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Index by author

July 01, 2016; Volume 358,Issue 1

A

  1. Abais, Justine M.

    1. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes
      Guangbi Li, Min Xia, Justine M. Abais, Krishna Boini, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 61-70; DOI: https://doi.org/10.1124/jpet.116.233239

  2. Abdelazeem, Ahmed H.

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  3. AbuTarif, Malaz

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  4. Ahlijanian, Michael K.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  5. Akinsanya, Billy

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256

  6. Albright, Charlie F.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  7. Alund, Alexander W.

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

B

  1. Badger, Thomas M.

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

  2. Baek, Nam-In

    1. Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
      Ji-Sun Shin, Hye-Eun Choi, SeungHwan Seo, Jung-Hye Choi, Nam-In Baek and Kyung-Tae Lee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 3-13; DOI: https://doi.org/10.1124/jpet.115.231043

  3. Berisha, Flora

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  4. Berman, Robert M.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256

  5. Boini, Krishna

    1. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes
      Guangbi Li, Min Xia, Justine M. Abais, Krishna Boini, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 61-70; DOI: https://doi.org/10.1124/jpet.116.233239

  6. Boy, Kenneth M.

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  7. Breit, Andreas

    1. Endogenous 5-HT2C Receptors Phosphorylate the cAMP Response Element Binding Protein via Protein Kinase C-Promoted Activation of Extracellular-Regulated Kinases-1/2 in Hypothalamic mHypoA-2/10 Cells
      Lisa Lauffer, Evi Glas, Thomas Gudermann and Andreas Breit
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 39-49; DOI: https://doi.org/10.1124/jpet.116.232397

C

  1. Carter, G.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  2. Chen, Jin-Ran

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

  3. Choi, Hye-Eun

    1. Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
      Ji-Sun Shin, Hye-Eun Choi, SeungHwan Seo, Jung-Hye Choi, Nam-In Baek and Kyung-Tae Lee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 3-13; DOI: https://doi.org/10.1124/jpet.115.231043

  4. Choi, Jung-Hye

    1. Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
      Ji-Sun Shin, Hye-Eun Choi, SeungHwan Seo, Jung-Hye Choi, Nam-In Baek and Kyung-Tae Lee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 3-13; DOI: https://doi.org/10.1124/jpet.115.231043

  5. Clarke, Wendy

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  6. Cook, Lynda

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

D

  1. Dai, Guoli

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  2. Denton, R. Rex

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  3. Dessy, Chantal

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  4. Drexler, Dieter M.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  5. Duarte, Juan

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

F

  1. Fang, Yan

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  2. Furlong, Michael

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  3. Furlong, Michael T.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256

G

  1. Gao, Jie

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  2. Gao, Na

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  3. Gasior, Maciej

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  4. Glas, Evi

    1. Endogenous 5-HT2C Receptors Phosphorylate the cAMP Response Element Binding Protein via Protein Kinase C-Promoted Activation of Extracellular-Regulated Kinases-1/2 in Hypothalamic mHypoA-2/10 Cells
      Lisa Lauffer, Evi Glas, Thomas Gudermann and Andreas Breit
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 39-49; DOI: https://doi.org/10.1124/jpet.116.232397

  5. Gómez-Gúzman, Manuel

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  6. Grace, James

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  7. Gudermann, Thomas

    1. Endogenous 5-HT2C Receptors Phosphorylate the cAMP Response Element Binding Protein via Protein Kinase C-Promoted Activation of Extracellular-Regulated Kinases-1/2 in Hypothalamic mHypoA-2/10 Cells
      Lisa Lauffer, Evi Glas, Thomas Gudermann and Andreas Breit
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 39-49; DOI: https://doi.org/10.1124/jpet.116.232397

  8. Guss, Valerie

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

H

  1. Hara, Taiki

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  2. Hiranita, Takato

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  3. Hong, Quan

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  4. Hoque, Nina

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

J

  1. Jackson, Michael F.

    1. Open Access
      Ethanol Tolerance Affects Endogenous Adenosine Signaling in Mouse Hippocampus
      Dali Zhang, Wei Xiong, Michael F. Jackson and Fiona E. Parkinson
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 31-38; DOI: https://doi.org/10.1124/jpet.116.232231

  2. Jiménez, Rosario

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  3. Johnson, B.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

K

  1. Kanai, Yoshikatsu

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  2. Katz, Jonathan L.

