.1124/jpet.116.233924

  22. Soto-Piña, Alexandra E.

    1. A Novel Model of Dexamethasone-Induced Hypertension: Use in Investigating the Role of Tyrosine Hydroxylase
      Alexandra E. Soto-Piña, Cynthia Franklin, C.S. Sheela Rani, Helmut Gottlieb, Carmen Hinojosa-Laborde and Randy Strong
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 528-536; DOI: https://doi.org/10.1124/jpet.116.234005

  23. Strong, Randy

    1. A Novel Model of Dexamethasone-Induced Hypertension: Use in Investigating the Role of Tyrosine Hydroxylase
      Alexandra E. Soto-Piña, Cynthia Franklin, C.S. Sheela Rani, Helmut Gottlieb, Carmen Hinojosa-Laborde and Randy Strong
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 528-536; DOI: https://doi.org/10.1124/jpet.116.234005

  24. Swaffield, Jon

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  25. Szabó, Csaba

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

T

  1. Tábi, Tamás

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  2. Thrall, Roger S.

    1. Acetaminophen Attenuates House Dust Mite–Induced Allergic Airway Disease in Mice
      Gregory J. Smith, Roger S. Thrall, Michelle M. Cloutier, Jose E. Manautou and John B. Morris
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 569-579; DOI: https://doi.org/10.1124/jpet.116.233684

  3. Timár, Júlia

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  4. Tóth, Viktória E.

    1. Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium–Induced Acute Intestinal Inflammation in Mice
      Zoltán S. Zádori, Viktória E. Tóth, Ágnes Fehér, Mahmoud Al-Khrasani, Zita Puskár, Márk Kozsurek, Júlia Timár, Tamás Tábi, Zsuzsanna Helyes, Lutz Hein, Peter Holzer and Klára Gyires
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 483-491; DOI: https://doi.org/10.1124/jpet.116.235101

  5. Tsuruoka, Hiroyuki

    1. CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats
      Kiyoshi Arai, Yuka Morikawa, Naoko Ubukata, Hiroyuki Tsuruoka and Tsuyoshi Homma
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 548-557; DOI: https://doi.org/10.1124/jpet.116.234765

  6. Tunblad, Karin

    1. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain
      Ellen Hewitt, Thomas Pitcher, Biljana Rizoska, Karin Tunblad, Ian Henderson, Britt-Louise Sahlberg, Urszula Grabowska, Björn Classon, Charlotte Edenius, Marzia Malcangio and Erik Lindström
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 387-396; DOI: https://doi.org/10.1124/jpet.116.232926

U

  1. Ubukata, Naoko

    1. CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats
      Kiyoshi Arai, Yuka Morikawa, Naoko Ubukata, Hiroyuki Tsuruoka and Tsuyoshi Homma
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 548-557; DOI: https://doi.org/10.1124/jpet.116.234765

V

  1. Vanhoutte, Paul M.

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

  2. Varnäs, Katarina

    1. Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676
      Katarina Varnäs, Anders Juréus, Peter Johnström, Charlotte Ahlgren, Pär Schött, Magnus Schou, Susanne Gruber, Eva Jerning, Jonas Malmborg, Christer Halldin, Lovisa Afzelius and Lars Farde
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 464-471; DOI: https://doi.org/10.1124/jpet.116.234146

  3. Vattikundala, Pradeep

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Vikramadithyan, Reeba K.

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  5. Virtucio, Charlotte

    1. Treatment of Skin Inflammation with Benzoxaborole Phosphodiesterase Inhibitors: Selectivity, Cellular Activity, and Effect on Cytokines Associated with Skin Inflammation and Skin Architecture Changes
      Chen Dong, Charlotte Virtucio, Olga Zemska, Grober Baltazar, Yasheen Zhou, Diogo Baia, Shannon Jones-Iatauro, Holly Sexton, Shamra Martin, Joshua Dee, Yvonne Mak, Maliwan Meewan, Fernando Rock, Tsutomu Akama and Kurt Jarnagin
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 413-422; DOI: https://doi.org/10.1124/jpet.116.232819