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  3. Kopajtic, Theresa A.

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  4. Kuriyama, Chiaki

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

L

  1. Lauffer, Lisa

    1. Endogenous 5-HT2C Receptors Phosphorylate the cAMP Response Element Binding Protein via Protein Kinase C-Promoted Activation of Extracellular-Regulated Kinases-1/2 in Hypothalamic mHypoA-2/10 Cells
      Lisa Lauffer, Evi Glas, Thomas Gudermann and Andreas Breit
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 39-49; DOI: https://doi.org/10.1124/jpet.116.232397

  2. Lee, Joonyong

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  3. Lee, Kyung-Tae

    1. Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
      Ji-Sun Shin, Hye-Eun Choi, SeungHwan Seo, Jung-Hye Choi, Nam-In Baek and Kyung-Tae Lee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 3-13; DOI: https://doi.org/10.1124/jpet.115.231043

  4. Lentz, Kimberley A.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256

  5. Lentz, Kimberly A.

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  6. León-Gómez, Elvira

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  7. Li, Guangbi

    1. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes
      Guangbi Li, Min Xia, Justine M. Abais, Krishna Boini, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 61-70; DOI: https://doi.org/10.1124/jpet.116.233239

  8. Li, Pin-Lan

    1. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes
      Guangbi Li, Min Xia, Justine M. Abais, Krishna Boini, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 61-70; DOI: https://doi.org/10.1124/jpet.116.233239

  9. Li, X.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  10. Lin, Jingmei

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  11. Ling, Yonghua

    1. Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice
      John Oberdick, Yonghua Ling, Mitch A. Phelps, Max S. Yudovich, Karl Schilling and Wolfgang Sadee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 22-30; DOI: https://doi.org/10.1124/jpet.115.231902

M

  1. Macor, John E.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  2. McCurdy, Christopher R.

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  3. Mercer, Kelly E.

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

  4. Meredith, Jere E.

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  5. Mesangeau, Christophe

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  6. Mitchell, S. N.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  7. Monn, J. A.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  8. Morrison, John

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

N

  1. Nagamori, Shushi

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  2. Nambiar, Shashank Manohar

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  3. Narayanan, Sanju

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

O

  1. Oberdick, John

    1. Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice
      John Oberdick, Yonghua Ling, Mitch A. Phelps, Max S. Yudovich, Karl Schilling and Wolfgang Sadee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 22-30; DOI: https://doi.org/10.1124/jpet.115.231902

  2. Ohgaki, Ryuichi

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  3. Okuda, Suguru

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  4. Olson, Richard E.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  5. Overshiner, C.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

P

  1. Padmanabha, Ramesh

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  2. Parkinson, Fiona E.

    1. Open Access
      Ethanol Tolerance Affects Endogenous Adenosine Signaling in Mouse Hippocampus
      Dali Zhang, Wei Xiong, Michael F. Jackson and Fiona E. Parkinson
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 31-38; DOI: https://doi.org/10.1124/jpet.116.232231

  3. Pérez-Vizcaíno, Francisco

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  4. Phelps, Mitch A.

    1. Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice
      John Oberdick, Yonghua Ling, Mitch A. Phelps, Max S. Yudovich, Karl Schilling and Wolfgang Sadee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 22-30; DOI: https://doi.org/10.1124/jpet.115.231902

  5. Pulliam, Casey F.

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

Q

  1. Qian, Xiao-Hong

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  2. Qiao, Hai-Ling

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

R

  1. Rasmussen, K.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  2. Rath, Geraldine

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  3. Raybon, Joseph

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  4. Rice, Kenner C.

    1. Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists
      Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem and Christopher R. McCurdy
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 109-124; DOI: https://doi.org/10.1124/jpet.116.232728

  5. Ritter, Joseph K.

    1. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes
      Guangbi Li, Min Xia, Justine M. Abais, Krishna Boini, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 61-70; DOI: https://doi.org/10.1124/jpet.116.233239

  6. Robertson, Alan S.

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  7. Rodríguez-Gómez, Isabel

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  8. Romero, Miguel

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  9. Ronis, Martin J. J.

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

  10. Rorick-Kehn, L. M.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  11. Rui, Wenjuan

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

S

  1. Sadee, Wolfgang

    1. Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice
      John Oberdick, Yonghua Ling, Mitch A. Phelps, Max S. Yudovich, Karl Schilling and Wolfgang Sadee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 22-30; DOI: https://doi.org/10.1124/jpet.115.231902

  2. Sánchez, Manuel

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  3. Schilling, Karl

    1. Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice
      John Oberdick, Yonghua Ling, Mitch A. Phelps, Max S. Yudovich, Karl Schilling and Wolfgang Sadee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 22-30; DOI: https://doi.org/10.1124/jpet.115.231902

  4. Schoepp, D. D.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

  5. Seo, SeungHwan

    1. Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
      Ji-Sun Shin, Hye-Eun Choi, SeungHwan Seo, Jung-Hye Choi, Nam-In Baek and Kyung-Tae Lee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 3-13; DOI: https://doi.org/10.1124/jpet.115.231043

  6. Shin, Ji-Sun

    1. Berberine Decreased Inducible Nitric Oxide Synthase mRNA Stability through Negative Regulation of Human Antigen R in Lipopolysaccharide-Induced Macrophages
      Ji-Sun Shin, Hye-Eun Choi, SeungHwan Seo, Jung-Hye Choi, Nam-In Baek and Kyung-Tae Lee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 3-13; DOI: https://doi.org/10.1124/jpet.115.231043

  7. Shiotani, Masaharu

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  8. Snow, Kimberly

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  9. Soares, Holly D.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  10. Spector, Reynold

    1. New Insight into the Dietary Cause of Atherosclerosis: Implications for Pharmacology
      Reynold Spector
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 103-108; DOI: https://doi.org/10.1124/jpet.116.233296

  11. Suva, Larry J.

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

  12. Sweeney, Francis

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

T

  1. Tamargo, Juan

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  2. Thompson, Lorin A.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  3. Tian, Xin

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  4. Toral, Marta

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  5. Toyn, Jeremy H.

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

U

  1. Ueta, Kiichiro

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

V

  1. Van Remmen, Holly

    1. Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice
      Alexander W. Alund, Kelly E. Mercer, Larry J. Suva, Casey F. Pulliam, Jin-Ran Chen, Thomas M. Badger, Holly Van Remmen and Martin J. J. Ronis
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 50-60; DOI: https://doi.org/10.1124/jpet.116.233213

W

  1. Wang, Huan-Huan

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  2. Wang, Jun-Sheng

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256
    2. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  3. Wei, Cong

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  4. Wei, Jun-Ying

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  5. Wei, Ling

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  6. Wen, Qiang

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  7. Witkin, J. M.

    1. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits
      J. M. Witkin, J. A. Monn, D. D. Schoepp, X. Li, C. Overshiner, S. N. Mitchell, G. Carter, B. Johnson, K. Rasmussen and L. M. Rorick-Kehn
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 71-82; DOI: https://doi.org/10.1124/jpet.116.233627

X

  1. Xia, Min

    1. Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes
      Guangbi Li, Min Xia, Justine M. Abais, Krishna Boini, Pin-Lan Li and Joseph K. Ritter
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 61-70; DOI: https://doi.org/10.1124/jpet.116.233239

  2. Xiong, Wei

    1. Open Access
      Ethanol Tolerance Affects Endogenous Adenosine Signaling in Mouse Hippocampus
      Dali Zhang, Wei Xiong, Michael F. Jackson and Fiona E. Parkinson
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 31-38; DOI: https://doi.org/10.1124/jpet.116.232231

Y

  1. Yamada, Kazunori

    1. Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 Inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition Kinetics, Sidedness of Action, and Transporter-Associated Incorporation Accounting for its Pharmacodynamic and Pharmacokinetic Features
      Ryuichi Ohgaki, Ling Wei, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu Shiotani, Shushi Nagamori and Yoshikatsu Kanai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 94-102; DOI: https://doi.org/10.1124/jpet.116.232025

  2. Yang, Yan

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  3. Yudovich, Max S.