  6. Vrakas, Christine

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

W

  1. Wang, Tao

    1. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation
      Mitsuru Seki, Ryan LaCanna, Jeffery C. Powers, Christine Vrakas, Fang Liu, Remus Berretta, Geena Chacko, John Holten, Pooja Jadiya, Tao Wang, Jeffery S. Arkles, Joshua M. Copper, Steven R. Houser, Jianhe Huang, Vickas V. Patel and Fabio A. Recchia
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 441-449; DOI: https://doi.org/10.1124/jpet.116.234591

  2. Wang, Xinkang

    1. Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
      Xueping Zhou, Weizhen Wu, Lin Chu, David E. Gutstein, Dietmar Seiffert and Xinkang Wang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 405-412; DOI: https://doi.org/10.1124/jpet.116.234575

  3. Westphal, Ryan

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  4. Whiteman, Matthew

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  5. Wilson, Alan

    1. Open Access
      Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain
      Walter Kostich, Brian D. Hamman, Yu-Wen Li, Sreenivasulu Naidu, Kumaran Dandapani, Jianlin Feng, Amy Easton, Clotilde Bourin, Kevin Baker, Jason Allen, Katerina Savelieva, Justin V. Louis, Manoj Dokania, Saravanan Elavazhagan, Pradeep Vattikundala, Vivek Sharma, Manish Lal Das, Ganesh Shankar, Anoop Kumar, Vinay K. Holenarsipur, Michael Gulianello, Ted Molski, Jeffrey M. Brown, Martin Lewis, Yanling Huang, Yifeng Lu, Rick Pieschl, Kevin O’Malley, Jonathan Lippy, Amr Nouraldeen, Thomas H. Lanthorn, Guilan Ye, Alan Wilson, Anand Balakrishnan, Rex Denton, James E. Grace, Kimberley A. Lentz, Kenneth S. Santone, Yingzhi Bi, Alan Main, Jon Swaffield, Ken Carson, Sandhya Mandlekar, Reeba K. Vikramadithyan, Susheel J. Nara, Carolyn Dzierba, Joanne Bronson, John E. Macor, Robert Zaczek, Ryan Westphal, Laszlo Kiss, Linda Bristow, Charles M. Conway, Brian Zambrowicz and Charles F. Albright
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 371-386; DOI: https://doi.org/10.1124/jpet.116.235333

  6. Witkin, Jeffrey M.

    1. A Comment on “Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8”
      Jeffrey M. Witkin and Kevin M. Gardinier
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 502-503; DOI: https://doi.org/10.1124/jpet.116.234419

  7. Wood, Mark E.

    1. Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms
      Athanasia Chatzianastasiou, Sofia-Iris Bibli, Ioanna Andreadou, Panagiotis Efentakis, Nina Kaludercic, Mark E. Wood, Matthew Whiteman, Fabio Di Lisa, Andreas Daiber, Vangelis G. Manolopoulos, Csaba Szabó and Andreas Papapetropoulos
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 431-440; DOI: https://doi.org/10.1124/jpet.116.235119

  8. Wu, Weizhen

    1. Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
      Xueping Zhou, Weizhen Wu, Lin Chu, David E. Gutstein, Dietmar Seiffert and Xinkang Wang
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 405-412; DOI: https://doi.org/10.1124/jpet.116.234575

X

  1. Xu, Aimin

    1. Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
      Charlotte M. Detremmerie, Zhengju Chen, Zhuoming Li, Khalid M. Alkharfy, Susan W.S. Leung, Aimin Xu, Yuansheng Gao and Paul M. Vanhoutte
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 558-568; DOI: https://doi.org/10.1124/jpet.116.234153

Y

  1. Yanagihara, Katsunori

    1. Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model
      Tatsuhiko Harada, Yuji Ishimatsu, Atsuko Hara, Towako Morita, Shota Nakashima, Tomoyuki Kakugawa, Noriho Sakamoto, Kosuke Kosai, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae and Shigeru Kohno
      Journal of Pharmacology and Experimental Therapeutics September 2016, 358 (3) 457-463; DOI: https://doi.org/10.1124/jpet.116.233932