    1. Preferential Delivery of an Opioid Antagonist to the Fetal Brain in Pregnant Mice
      John Oberdick, Yonghua Ling, Mitch A. Phelps, Max S. Yudovich, Karl Schilling and Wolfgang Sadee
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 22-30; DOI: https://doi.org/10.1124/jpet.115.231902

Z

  1. Zarzuelo, María José

    1. Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-<em>β</em> Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5
      Miguel Romero, Rosario Jiménez, Marta Toral, Elvira León-Gómez, Manuel Gómez-Gúzman, Manuel Sánchez, María José Zarzuelo, Isabel Rodríguez-Gómez, Geraldine Rath, Juan Tamargo, Francisco Pérez-Vizcaíno, Chantal Dessy and Juan Duarte
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 151-163; DOI: https://doi.org/10.1124/jpet.116.233106

  2. Zhang, Dali

    1. Open Access
      Ethanol Tolerance Affects Endogenous Adenosine Signaling in Mouse Hippocampus
      Dali Zhang, Wei Xiong, Michael F. Jackson and Fiona E. Parkinson
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 31-38; DOI: https://doi.org/10.1124/jpet.116.232231

  3. Zhang, Hai-Feng

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  4. Zhang, Linjie

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  5. Zhang, Yang-Jun

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  6. Zhao, Yan

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  7. Zheng, Naiyu

    1. Open Access
      The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
      Holly D. Soares, Maciej Gasior, Jeremy H. Toyn, Jun-Sheng Wang, Quan Hong, Flora Berisha, Michael T. Furlong, Joseph Raybon, Kimberley A. Lentz, Francis Sweeney, Naiyu Zheng, Billy Akinsanya, Robert M. Berman, Lorin A. Thompson, Richard E. Olson, John Morrison, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Michael K. Ahlijanian and Malaz AbuTarif
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 138-150; DOI: https://doi.org/10.1124/jpet.116.232256

  8. Zhou, Jun

    1. Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes
      Hai-Feng Zhang, Huan-Huan Wang, Na Gao, Jun-Ying Wei, Xin Tian, Yan Zhao, Yan Fang, Jun Zhou, Qiang Wen, Jie Gao, Yang-Jun Zhang, Xiao-Hong Qian and Hai-Ling Qiao
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 83-93; DOI: https://doi.org/10.1124/jpet.116.233635

  9. Zhuo, Xiaoliang

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249

  10. Zou, Yuhong

    1. Nuclear Factor Erythroid 2–Related Factor 2 Deficiency Results in Amplification of the Liver Fat-Lowering Effect of Estrogen
      Wenjuan Rui, Yuhong Zou, Joonyong Lee, Shashank Manohar Nambiar, Jingmei Lin, Linjie Zhang, Yan Yang and Guoli Dai
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 14-21; DOI: https://doi.org/10.1124/jpet.115.231316

  11. Zuev, Dmitry

    1. Open Access
      Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
      Jeremy H. Toyn, Kenneth M. Boy, Joseph Raybon, Jere E. Meredith, Alan S. Robertson, Valerie Guss, Nina Hoque, Francis Sweeney, Xiaoliang Zhuo, Wendy Clarke, Kimberly Snow, R. Rex Denton, Dmitry Zuev, Lorin A. Thompson, John Morrison, James Grace, Flora Berisha, Michael Furlong, Jun-Sheng Wang, Kimberly A. Lentz, Ramesh Padmanabha, Lynda Cook, Cong Wei, Dieter M. Drexler, John E. Macor, Charlie F. Albright, Maciej Gasior, Richard E. Olson, Quan Hong, Holly D. Soares, Malaz AbuTarif and Michael K. Ahlijanian
      Journal of Pharmacology and Experimental Therapeutics July 2016, 358 (1) 125-137; DOI: https://doi.org/10.1124/jpet.116.232249
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